Dr. Quong Andrew Alan Quong, PhD

Contact Dr. Quong

233 South 10th Street
Suite 348
Philadelphia, PA 19107

(215) 503-9273
(215) fax

Research and Clinical Interests
Proteomics and Computational biology aimed at understanding the basic mechanisms of tumorigenesis and metastasis and for the development of new molecular interventions. Development of new technologies for clinical diagnostics. Discovery of Molecular markers for early detection of breast and thyroid cancer and for prediction of response to therapy

Publications

Most recent Peer-reviewed Publications

  1. Growth of v-src-transformed cells in serum-free medium through the induction of growth factors
  2. Dachshund binds p53 to block the growth of lung adenocarcinoma cells
  3. Proteomic profiling of infiltrating ductal carcinoma reveals increased cellular interactions with tissue microenvironment
  4. Low abundance protein enrichment for discovery of candidate plasma protein biomarkers for early detection of breast cancer
  5. An integrated framework to model cellular phenotype as a component of biochemical networks
  6. The canonical NF-κB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion
  7. microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
  8. Attenuation of Forkhead signaling by the retinal determination factor DACH1
  9. Anti-inflammatory compounds parthenolide and bay 11-7082 are direct inhibitors of the inflammasome
  10. Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells
  11. Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome
  12. Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts
  13. Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation
  14. Hormonal control of androgen receptor function through SIRT1
  15. p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/β-catenin signaling
  16. Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function
  17. Cyclin D1 determines mitochondrial function in vivo
  18. Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling
  19. Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate
  20. A three-dimensional model of intercellular calcium signaling in epithelial cells

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