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Jay H. Herman, M.D.

Jay H. Herman, M.D.

Dr. Jay Herman has been a member of the Cardeza Foundation for Hematologic Research at Thomas Jefferson University since 2001. He serves as the Director of Transfusion Medicine for Thomas Jefferson Hospital and the Program Director for the fellowship program in Blood Banking/Transfusion Medicine. He practices General Hematology in the Department of Medicine.

Dr. Herman graduated from Harvard Medical School and trained in Pediatrics at Grady Memorial Hospital and the University of Virginia Medical Center. He received subspecialty training at Johns Hopkins Hospital in Pediatric Hematology/Oncology, Clinical Pathology and Blood Banking, and Adult Hematology.

From 1986 until 2001, Dr. Herman held hospital and faculty appointments in Transfusion Medicine and Clinical Pathology at a number of institutions in Philadelphia: the Penn-Jersey Regional Blood Center of the American Red Cross, Temple University Hospital and School of Medicine, and St. Christopher's Hospital for Children. Dr. Herman returned to patient care in 1999 as a clinical member of the Bone Marrow Transplant Program at Temple, serving as Medical Director of Stem Cell Processing and Collection.

Dr. Herman's research interests have been focused in the fields of platelet transfusion practice, pediatric transfusion, platelet and neutrophil immune disorders, blood stem cell collection and new apheresis technology. His clinical interests have focused on laboratory management, immunohematologic disorders and non-malignant hematologic diseases of children and adults, especially platelet disorders.

Selected Publications:

1. Kickler TS, Ness PM, Herman JH, Bell WR. Studies on the pathophysiology of posttransfusion purpura. Blood 1986; 68:347-350.
   
   
2. Herman JH, Jumbelic MI, Ancona RJ, Kickler TS. In utero cerebral hemorrhage in alloimmune thrombocytopenia. American Journal of Pediatric Hematology/Oncology 1986; 8:312-317.
   
   
3. Herman JH, Whiteheart W, Shirey RS, Johnson RJ, Kickler TS, Ness PM. Red cell Th activation: biochemical studies. British Journal of Hematology 1987; 65:205-209.
   
   
4. Herman JH, Shirey RS, Smith B, Kickler TS, Ness PM. Th activation in congenital hypoplastic anemia. Transfusion 1987; 27:253-256.
   
   
5. Kickler TS, Herman JH, Furihata K, Kunicki TJ, Aster RH. Identification of Bakb: a new platelet specific antigen associated with post transfusion purpura. Blood 1988; 71:894-898.
   
   
6. Stroncek DF, Skubitz KM, Plachta LB, Shankar RA, Clay ME, Herman JH, Fleit HB, McCullough J. Alloimmune neonatal neutropenia due to an antibody to the neutrophil Fc-? receptor III with maternal deficiency of CD16 antigen. Blood 1991; 77:1572-1580.
   
   
7. Klumpp TR, Herman JH, Mangan KF, Macdonald JS. Graft failure following neutrophil-specific alloantigen mismatched allogeneic bone marrow transplantation. Bone Marrow Transplantation 1993; 11:243-245.
   
   
8. Goodstein MH, Locke RG, Wlodarczyk DW, Goldsmith LS, Rubinstein DS, Herman JH. A comparison of two preservation solutions for erythrocyte transfusions in newborn infants. Journal of Pediatrics 1993; 123:783-788.
   
   
9. Klumpp TR, Herman JH, Mangan KF, Schnell MK, Goldberg SL, Macdonald JS. Lack of transmission of anti-neutrophil and anti-platelet antibodies by intravenous immunoglobulin in bone marrow transplant patients. Transfusion 1994; 34:677-679.
   
   
10. Beadling WV, Herman JH, Stuart MJ, Keashen-Schnell M, Miller JL. Fetal bleeding in NAIT mediated by anti-PlA1 is not associated with inhibition of fibrinogen binding to platelet GPIIb/IIIa. American Journal of Clinical Pathology 1995; 103:636-641.
    
    
11. Klumpp TR, Herman JH, Innis S, Pearlman E, Culling N, Kotz KW, Slachta C, Goldberg SL, Mangan KF. Factors associated with response to platelet transfusion following hematopoietic stem cell transplantation. Bone Marrow Transplantation 1996; 17:1035-1041.
    
    
12. Klumpp TR, Herman JH, Schnell MK, Goldberg SL, Mangan KF. Association between antibodies reactive with neutrophils, rate of neutrophil engraftment and incidence of post-engraftment neutropenia following BMT. Bone Marrow Transplantation 1996; 18:559-564.
    
    
13. Klumpp TR, Herman JH, Gaughan JP, Russo RR, Christman RA, Goldberg SL, Ackerman SJ, Bleecker GC, Mangan KF. Clinical consequences of alterations in platelet transfusion dose: a prospective, randomized, double-blind trial. Transfusion 1999; 39:674-681.
    
    
14. Ackerman SJ, Klumpp TR, Herman JH, Guzman GI, Goldberg SL, Gaughan JP, Magdalinski AJ, Bleecker GC, Mangan KF. Economic consequences of alterations in platelet transfusion dose: analysis of a prospective, randomized, double-blind trial. Transfusion 2000; 40:1457-1462.
    
    
15. Klumpp TR, Herman JH, Ulicny J, Emmons RVB, Martin ME, and Mangan KF. Lack of effect of donor-recipient ABO mismatching on outcome following allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation 2006; 38: 615-620.
    
    
16. Wirk B, Klumpp TR, Ulicny J, Herman JH, Gajewski JL, Martin ME, Emmons RVB, Mangan KF.  Lack of effect of donor-recipient Rh mismatch on outcomes following allogeneic hematopoietic stem cell transplantation. Transfusion 2008; 48: 163-168.
    
    
17. Doria C, Elia E, Kang Y, Adam A, Desormeaux A, Ramirez C, Frank A, di Francesco F, Herman JH.  Acute hypotensive transfusion reaction during liver transplantation in a patient on ACE inhibitors from low aminopeptidase P activity.  Liver Transplantation 2008; 14: 684-687.
    
    
18. Ayache S and Herman JH.  Prevention of RhD sensitization after mismatched transfusion of blood components: Towards optimal use of anti-RhD immunoglobulin. Transfusion 2008; 48: 1990-1999.
    
    

Selected Chapters:

1. Herman JH, Benson K. Platelet Transfusion Therapy. In: Mintz PD, ed. Transfusion Therapy: Clinical Principles and Practice, second edition, AABB Press:Bethesda, MD, pp.335-353, 2004.
   
   
2. Herman JH, Klumpp TR. Transfusion Medicine. In: Williams ME and Kahn MJ, eds. American Society of Hematology Self-Assessment Program, second edition, Blackwell:Malden, MA, pp.343-369, 2005.
   
   
3. Herman JH. Transfusion Medicine. In: McCrae KR and Mason BA, eds. Hematology Section, Medical Knowledge Self-Assessment Program 14, American College of Physicians:Philadelphia, PA, pp.43-50, 2006.
   
   
4. Dent GA, Herman JH and Siegel JE. Laboratory Hematology. In: Kahn MJ and Gregory SA, eds. American Society of Hematology Self-Assessment Program, third edition, Blackwell:Malden, MA, pp. 444-465, 2007.
   
   
5. Bruno D and Herman JH. Anemia and Transfusion Medicine. In: Comprehensive Hospital Medicine, An Evidence Based and System Approach. Williams MV, Flanders SA, Whitcomb W, Cohen S, Michota F, Holman R, Gross R, and Merli GJ. Elsevier Publishing, Philadelphia, PA, pp. 569-576, 2007.
   
   
6. Snyderman D and Herman JH. Hematology: Immune Thrombocytopenia Purpura. In: Ebell, M, ed. Evidence at Hand. John Wiley & Sons, Inc., Hoboken, NJ. (in press).
   
   
7. Alvandi F, Ayache S, Drum E, and Herman JH. Use of Blood Components. In: Criner GJ, Barnette R, and D’Alonzo G, eds. Critical Care Study Guide, 2nd edition, Springer-Verlag: New York, NY. (in press).

Books:

1. Current Issues in Platelet Transfusion Therapy and Platelet Alloimmunity, Kickler TS and Herman JH, eds. AABB Press: Bethesda, MD, 1999.
   
   
2. Pediatric Transfusion Therapy, Herman JH and Manno CS, eds. AABB Press: Bethesda, MD, 2002.