Charles P. Scott, PhD

Contact Dr. Scott

233 South 10th Street
Suite 833
Philadelphia, PA 19107

(215) 503-4569
(215) 923-2117 fax

Research and Clinical Interests
Combinatorial target and drug discovery; chemical genomics of host-pathogen interactions and cancer.

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Publications

Most recent Peer-reviewed Publications

1. EEG knows best: Predicting future performance problems for targeted training
2. Talk like an electrician: Student dialogue mimicking behavior in an intelligent tutoring system
3. Adaptive intelligent tutorial dialogue in the BEETLE II system
4. Anti-inflammatory compounds parthenolide and bay 11-7082 are direct inhibitors of the inflammasome
5. Taking the chemical out of chemical genetics
6. Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Eμ-TCL1 transgenic mice
7. Use of inteins for the in vivo production of stable cyclic peptide libraries in E. coli.
8. A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit
9. Structural requirements for the biosynthesis of backbone cyclic peptide libraries
10. A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase
11. Production of cyclic peptides and proteins in vivo
12. High level expression of the large subunit of mouse ribonucleotide reductase in a baculovirus system