Kerry S. Campbell, PhD

Contact Dr. Campbell

333 Cottman Avenue
Fox Chase Cancer Center
Philadelphia, PA 19111

(215) 728-7761
(215) 728-2412 fax

Research and Clinical Interests
Signal Transduction in Natural Killer Cells

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Publications

Most recent Peer-reviewed Publications

1. Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes
2. Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity
3. B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K
4. Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44
5. Structure/function of human killer cell immunoglobulin-like receptors: Lessons from polymorphisms, evolution, crystal structures and mutations
6. Ubiquitylation of an internalized killer cell Ig-like receptor by Triad3A disrupts sustained NF-kB signaling
7. Natural killer cells and cancer: Regulation by the Killer cell Ig-like Receptors (KIR)
8. Introduction of shRNAs into human NK-like cell lines with retrovirus.
9. Expression of cDNAs in human Natural Killer cell lines by retroviral transduction.
10. Measuring intracellular calcium signaling in murine NK cells by flow cytometry.
11. Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations
12. Immunotherapy of cancer
13. Natural killer cells and cancer: Regulation by the killer cell ig-like receptors (KIR)
14. SHP-2 expression negatively regulates NK cell function
15. NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells
16. Enhanced NK-cell development and function in BCAP-deficient mice
17. Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy
18. KIR2DL4 differentially signals downstream functions in human NK cells through distinct structural modules
19. Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells
20. Prostaglandin D2 suppresses human NK cell function via signaling through D prostanoid receptor

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