Hui Zhang, PhD

Contact Dr. Zhang

900 Walnut Street
Room 422
Philadelphia, PA 19107

(215) 503-7213

Research and Clinical Interests
Research in my laboratory aims to elucidate the pathogenic mechanisms of Parkinson's disease and Schizophrenia at the molecular, cellular and synaptic levels

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Publications

Most recent Peer-reviewed Publications

1. Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain
2. Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease In Vivo
3. Dopamine release at individual presynaptic terminals visualized with FFNs.
4. Dopamine release at individual presynaptic terminals visualized with FFNs
5. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals
6. Repeated Exposure to Methamphetamine Causes Long-Lasting Presynaptic Corticostriatal Depression that Is Renormalized with Drug Readministration
7. Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
8. Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons
9. Frequency-dependent modulation of dopamine release by nicotine
10. Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals
11. Erratum: Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing (Journal of Neurochemistry (2003) 87 (1284-1295))
12. Regulation of the Development of Mesencephalic Dopaminergic Systems by the Selective Expression of Glial Cell Line-Derived Neurotrophic Factor in Their Targets
13. Dopamine Neurons Mediate a Fast Excitatory Signal via Their Glutamatergic Synapses
14. Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing
15. Glutamate Spillover in the Striatum Depresses Dopaminergic Transmission by Activating Group I Metabotropic Glutamate Receptors
16. The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate
17. Contribution of the β subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor
18. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit
19. Lectin and ion channel
20. Cation selectivity of channels formed at planar lipid bilayer by Pinellia ternata lectin

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