Jay S. Schneider, PhD

Contact Dr. Schneider

1020 Locust Street.
Suite 521
Philadelphia, PA 19107

(215) 503-0370
fax

Research and Clinical Interests

Publications

Most recent Peer-reviewed Publications

1. Effects of memantine and galantamine on cognitive performance in aged rhesus macaques
2. Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates
3. Rearing environment, sex and developmental lead exposure modify gene expression in the hippocampus of behaviorally naïve animals
4. Influence of developmental lead exposure on expression of DNA methyltransferases and methyl cytosine-binding proteins in hippocampus
5. A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients
6. Levodopa improves motor deficits but can further disrupt cognition in a macaque parkinson model
7. Sex and rearing condition modify the effects of perinatal lead exposure on learning and memory
8. Effects of developmental lead exposure on the hippocampal transcriptome: Influences of sex, developmental period, and lead exposure level
9. Impaired spatial working memory learning and performance in normal aged rhesus monkeys
10. Differential effect of postnatal lead exposure on gene expression in the hippocampus and frontal cortex
11. Behavioral toxicology of cognition: Extrapolation from experimental animal models to humans. Behavioral toxicology symposium overview
12. Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
13. Sex-based differences in gene expression in hippocampus following postnatal lead exposure
14. Effects of the alpha-2 adrenoceptor agonist guanfacine on attention and working memory in aged non-human primates
15. Functional significance of aldehyde dehydrogenase ALDH1A1 to the nigrostriatal dopamine system
16. Attention, executive functioning and memory in normal aged rhesus monkeys
17. Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates
18. Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition
19. The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures
20. Predictors of cognitive outcomes in early Parkinson disease patients: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience

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