Theodore F. Taraschi, PhD

Contact Dr. Taraschi

1020 Locust Street
Jefferson Alumni Hall, Suite 209
Philadelphia, PA 19107

(215) 503-5020
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Research and Clinical Interests
The invasion of erythrocytes by Plasmodium falciparum parasites produces aninfection

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Publications

Most recent Peer-reviewed Publications

1. Malaria drug resistance is associated with defective DNA mismatch repair
2. The longin domain regulates the steady-state dynamics of sec22 in plasmodium falciparum
3. A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum
4. Expression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1)
5. Expression and biochemical characterization of Plasmodium falciparum DNA ligase I
6. Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains
7. Effects of D-myo-inositol 1-phosphate on the transfer function of phosphatidylinositol transfer protein α
8. L-α-Glycerylphosphorylcholine inhibits the transfer function of phosphatidylinositol transfer protein α
9. Generation of an erythrocyte vesicle transport system by Plasmodium falciparum malaria parasites
10. Evidence of an intraerythrocytic secretory pathway in erythrocytes infected with Plasmodium falciparum
11. Vesicle-mediated trafficking of parasite proteins to the host cell cytosol and erythrocyte surface membrane in Plasmodium falciparum infected erythrocytes
12. Phospholipid-bound β2-glycoprotein I induces the production of anti-phospholipid antibodies
13. Gelonin is an unusual DNA glycosylase that removes adenine from single-stranded DNA, normal base pairs mismatches
14. Activity of phosphatidylinositol transfer protein is sensitive to ethanol and membrane curvature
15. Letter to the editor [2]
16. Evidence for vesicle-mediated trafficking of parasite proteins to the host cell cytosol and erythrocyte surface membrane in Plasmodium falciparum infected ertythrocytes
17. DNA base excision repair in human malaria parasites is predominantly by a long-patch pathway
18. Direct binding of lupus anticoagulant antibodies to nonbilayer phosphatidylethanolamine
19. Characterization of class II apurinic/apyrimidinic endonuclease activities in the human malaria parasite, Plasmodium falciparum
20. Macromolecular transport in malaria-infected erythrocytes

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