AdvTop Protein Func & Dysfunct ( 3.00 credits )
|Meeting Day:||Mon, Wed, Fri|
|Meeting Time:||10:00 am-11:00 am|
|Regularly assigned classroom:||BLSB 202|
The course is intended to familiarize students with the native structures and dynamics of proteins and nucleic acids. Students will present literature articles followed by class discussions. Presenters are to organize the material according to the course goals, condense the material in order to allow discussion and critique it in terms of feasibility of approach, data and further research application. Topics include the thermodynamic stability of proteins and nucleic acids, the roles of kinetics and thermodynamics in protein and nucleic acid folding, predictive schemes for protein folding and an analysis of the loss of stability in mismatched DNA and its biological and biochemical implications.