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Sudarshan Phani
| Contact |
sxp949@jefferson.edu |
| Lab/PI |
Lorraine Iacovitti, PhD |
| Undergrad |
B.S. Neuroscience, New York University – 2004 |
Research Interests:
My current research is focused on trying to find specific genes responsible for Parkinson’s disease related cell death in the substantia nigra. Using the MPTP mouse model of Parkinson’s disease, I am comparing the relatively vulnerable substantia nigra to the neighboring ventral tegmental area, which is relatively protected in Parkinson’s disease.
I am also working on a focal ischemic stroke model in rats. The research is focused on using different types and stages of stem cells that can be transplanted into the affected area. These cells have the potential to differentiate into mature neurons, and help recover function that was lost due to ischemic stroke.
Selected Publications:
Gilbert ME, Sui L, Walker MJ, Anderson W, Thomas S, Smoller SN, Schon JP, Phani S, Goodman JH. Thyroid Hormone Insufficiency During Brain Development Reduces Parvalbumin Immunoreactivity and Inhibitory Function in the Hippocampus. Endocrinology. 2006 Sep 28. [Epub ahead of print]
Scharfman H, Goodman J, Macleod A, Phani S, Antonelli C, Croll S. Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp Neurol. 2005 Apr;192(2):348-56.
Selected Abstracts:
Gilbert M.E., Schon J.P., Phani S., Goodman J.H. Developmental Hypothyroidism Induces a Cortical Malformation Populated by Neurons Born Late in Gestation. Program Number 480.23. Society for Neuroscience, 2005.
Goodman J.H., Schon J.P., Phani S., Zucker J.R. Postictal Low Frequency Sine Wave Stimulation Decreases the Incidence of Kindled Seizures. Assignment Number 2.039. American Epilepsy Society and American Clinical Neurophysiology Society Joint Annual Meeting, 2005.
Goodman J.H., Schon J.P., Phani S., Pathrose M., Gilbert M.E. Developmental hypothyroidism alters the expression of calretinin in the cortex and hippocampus of the rat. Program Number 832.5/HH10. Society for Neuroscience, 2006.
Memberships, Honors, Awards:
Irving H. Jurrow Scholar – New York University 2000-2004
Society for Neuroscience
AAAS Member
Personal:
Being a graduate student doesn’t allow for too much on the side, but I manage to get out every now and again. I love live music, playing poker and drinking wine. During the winter months you’ll probably find me skiing. Exhilarating and relaxing all at the same time, it’s my true getaway from the confines of everyday life.
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