D. Craig Hooper, PhD

Contact Dr. Hooper

1020 Locust Street
Room 452
Philadelphia, PA 19107

(215) 503-1774
(215) 923-7745 fax

Research and Clinical Interests
The principle research area of the Hooper laboratory is CNS immunity and, particularly, the balance between protective and destructive neuroinflammatory processes.

Show Details

Publications

Most recent Peer-reviewed Publications

1. Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure
2. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei
3. Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis
4. Rabies Virus Clearance from the Central Nervous System
5. The Role of Toll-Like Receptors in the Induction of Immune Responses During Rabies Virus Infection
6. Therapeutic immune clearance of rabies virus from the CNS
7. Plant vaccines: An immunological perspective
8. Modulation of serum uric acid levels by inosine in patients with multiple sclerosis does not affect blood pressure
9. IL-4-/- mice with lethal Mesocestoides corti infections - Reduced Th2 cytokines and alternatively activated macrophages
10. Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy
11. The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system
12. Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus
13. The treatment of multiple sclerosis with inosine.
14. Immune evasion by rabies viruses through the maintenance of blood-brain barrier integrity
15. Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity
16. Serum and cerebrospinal fluid uric acid levels in multiple sclerosis patients
17. Early blood-brain barrier permeability in cerebella of PLSJL mice immunized with myelin basic protein
18. Lethal silver-haired bat rabies virus infection can be prevented by opening the blood-brain barrier
19. A peroxynitrite-dependent pathway is responsible for blood-brain barrier permeability changes during a central nervous system inflammatory response: TNF-α is neither necessary nor sufficient
20. Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models

View All Publications