Course Profile

AdvTop Protein Func & Dysfunct  ( 3.00 credits )

Subject:BI
Course Number:612
CRN Number:71001
Term:Fall 2013
Starting date:  09/03/2013 
Ending date:  11/30/2013 
Meeting Day:  Mon, Wed, Fri 
Meeting Time:  10:00 am-11:00 am 
Regularly assigned classroom:  BLSB 202 
Prerequisites:  GC 550 
Instructor:  Wickstrom 

Course Description: 

The course is intended to familiarize students with the native structures and dynamics of proteins and nucleic acids. Students will present literature articles followed by class discussions. Presenters are to organize the material according to the course goals, condense the material in order to allow discussion and critique it in terms of feasibility of approach, data and further research application. Topics include the thermodynamic stability of proteins and nucleic acids, the roles of kinetics and thermodynamics in protein and nucleic acid folding, predictive schemes for protein folding and an analysis of the loss of stability in mismatched DNA and its biological and biochemical implications. 

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