Pavillion Building, Room 207
Philadelphia, PA 19107
(215) 955-0611
Most Recent Peer-reviewed Publications
- MicroRNA profiling in lung cancer reveals new molecular markers for diagnosis
- Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model
- Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression
- Assessment of fine needle aspiration specimen adequacy for high-risk HPV detection and genotyping in oropharyngeal squamous cell carcinoma
- Detection of merkel cell carcinoma polyomavirus in mucosal merkel cell carcinoma
University Appointment
Research Assistant Professor
Research and Clinical Interests
My research interests are concentrated on geonomic and personalized medicine. I recently established the Pathology Translational Genomics Laboratory and serve as Scientific Director of the facility. We have developed the capabilities for performing whole genome profiling for the analysis of microDNA expression, DNA methylation, and DNA copy number changes by array comparative genomic hybridization using current microarray technology. The laboratory also has developed next generation sequencing technology using Roche 454 FLEX sequencer. Applications that are in progress include RNA seq, ChIP seq, genome mutation detection, and verification of DNA methylation with bisulfite conversion. I collaborate with basic scientists and clinicians to study molecular mechanisms of human diseases with an emphasis on the changes at the genomic level.