Research & Publications > Publications  1999 - 2004

Publications 1999 - 2004

Billington, C.K., I.P. Hall, S.J. Mundell, J.-L. Parent, R.A. Panettieri Jr., J.L. Benovic, and R.B. Penn. Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. Am J Respir Cell Mol Biol 21:597-606, 1999.

Marik PE , Careau P. The Role of Anaerobes in Patients with Ventilator-associated Pneumonia and Aspiration Pneumonia: a Prospective Study. Chest 1999; 115:178-183.

Orsini, M.J., V. Krymskaya, A. Eszterhas, J.L. Benovic, R.A. Panettieri Jr., and R.B. Penn. Role of MAP kinase superfamily in human airway smooth muscle mitogenesis. Am J Physiol:(Lung Cell Mol Physiol) 277:L479-L488, 1999.

Krymskaya, V.P., R.B. Penn, M.J. Orsini, P.H. Scott, R.J. Plevin, T.R. Walker, A.J. Eszterhas, E.R. Chilvers, and R.A. Panettieri, Jr. Phosphatydilinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation. Am J Physiol:(Lung Cell Mol Physiol) 277:L65-L78, 1999.

Marik PE , Varon J, Fromm RE. Carbon Monoxide Poisoning: A Review For Clinicians. J Emerg Med 1999; 17:87-93

Penn, R.B., J.-L. Parent, A.N. Pronin, R.A. Panettieri, Jr., and J.L. Benovic. Pharmacological inhibition of protein kinases in intact cells: Antagonism of beta-adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. J Pharmaco. Exp Ther 288:428-437, 1999.

Leone FT, Grana JR, McDermott P, MacPherson S, Hanchak NA, Fish JE. Pharmaceutically based severity stratification of an asthmatic population. Respir Med 1999; 93: 788-793.

Kane GC. Scholarly activity in Internal Medicine Residency Training. The Jefferson Medicine Forum. 1999

Marik PE, Anticonvulsant Hypersensitivity Syndrome Presenting as Septic Shock and Multi-System Organ Failure. Pharmacotherapy 1999;19:346-348.

Mangione S, Nieman Z. Pulmonary Auscultatory Skills During Internal Medicine and Family Practice Training: A Comparison of Diagnostic Proficiency. Am J of Respir and Crit Care Med 1999;159:119-1124.

Mangione S and Peitzman SJ. Revisiting Physical Diagnosis During Medical residency: Is It Time for a Logbook? Academic Medicine 1999; 74( 5):467-469.

Mangione S. "The Teaching of Lung Auscultation during Internal Medicine and Family Practice Training: a nationwide survey". Academic Medicine 1999: 74 (10), S90-92.

Marik PE. Stress Ulcer Prophylaxis: A Practical Approach. J Intensive Care Med 1999; 14:1-8.

Marik PE. Total splanchnic Resuscitation (TSR), SIRS, and MODS. [Editorial]. Crit Care Med 1999; 27:257-258.

Marik PE , Krikorian J, Hogan J. The bioavailability of albuterol in mechanically ventilated patients using different delivery devices. Chest 1999; 115: 1653-1666.

Sathiraju S, Iglesias J, Marik, PE. Severe SIRS with Shock and ARDS resulting from Stills disease: Clinical response with high dose pulse methylprednisolone therapy. Chest 1999; 115:1738-1740.

Bowman K, Nordstrom CR, Steiner R, and Kane,GC. Asthma and Allergic Bronchopulmonary Aspergillosis; CT appearance. Clin Pulm Med 1999;6:207-209.

Garcia-Manero G. Schuster SJ. Patrick H. Martinez J. Pulmonary hypertension in patients with myelofibrosis secondary to myeloproliferative diseases. American Journal of Hematology. 60(2):130-5, 1999.

Shetty A, Kane, GC. Tuberculous Peritonitis. In Tuberculosis, D. Schlossberg (Ed) 1999 WB Saunders, Philadelphia, Pennsylvania.

Fish JE. Peters SP. Airway remodeling and persistent airway obstruction in asthma. Journal of Allergy & Clinical Immunology. 104(3 Part 1):509-516, 1999

Martin RJ, Pak J, Kunselman SJ, Cherniak RM, [Fish JE, et al] for the Asthma Clinical Research Network. Assessment of the AirWatchä Lung function Monitoring System. J Allergy Clin Immunol 103:535-536, 1999.

Marik PE , Abraham G, Careau P. The ex-vivo Antimicrobial activity and colonization rate of two antimicrobial bonded central venous catheters. Crit Care Med 1999; 27:1128-1131.

Marik PE , Chen K, Varon J, Sternback GL, Fromm R. Management of Increased Intracranial Pressure: A Review for Clinicians. J Emerg Med 1999; 17:711-719.

Marik PE , Iglesias J. Intestinal Mucosal Permeability: Mechanisms and Implications for Treatment.[Editorial] Crit Care Medicine 1999; 27:1650-1651.

Marik PE. Varon J. Severity Scoring and Outcome Assessment: Computerized Predictive Models and Scoring Systems. Crit Care Clinics 1999; 15(3):633-646.

Varon J, Marik PE. Critical Care and the World Wide Web. Crit Care Clinics1999; 15(3): 593-604.

Marik PE, Varon J. Steroids in acute exacerbation of asthma. How do we grade the evidence? Chest 1999; 116:273-275.

Varon J,. Sternbach GL, Marik PE , Fromm RE. Automatic External Defibrillators: Past, Present and Future. Resuscitation 1999;41: 219-223.

Leone FT. Grana JR. McDermott P. MacPherson S. Hanchak NA. Fish JE. Pharmaceutically-based severity stratification of an asthmatic population. Respiratory Medicine. 93(11):788-793, 1999

Marik PE , Iglesias J. Low-dose Dopamine Fails to Prevent Acute Renal Failure while High-Dose Dopamine Increases Mortality in Oliguric Septic Shock Patients. Am J Med. 1999; 107:387-389.

Marik PE , Haupt HT . Dopexamine and the splanchnic paradox. Crit Care Med 1999: 27:2301-2303.

Fish JE. Peters SB. Asthma severity: Histopathologic correlations. Drugs of Today. 35(8):585-594, 1999

Peters SP. Fish JE. Prior use of long-acting beta-agonists: Friend or foe in the emergency department?. American Journal of Medicine. 107(3):283-285, 1999

Fish JE, Peters SP. Gastroesophageal reflux and upper airways disease in severe asthma. In, Difficult Asthma. Holgate ST, Boushey HA, Fabbri LM (eds). London: Martin Dunitz, Ltd., 1999, pp. 77-91.

Marik PE. Splanchnic resuscitation. First International Congress of Critical Care on the Internet. November 17, 1999. http://www.uninet.edu/cimc99/seminarios/marik/tsr_archivos/v3_document.htm

Mangione S, LaCombe M. Toward Optimal Health: The Experts Respond to the Art of Diagnosis. Journal of Womens Health & Gender-Based Medicine 2000: 9(3): 215-222.

Weitz H, Mangione S. In defense of the Stethoscope and the Bedside Invited Editorial by The American Journal of Medicine. Am J Med 2000: 108 (8): 669-671.

Israel E. Drazen JM. Liggett SB. Boushey HA. Cherniack RM. Chinchilli VM. Cooper DM. Fahy JV. Fish JE. Ford JG. Kraft M. Kunselman S. Lazarus SC. Lemanske RF. Martin RJ. McLean DE. Peters SP. Silverman EK. Sorkness CA. Szefler SJ. Weiss ST. Yandava CN. The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. American Journal of Respiratory & Critical Care Medicine. 162(1):75-80, 2000

Colavita AM. Reinach AJ. Peters SP. Contributing factors to the pathobiology of asthma - The Th1/Th2 paradigm. Clinics in Chest Medicine. 21(2):263-+, 2000

Marik PE . Fever in the ICU. Chest 2000; 117:855-869

Mc Cowan C, Marik PE. Refractory Delirium Tremens Treated with Propofol: A Case Series. Crit Care Med 2000; 28:1781-1784.

Crapo RO. Casaburi R. Coates AL. Enright PL. Hankinson JL. Irvin CG. MacIntyre NR. McKay RT. Wanger JS. Anderson SD. Cockcroft DW. Fish JE., Sterk PJ. Guidelines for methacholine and exercise challenge testing - 1999. American Journal of Respiratory & Critical Care Medicine. 161(1):309-329, 2000

Colavita AM, Hastie AT, Musani AI, Pascual RM, Reinach AJ, Lustine HT, Galati S, Zangrilli JG, Fish JE, Peters SP. Kinetics of IL-10 production after segmental antigen challenge of atopic asthmatics. J Allergy Clin Immunol 106:880-886, 2000.

Zangrilli, J., Robertson, N.M., Shetty, A., Wu, J., Hastie, A.T., Fish, J.E.,Litwack, G., Peters, S.P. Effect of interleukin-5, glucocorticoid, and fas-ligation on bcl-2 homologue expression and caspase activation in circulating human eosinophils J. Clin. Exper. Immunol. 2000, 120:12-21.

Lang DM. Visintainer PF. Howland WC. Stein M. Villareal M. Survey of the extent and nature of care for adults and older adults by allergy/immunology practitioners. Annals of Allergy, Asthma, & Immunology. 85(2):106-110, 2000

Marik PE , Varon J. The Diagnosis and Management of Hypertensive Crisis. Chest 2000; 118:214-227.

Marik PE , Iglesias J. would the colloid detractors please sit down! Crit Care Med 2000; 28:2652-2654.

Barsigian C, Kane GC. Primary Coccidioidal Cavity in a Woman with travel to Arizona. Clin Pulm Med 2000;7:85.

Lang DM. Antileukotriene agents and aspirin-sensitive asthma: are we removing the second bassoonist or skating to where the puck is gonna be?. Annals of Allergy, Asthma, & Immunology. 85(1):5-8, 2000

Varon J, Marik PE. Self-assessment in Critical Care Medicine. Sepsis: review questions. Hospital Physician 2000; 36; 51-52.

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network [see comments]. New England Journal of Medicine. 342(18):1301-8, 2000 (Gottlieb)

Marik PE , Zaloga GP. Hypothermia and Cytokines in Septic Shock. Intensive Care Med; 2000; 26:716-721

Zangrilli, J.G., Peters, S.P. Chapter 38: Cytokines in allergic airways disease. In: Asthma and Rhinitis. (Eds.: W. Busse and S. Holgate). Blackwell Scientific Publications, Boston, 2000.

Ammit, A.J., R.K. Hoffman, Y. Amrani, A.L. Lazaar, D.W.P. Hay, T.J. Torphy, R.B. Penn, and R.A. Panettieri, Jr. TNFa-induced secretion of RANTES and IL-6 from human ASM cells: Modulation by cAMP. Am J Respir Cell Mol Biol 23:794-802, 2000.

Krymskaya, V.P., M.J. Orsini, A. Eszterhas, J.L. Benovic, R.A. Panettieri Jr., and R.B. Penn. Potentiation of human airway smooth muscle proliferation by Receptor Tyrosine Kinase and G protein-coupled receptor activation. Am J Respir Cell Mol Biol 23:546-554, 2000.

Marik PE , Varon J. Steroids in asthma. Postgrad Med 2000; 107; 227.

Santini, F., R.B. Penn, A.W. Gagnon, J.L. Benovic, and J.H. Keen. Selective recruitment of arrestin-3 to clathrin-coated pits upon stimulation of G protein-coupled receptors. J Cell Signal 113:2463-2470, 2000.

Marik PE , Varon J. Adjunctive corticosteroids in the management of tuberculosis. Postgrad Med 2000; 10:102-103.

Kane GC. Errors in the ICU: "Near Misses in Cardiothoracic Critical Care". Review. In Respiratory Care 2000;45:4-5.

Ramos-Ruiz, R., P. Penela, R.B. Penn, and F. Mayor. Analysis of the human GRK2 gene promoter. Regulation by signal transduction systems in vascular smooth muscle. Circulation 101:2083 - 2089, 2000.

Marik PE. The Clinical Features of Severe Community Acquired Pneumonia Presenting as Septic Shock. J Crit Care 2000; 15(3); 85-90.

Marik PE. Leptin, obesity and sleep apnea syndrome. Chest 2000; 118; 569-571.

Eckhart, A., S.J. Duncan, R.B. Penn, J.L. Benovic, R.J. Lefkowitz, and W.J. Koch. Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein-Coupled Receptor Kinases in the Heart. Circ Res 86:43-50, 2000.

Pascual, R.M., C.K. Billington, I.P. Hall, R.A. Panettieri, Jr., J.E. Fish, S.P. Peters, and R.B. Penn. Mechanisms underlying cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle. Am J Physiol (Lung Cell Mol Physiol) 281:L1425-L1435, 2001.

Penn, R.B., R.M. Pascual, Y.M. Kim, S.J. Mundell, V.P. Krymskaya, R.A. Panettieri Jr., and J.L. Benovic. Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. J Biol Chem 276:32648-32656, 2001.

Marik PE , Lynott J, Croxton M, Palmer E, Miller L, Zaloga GP. The Effect of Blind-Protected Specimen Brush Sampling on Antibiotics Usage in Patients with Suspected Ventilator Associated Pneumonia. J Intensive Care Med 2001;16:42-46.

Ammit, A.J., A.T. Hastie, L.C. Edsall, R.K. Hoffman, V.P. Krymskaya, S.A. Kane, S.P. Peters, R.B. Penn, S. Spiegel, and R.A. Panettieri, Jr. Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. FASEB J 15:1212-1214, 2001.

Billington, C.K., R.M. Pascual, M.L. Hawkins, R.B. Penn, and I.P. Hall. Interleukin 1b and Rhinovirus 1 sensitize adenylyl cyclase in human airway smooth muscle cells Am J Respir Cell Mol Biol 24:633-639, 2001.

Mundell, S.J., M.E. Olah, R.A. Panettieri, Jr., J.L. Benovic, and R.B. Penn. Regulation of GPCR-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and endogenous adenosine. Am J Respir Cell Mol Biol 24: 155-163, 2001.

Zalogo GP, Marik PE. Lipid modulation and systemic inflammation. Crit Care Clin 2001;17:201-218.

Penn, R.B., A.P. Pronin, and J.L. Benovic. Regulation of G protein-coupled receptor kinases. Trends Cardiovasc Med 10:81-89, 2001.

Kane GC, Sorokin R, and Holumzer C. Utilization Management Morning Report: Purpose Planning and early experience in a University Hospital Residency Program. Seminars in Medical Practice 2001; 4: 27-36.

Marik PE . Aspiration pneumonitis and aspiration pneumonia. N Engl J Med. 2001; 344:665-672

Marik PE , Weinmann A. Cytomegalovirus in “immunocompetent” critically ill, intensive care patients. Crit Care Med 2001; 29:681-682.

Mangione S. Cardiac Auscultatory Skills Of Physicians-In-Training: A Comparison Of Three English-Speaking Countries. Am J Med 2001; 110 (3) 210-216.

Hojat M, Mangione S, Nasca T, Cohen MJ, Gonnella JS, Erdman JB, Veloski J, Magee M: The Jefferson Scale of Physicians Empathy: Development and Preliminary Psychometrics Ed and Psychol Measur 61 (2) 2001:349-365

Marik PE , Zaloga GP. CPR in terminally ill patients? Resuscitation 2001; 49:99-103.

Marik PE, Oliveira EC. Influenza-Associated Pneumonia.: Description of an Outbreak. Chest 2001: 119:1717-1723.

Marik PE. The assessment of intravascular volume: A Comedy of Errors. Crit Care Med 2001; 29:1635-1636.

Mooradian NL, Caruso J, Kane GC. Increasing the time faculty spend at the bedside during Teaching Rounds. Academic Medicine 2001;76:2001

Mangione S. “Cardiac Auscultatory Skills Of Physicians-In-Training: A Comparison Of Three English-Speaking Countries." Am J Med 2001; 110: 210-216.

Lieberman P, Calhoun WJ, Panettieri RA Jr, Peters SP, Rennard SI. Asthma and irreversible lung disease. Remodeling-fact or fiction? Medical Crossfire 2001; 3:30-43.

Marik PE. Sublingual capnography: A clinical validation study. Chest 2001;120 923-927.

Marik PE , Varon J . Ventilator Associated Pneumonia: Science and Hocus-Pocus. Chest 2001; 120;702-704.

Hastie AT, Peters SP. Interactions of allergens and irritants in susceptible populations in producing lung dysfunction: Implications for future research. In: Inhaled Environmental/Occupational Irritants and Allergens: Mechanisms of Cardiovascular and Systemic Responses. (Eds.: D.B. Yeates, ) Environmental Health Perspectives 2001; 109 (Suppl 4):605-607.

Fish JE. Clinical benefits of the new generation corticosteroids. In, Modulating the Inflammatory Response in the Respiratory Tract. Hong Kong: Excerpta Medica, 2001, pp 12-15.

Marik PE , Varon J. Sepsis - State of the Art. Dis Mon 2001; 47:462-532.

Varon J, Sternbach JL, Marik PE. Cardiopulmonary Resuscitation: Current Status. Hosp Physician 2001; 37:33-40.

Chinchilli VM, Drazen J, Fish JE, Lemanske R, Lazarus S, Martin R for the Asthma Clinical Research Network. The clinical trials in the initial five-year award period of the asthma clinical research network. Controlled Clin Trials 2001; 22(Suppl):126S-134S.

Mauger E, Mauger D, Fish J, Chinchilli V, Israel . Summarizing methacholine challenges in clinical research. Controlled Clin Trials 2001; 22(Suppl):244S-251S.

Cohn JR. Let physicians heal (letter). Investors Business Daily. 2001 (Oct 12); 18:, A18.

Cohn JR. Instead of readying for terrorism, medicine compelled to study coding (letter). American Medical News. 2001 (Nov 5); 44:31-32.

Marik PE , Zaloga GP. Early enteral nutrition in acutely ill patients: A systematic review. Crit Care Med 2001; 29:2264-2270.

Cohn JR, Sataloff RT, Branton C. Response of asthma-related voice dysfunction to allergen immunotherapy: A case report of confirmation by methacholine challenge. J Voice. 2001; 15:558-560..

Lieberman, P., Calhoun, W.J., Panettieri, R.A., Jr., Peters, S.P., Rennard, S.I. Asthma and irreversible lung disease. Remodeling-fact or fiction? Medical Crossfire 3:30-43, 2001

Fish JE, Israel E, Murray JJ, Emmet A, Boone R, Yancey SW, Rickard KA. Comparison of salmeterol powder with montelukast in asthmatic patients on concomitant inhaled corticosteroid therapy. Chest 120:423-430,2001.

Leone FT, Mauger EA, Peters SP, Chinchilli VM, Fish JE, Boushey HA, Cherniack RM, Drazen JM, Fahy JV, Ford J, Israel E, Lazarus SC, Lemanske RF, Martin RM, McGeady SJ, Sorkness C, Szefler SJ, for the National Heart, Lung, and Blood Institute’s Asthma Clinical Research Network. Comparison of receiver operating characteristics of surrogate measures of asthma exacerbation. Chest 2001; 119:1027-1033.

Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF, Sorkness C, Kraft M, Fish JE, Peters SP, Martin RJ, Israel E, Ford FG, Israel E, Martin RJ, Mauger EA, Nachman SA, Spahn JD, Szefler SJ for the National Heart, Lung, and Blood Institute’s Asthma Clinical Research Network. Long-acting beta agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma. JAMA 2001; 285:2583-2593.

Lemanske RF, Sorkness CA, Mauger EA, Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Drazen JM, Fish JE, Ford JG, Peters SP, Spahn JD, Szefler SJ, for the National Heart, Lung, and Blood Institute’s Asthma Clinical Research Network. Inhaled corticosteroids reduction and elimination in patients with persistent asthma receiving salmeterol. JAMA 2001; 285:2594-2603, 2001.

Fahy JV, Boushey HA, Lazarus SC, Mauger EA, Cherniack RM, Chinchilli VM, Drazen JM, Ford JG, Fish JE, Israel E, Kraft M, Lemanske RF Jr, Martin RJ, McLean D, Peters SP, Sorkness C, Szefler SJ for the National Heart, Lung, and Blood Institute’s Asthma Clinical Research Network. Safety and reproducibility of sputum induction in asthma subjects in a multicenter study. Am J Respir Crit Care Med 2001; 163:1470-1475.

Zaloga GP, Todd N, Levit P, Marik P . Propofol-induced bronchodilation in patients with status asthmaticus.. The Internet Journal of Emergency and Intensive Care Medicine 2001, Vol 5, No 1 [http://www.icaap.org/iuicode?89.5.5.5]

American Lung Association Asthma Clinical Research Centers. [Fish J, Peters S]. The safety of inactivated influenza vaccine in adults and children with asthma. N Engl J Med 2001; 345:1529-1536.

Gaughan WJ, Fels EJ, Leone FT, McGowan T, Dunn SR, Smith J, Burke J. The initial attitudes of patients toward longer maintenance hemodialysis. Clinical Nephrology 2001; 56:150-154.

Nordstrom C, Kane GC, Wechsler R, and Farber J. Bronchial Atresia with Relapsing Pulmonary Infection. Respir Care 2001; 46:61-603.

Handley D.A., C.H. Senanayake, W. Dutczak, J.L. Benovic, T. Walle T, R.B. Penn, H.S. Wilkinson, G.J. Tanoury, R.G. Andersson, F. Johansson, and Morley J. Biological actions of formoterol isomers. Pulm Pharmacol Ther 15: 135-45, 2002.

Billington, C.K., and R.B. Penn. m3 Muscarinic acetylcholine receptor regulation in the airway. Am J Respir Cell Mol Biol 26: 269-272, 2002.

Jacobi J, Coursin D, Fraser G, Bjerke J, Chalfin D, Coplin W, Crippen D, Fontaine D, Fuchs B, Kelleher R, Marik PE, Mascia M, Riker R, Wittbrodt E, Nasraway S. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med 2002; 30:119-141

Marik PE. The diagnosis of sepsis. Not quite ready to Dump SIRS?. Crit Care Med 2002;30:706-708.

Ammit, A.J., A.L Lazaar, C. Irani, G.M. O'Neill, N.D. Gordon, Y. Amrani,, R.B. Penn, and R.A. Panettieri, Jr. TNFa-induced secretion of RANTES and IL-6 from human airway smooth muscle cells: Modulation by glucocorticoids and b-agonists. Am J Respir Cell Mol Biol 26: 465-474, 2002.

Sorokin R,Claves JL, Kane GC and Gottlieb JE. The Near-Miss Resident Conference: Understanding the Barriers to Confronting Medical Errors. Seminars in Medical Practice 2002; 5: 12-19.

Marik PE , Zaloga GP. Therapeutic sedation. Crit Care Med 2002; 30: 949-952.

Marik PE , Bowles S. Medical Aspects of Biological and Chemical Agents of Mass Destruction. J Intensive Care Med 2002; 17:147-161.

Mangione S, Kane GC, Caruso JC, Hojat M, Gonella J, Nasca TJ. Measuring Empathy in Internal Medicine Residents. Medicine Teaching 2002. Reviews:

Kane GC (Contributor). In Clinicians Pocket Reference 9th Edition. Leonard G. Gomella and Steven A. Haist Editors. McGraw Hill, New York 2002

Batra V, Kane GC, and Weibel S. PreoperativeEvaluations for patients with lung cancer undergoing thoracic surgery. Clin Pulm Medicine. 2002;9:46-52.

Khurana S, Thaker K, and Kane GC. Pulmonary Aspergillosis Part1: Hypersensitivity and Mycetomas, J Resp Dis May 2002;23:300-307.

Marik PE , Kiminyo K, Zaloga GP. Adrenal insufficiency in critically ill HIV infected patients. Crit Care Med 2002;30:1267-1273.

Marik PE, Varon J . Loop Diuretics in Acute Oliguria and prerenal states. Crit Care Shock 2002;5:64-71.

Tisherman SA, Marik PE, Ochoa,J . Promoting enteral feeding 101.Crit Care Med 2002; 30:1653-1654.

Khurana S, and Kane GC. Pulmonary Aspergillosis Part 2: Chronic Necrotizing Aspergillosis and Invasive Disease, J Resp Dis 2002;23:380-384.

Loza MJ, Peters SP, Zangrilli JG, Persussia B. Distinction between IL-13+ and IFN-g+ natural killer cells and regulation of their pool size by IL-4. Eur J Immunol 2002; 32:413-423.

Marik PE, Varon J, Trask T. The management of head trauma. Chest 2002; 122:699-711.

Marik PE. Low-Dose dopamine: A systematic review. Intensive Care Med 2002; 28:877-883.

Varon J, Marik PE. The management of head trauma in children. Crit Care Shock 2002; 5:133-143.

Martin RJ, Szefler SJ, Chinchilli VM, Kraft M, Dolovich M, Eng P, Boushey HA, Cherniack R, Craig TJ, Drazen JM, Fagan J, Fahy JV, Fish JE, Ford J, Israel E, Kunselman J. Lazarus SC, Lemanske RF Jr, Peters SP, Sorkness C, for the National Heart, Lung, and Blood Institute’s Asthma Clinical Resarch Network. Systemic effect comparisons of six inhaled corticosteroid preparations. Am J Respir Crit Care Med 2002; 165:1377-1383.

Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack R, Chinchilli VM, Drazen JM, Fish JE, Fagan J, Fahy JV, Ford J, Hurd S, Israel E, Kiley J, Kraft M, Lazarus SC, Lemanske RF, Maugher E, Peters SP, Sorkness C, for the National Heart, Lung, and Blood Institute’s Asthma Clinical Resarch Network. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol 2002; 109:410-418.

Hastie AT, Kraft WK, Nyce KB, Zangrilli JG, Musani AI, Fish JE, Peters SP. Asthmatic epithelial cell proliferation and stimulation of collagen production. Human asthmatic epithelial cells stimulate collagen type III production by human lung myofibroblasts after segmental allergen challenge. Am J Respir Crit Care Med 2002; 165:266-272.

Marik PE , Fink MP. One good turn deserves another. Crit Care Med 2002;30:2146-2148.

Varon J, Marik PE , Fromm RE. Intravenous 2ß or No 2ß - That is the Question! Chest 2002; 122:1116-1117.

Marik PE. NF-?B inhibition in Sepsis: Steroids vs Specific NF-?B inhibitors? Crit Care Med 2002;30:2393-2394.

Patkar A, Sterling R, Leone FT, Lundy A, Weinstein S. Relationship between tobacco smoking and medical symptoms among cocaine-, alcohol-, and opiate-dependent patients. American Journal on Addictions 2002; 11:209-215.

Batra V, Patkar A, Weibel S, Pincock G, Leone FT. Public health implications of voters’ attitudes regarding statewide tobacco policy. Chest 2002; 122:295-298.

Patkar AA, Lundy A, Leone FT, Weinstein S, and Gottheil E. Tobacco and alcohol use and medical symptoms among cocaine dependent persons. Substance Abuse 2002; 23:105-113.

Marik PE , Varon J, Fromm RM. The management of severe asthma. J Emerg Med 2002; 23:257-268.

Varon J, Marik PE . Clinical Information Systems and the Electronic Medical Record in the Intensive Care Unit. Curr Opin Crit Care 2002; 8:616-624.

Sorokin R, Claves JL, Kane GC, Gottlieb JE. The near-miss resident conference: Understanding the barriers to confronting medical errors. Seminars in Medical Practice 2002; 5: 12-19.

Musani A, Pascual RM, Peters SP. Asthma. In: Manual of Allergy and Immunology, 4th Ed.: (Eds.: D.C. Adelman, T.B. Casale, J. Corren). Lippincott Williams & Wilkins, Philadelphia, PA, pp. 93-137, 2002.

Varon J, Marik PE. Self-assessment in Critical Care Medicine. Pulmonary review questions. Hospital Physician 2002; June, pg 33-34.

Marik P , Varon J, Fromm RE. Goal-directed therapy in sepsis: Fact or fiction. Crit Care Shock 2002;5:31-32

Chanin K, Fong E, Marik P , Fromm RE, Varon J. Neurologic Outcome after Cardiac Arrest With The Use of Mild Therapeutic Hypothermia. Crit Care Shock 2002; 5:190-192.

Peters SP. The distal lung in asthma: An under appreciated but emerging area in asthma pathogenesis and treatment. Perspective in MD Consult, January 16, 2002.

Batra V, Peters SP. Leukotriene modifiers as monotherapy for asthma. Harrison’s Online 2002.

Batra V, Niazi S, Peters SP. Persistent asthma: What approach is best? J Respir Dis 2002; 23: 330-340.

Leone FT, Weibel, S. Treating tobacco use in Pennsylvania: The expanding scope of Medical Assistance. Keystone Physician 2002; 54:9-10.

Batra V, Patkar A, Weibel S, Leone FT. Tobacco smoking as a chronic disease: Notes on prevention and treatment. Primary Care: Clinics in Office Practice 2002; 29:1-20.

Leone FT. A Question of Intent: A Great American Battle with a Deadly Industry by David Kessler, MD. Book Review and Commentary. Journal of Applied Psychoanalytic Studies 2002; 4:451-453.

Zangrilli, JG. Regulation of eosinophil viability by cytokines. Am J Respir Cell Mol Biol 2002; 26:388.

Ahuja, R, Weibel S, Leone FT. Lung Cancer: The Oncologist’s Role in Smoking Cessation. Seminars in Oncology, vol. 30, (1) Feb. 2003, 94-103

Maust HA. Foroozan R. Sergott RC. Niazi S Weibel S. Savino PF. Use of methotrexate in sarcoid-associated optic neuropathy. Ophthalmology. 110(3):559-63, March 2003

Marik PE, Zaloga GP. Adrenal insufficieny in septic shock. Crit Care Med 2003; 31:141-145.

Marik PE. The Optimal End Point of Resuscitation in Trauma Patients. Crit Care 2003;7:19-20.

Pascual RM, Awsare BK, Farber SA, Panettieri RA Jr, Peters SP, Penn RB. Regulation of phospholipase A2 by interleukin-1 in human airway smooth muscle. Chest. 2003 Mar;123(3 Suppl):433S-4S.

Awsare B, Peters SP. Status asthmaticus. In: Current Therapy in Allergy, Immunology and Rheumatology, 6th Ed. (Eds.: L.M. Lichtenstein, W.W. Busse, R.S. Geha). Mosby, Inc., Philadelphia, PA.

Marik PE , Bankov A. Sublingual Capnometry Versus Traditional Markers of Tissue Oxygenation in Critically Ill Patients. Crit Care Med 2003; 31:818-822.

Zaloga GP, Marik PE . Sulfite-Induced Propofol Oxidation: A Cause For Radical Concern. Crit Care Med 2003; 31:981-983.

Sternbach GL, Varon J, Marik PE. Defibrillation. Crit Care Shock 2003;6:50-54.

Niazi S, Batra V, Awsare B, Zangrilli JG, Peters SP. Allergic Inflammation: Initiation, Progression and Resolution. In: Allergy: Principles and Practice, 6th Ed. (Eds.: N.F. Adkinson, Jr., W.W. Busse, C.E. Reed, E.F. Ellis, J.W. Yunginger). Mosby, St. Louis.

Leone FT, Fish JE, Szefler S, West S, and the writing committee for the expert panel on inhaled corticosteroid use. Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma. Chest. 2003 Dec;124(6):2329-40

Varon J, Gonzalez A, Sternbach GL, Marik PE. Tracheal rupture: Airway catastrophe associated with intubation. Crit Care Shock 2003;6: 163-166.

Marik PE , Pinsky, MR. Death by total parenteral nutrition. Intensive Care Med 2003; 29:867-869.

Marik PE , Kaplan D. Aspiration pneumonia and dysphagia in the elderly. Chest 2003; 124:328-336.

Batra V, Patkar A, Berrettini W, Weinstein S, Leone FT. Genetic determinants of smoking. Chest. 2003 May;123(5):1730-9

Khurana S, Batra V, Patkar A, Leone F. Twenty-first Century Tobacco Use: It’s Not Just a Risk Factor Anymore. Respiratory Medicine. 2003 Apr;97(4):295-301.

Patkar AA, Thornton C, Weinstein S, Leone FT. Nicotine dependence and treatment-outcome among African-American cocaine dependent patients. Nicotine and Tobacco Research. 2003 Jun;5(3):411-8.

Varon J, Marik PE. The management of hypertensive crisis. Critical Care 2003; 7:374-384.

Marik PE. Aliens, Anaerobes and the lung. Intensive Care Med 2003; 29: 1035-1037.

Marik PE , Doyle H, Varon J. Is obesity protective during critical illness. Crit Care Shock 2003;6:156-162.

Zaloga GP, Roberts P, Marik PE. Feeding the hemodynamically unstable patient: A critical evaluation of the evidence. Nutr Clin Pract 2003;18:285-293.

Patkar A, Hill K, Batra V, Vergare M, Leone FT. A comparison of smoking habits among medical and nursing students. Chest 2003; 124: 1415-1420.

Aran F, Varon J, Marik PE. Hyperbaric oxygen therapy in carbon monoxide poisoning: How far out? Crit Care Shock 2003;6:65-66.

Varon J, Marik PE. Managing acute severe asthma: What therapies to try and when. J Resp Dis 2003;24:67-76.

Patkar A, Weinstein S, Berrettini W, Lundy A, Gopalakrishnan R, Vergare M, Leone FT. Differences in platelet serotonin transporter sites between African-American tobacco smokers and nonsmokers. Psychopharmacology 2003; 166: 221-227.

Dial, EM. and Kane, GC. Rounded Atelectasis: An Important Manifestation of Asbestos-related Pleural Disease. In Chest Film Clinic-Why the abnormal findings in this man without symptoms? J Respiratory Diseases 2003; 24:537-539.

Iglesias JI, Marik PE , Levine JS. Elevated Serum Levels of the Type I and Type II Receptors for TNF-a as Predictive Factors for Acute Renal Failure in Patients with Septic Shock. Am J Kidney Dis 2003; 41:62-75.

Varon J, Marik PE . Treatment of Cardiac Arrest with Automatic External Defibrillators: Impact on Health Outcomes. Am J Cardiovasc Drugs 2003; 3:265-270.

Mani A, and Kane GC. Mycobacterium avium intracellulare in the immunocompetent host. Hospital Practice: Pulmonary Board Review 2003; 11:2-12.

Fields SK, Hojat M, Gonnella J, Magione S, Kane G, and Magee M. Comparisons of Nurses and Physicians on an Operational Measure of Empathy Evaluations and the Health Professions Volume 27, Number 1, pages 80-94, March 2004.

Lunenfeld E, Kane GC. Methemoglobinemia: sudden dyspnea and oxyhemoglobin desaturation after esophagoduodenoscopy. Respiratory Care 2004 Aug;49(8):940-2

Marik PE. Unraveling the Mystery of Adrenal Failure in the Critically Ill. Crit Care Med 2004: 32:596-597.

Marik PE , Raghavan M. Stress-Hyperglycemia, Insulin and Immunomodulation in Sepsis. Intensive Care Med 2004; 30:748-756.

Marik PE, Zaloga GP. A meta-analysis of Parenteral Nutrition vs Enteral Nutrition in Acute Pancreatitis. BMJ 2004, 328:1407-1409.

Zaloga GP, Siddiqui R, Terry C, Marik PE. Arginine: Mediator or modulator of sepsis? Nutr Clin Pract 2004; 19:201-215.

Marik PE , Varon J. Management of status epilepticus. Chest 2004; 126:582-591.

Marik PE. Renal dose norepinephrine!.Chest 2004; 126:335-337.

Marik PE. Propofol: Therapeutic indications and side effects. Curr Phar Design 2004; 10: 3639-3649.

Marik PE. Monitoring Therapeutic Interventions Critically Ill Patients. Nutr Clin Pract 2004; 19:423-432.

Wood, KA, Marik PE. ICU Care at the End of Life. Chest 2004; 126:1403-1405.

Raghavan M, Marik PE. Anemia, Allogenic Blood Transfusion, and Immune-modulation in the Critically Ill. Chest 2005; 127:295-307.

Varon J, Marik PE. Traumatic brain in children: Self assessment in Critical Care Medicine. Hospital Physician, January 2004, 17-18

Peer Reviewed Papers (in press)

Gill J, Diamond J, Leone FT, Pellini B, Wender R. Do physicians follow national guidelines for tobacco counseling?: A statewide study. Delaware Medical Journal.

Patkar A, Batra V, Mannelli P, Evers-Casey S, Vergare M, Leone FT. Medical symptoms associated with tobacco smoking with and without marijuana use among crack cocaine abusers. American Journal on Addictions.

Kane GC. Preoperative Evaluation of Patients with Pulmonary Disease. Hospital Practice: Pulmonary Board Review 2004; Volume 11, Part 4, 2-11(in press)

Patkar A, Gopalkrishnan R, Lundy A, Certa K, Leone FT, Weinstein S. Tobacco smoking and negative symptoms in schizophrenia. Journal of Nervous and Mental Diseases. In press.

Campbell R, Lopez, Marik PE , Severe Autoimmune Hemolytic Anemia Treated by Paralysis, Induced Hypothermia and Splenic Embolization. Chest 2004 (in press).

Beaulieu Y, Marik PE. Echocardiography in the ICU. Part 1.Chest 2004; (in press).

Beaulieu Y, Marik PE. Echocardiography in the ICU. Part 2.Chest 2004; (in press).

Marik, PE. Propofol: An Immuno-modulating Agent. Pharmacology 2004 (in press).

Murray H, Marik PE. Etomidate, Sepsis and Stress Steroids: The Dilemma. Chest 2005 (in press)

Wood K, Marik PE. The genetics of pneumonia. Current Respiratory Medicine Reviews 2005 (in press).

Marik PE. Regional Carbon Dioxide Monitoring to Assess the Adequacy of Tissue Perfusion. Current Opinion in Critical Care 2005; (in press)

Huerta-Alardín AL, Varon J, Marik PE. Rhabdomyolysis: An Overview for Clinicians. Critical Care 2004;

Varon J, Marik PE. Noninvasive positive pressure ventilation. Critical Decisions in Emergency Medicine 2005; (in press)

Raghavan M, Marik PE. Management of Sepsis during the early Golden hours.” (submitted).

Marik PE , Gayowski T, Starzl TE. The Hepato-Adrenal Syndrome: A Common yet Unrecognized Condition.(submitted).

Marik PE , Wood K, Starzl TE. The Course of Type 1 Hepato-Renal Syndrome Post Liver Transplantation. (Submitted).

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