David Abraham, PhD

Contact Dr. Abraham

233 South 10th Street

Philadelphia, PA 19107

(215) 503-8917
(215) 923-9248 fax

Research and Clinical Interests
Role of eosinophils, neutrophils and macrophages in innate

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Publications

Most recent Peer-reviewed Publications

1. Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model
2. B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fcα/μ receptor and in the absence of host cell contact
3. Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice
4. Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice
5. Soluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitment
6. Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis
7. Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in northern Argentina
8. IL-4-/- mice with lethal Mesocestoides corti infections - Reduced Th2 cytokines and alternatively activated macrophages
9. Eosinophils utilize multiple chemokine receptors for chemotaxis to the parasitic nematode strongyloides stercoralis
10. B Cell Multitasking Is Required to Control Nematode Infection
11. Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice
12. The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model
13. A randomized clinical trial comparing oral azithromycin and meglumine antimoniate for the treatment of American cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis
14. Signaling through Gαi2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice
15. Toll-like receptor 4 (TLR4) is required for protective immunity to larval Strongyloides stercoralis in mice
16. Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval Strongyloides stercoralis in mice
17. Eosinophils can function as antigen-presenting cells to induce primary and secondary immune responses to Strongyloides stercoralis
18. Complement component C3 is required for protective innate and adaptive immunity to larval strongyloides stercoralis in mice
19. Protective immunity to the larval stages of Onchocerca volvulus is dependent on toll-like receptor 4
20. DNA immunization with Na+-K+ATPaSe (Sseat-6) induces protective immunity to larval Strongyloides stercoralis in mice

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