Isidore Rigoutsos, PhD

Contact Dr. Rigoutsos

1020 Locust Street
Jefferson Alumni Hall
Philadelphia, PA 19107

(215) 503-6152
(215) 955-5058 fax

Research and Clinical Interests
Pattern discovery; motif discovery; regulatory motifs; microRNAs; miRNAs; piRNAs; microRNA and piRNA targeting; non-coding RNAs; RNAi; RNA interference; retrotransposons; cell process regulation; genomics; computational genetics; computational medicine; diagnostics; therapeutics; high-throughput sequencing analysis; microbial genomics; metagenomics; high performance computing.

Publications

Most recent Peer-reviewed Publications

1. The microRNAs within the DLK1-DIO3 genomic region: Involvement in disease pathogenesis
2. The complex transcriptional landscape of the anucleate human platelet
3. ERRATUM: Molecular dynamics simulations of Ago silencing complexes reveal a large repertoire of admissible 'seed-less' targets (Scientific Reports (2012) 2 (569) DOI: 10.1038/srep00569)
4. Interactive exploration of RNA22 microRNA target predictions
5. MicroRNAs in colon cancer: A roadmap for discovery
6. Molecular dynamics simulations of Ago silencing complexes reveal a large repertoire of admissible 'seed-less' targets
7. HuR's post-transcriptional regulation of death receptor 5 in pancreatic cancer cells
8. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC
9. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
10. Evaluation of methods for de novo genome assembly from High-Throughput sequencing reads reveals dependencies that affect the quality of the results
11. The Evi1, microRNA-143, K-Ras axis in colon cancer
12. OMiR: Identification of associations between OMIM diseases and microRNAs
13. 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010: Message from the general chairs
14. Gene-expression forum: Decoy for microRNAs
15. Anchoring millions of distinct reads on the human genome within seconds
16. Dynamic changes in the human methylome during differentiation
17. Short RNAs: How Big Is This Iceberg?
18. Atypical transcription of microRNA gene fragments
19. Insights into the regulation of a common variant of HMGA2 associated with human height during embryonic development
20. Alu and B1 repeats have been selectively retained in the upstream and intronic regions of genes of specific functional classes

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