Thomas Jefferson University - Raymond F. Regan
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Raymond F. Regan
Emergency Medicine
Thomas Jefferson University
Jefferson Medical College
Department of Emergency Medicine
Professor
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Publications
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- 1. Abraham E. Regan RF. The effects of hemorrhage and trauma on interleukin-2 production. Archives of Surgery, 1985; 120:1341-1344.
- 2. Abraham E. Regan RF. Chang YH. Lack of effect of exogenous recombinant interleukin-2 on trauma-induced abnormalities in lymphocyte proliferation. Critical Care Medicine, 1986; 14:847-851.
- 3. Regan RF, Choi DW. Glutamate neurotoxicity in spinal cord cell culture. Neuroscience, 1991; 43: 585-591.
- 4. Regan RF, Renn KE, Panter, SS. NMDA neurotoxicity in murine cortical cell cultures is not attenuated by hemoglobin or inhibition of nitric oxide synthesis. Neuroscience Letters, 1993; 153:53- 56.
- 5. Regan RF, Panter SS. Neurotoxicity of hemoglobin in cortical cell culture. Neuroscience Letters, 1993; 153:219-222.
- 6. Regan RF, Choi, DW. The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture. Brain Research, 1994; 633:236-242.
- 7. Panter SS, Vandegriff KD, Yan PO, Regan RF. Assessment of hemoglobin dependent neurotoxicity: alpha-alpha crosslinked hemoglobin. Biomaterials, Artificial Cells, and Immobilization Biotechnology,1994; 22:399-413.
- 8. Regan RF, Panter SS. Traumatic neuronal injury in cortical cell culture is attenuated by 21- aminosteroids. Brain Research, 1995; 682:144-150.
- 9. Regan RF, Panter SS, Witz A, Tilly JL, Giffard RG. Ultrastructure of excitotoxic neuronal death in murine cortical culture. Brain Research, 1995; 705:188-198.
- 10. Regan RF. The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons. Neuroscience Letters, 1996; 213:9-12.
- 11. Regan RF, Panter SS. Hemoglobin potentiates excitotoxic neuronal injury in cortical cell culture. Journal of Neurotrauma, 1996; 13:223-231.
- 12. Regan RF, Guo YP. Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures. Brain Research, 1997; 764:133-140.
- 13. Regan RF, Jasper E, Guo YP, Panter SS. The effect of magnesium on oxidative neuronal injury in vitro. Journal of Neurochemistry, 1998; 70:77-85.
- 14. Regan RF, Guo YP. Toxic effect of hemoglobin on spinal cord neurons in culture. Journal of Neurotrauma, 1998; 15:645-653.
- 15. Regan RF, Guo, YP Extracellular reduced glutathione increases neuronal vulnerability to combined chemical hypoxia and glucose deprivation. Brain Research, 1999; 817:145-150.
- 16. Regan RF, Guo YP. Potentiation of excitotoxic injury by high concentrations of extracellular reduced glutathione. Neuroscience, 1999; 91:463-470.
- 17. Regan RF, Guo YP Kumar N. Heme oxygenase-1 induction protects cortical astrocytes from hemoglobin toxicity. Neuroscience Letters, 2000; 282:1-4.
- 18. Regan RF, Guo YP. Magnesium deprivation decreases cellular glutathione and induces oxidative neuronal death. Brain Research, 2001; 890:177-183.
- 19. Regan RF, Wang Y, Ma X, Guo YP. Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures. Journal of Neurochemistry, 2001, 79:545-555.
- 20. Regan RF, Kumar N, Gao F, Guo YP. Increased ferritin synthesis protects cortical astrocytes from heme-mediated oxidative injury. Neuroscience, 2002, 113:985-994.
- 21. Regan RF, Rogers B. Delayed treatment of hemoglobin neurotoxicity. Journal of Neurotrauma, 2003, 20:111-120.
- 22. Goldstein L, Teng Z, Zeserson E, Patel, M., Regan RF. Hemin induces an iron-dependent, oxidative injury on human neuron-like cells. Journal of Neuroscience Research, 2003, 73:113-121.
- 23. Rogers B, Yakopson V, Teng Z, Regan RF. Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity. Free Radical Biology and Medicine, 2003, 35:872-881.
- 24. Vanderveldt GM, Regan RF. The neurotoxic effect of sickle cell hemoglobin. Free Radical Research, 2004, 38:431-437.
- 25. Chen J, Regan RF. Heme oxygenase-2 gene deletion increases astrocyte vulnerability to hemin. Biochemical and Biophysical Research Communications, 2004, 318:88-94.
- 26. Regan RF, Chen J, Benvenisti-Zarom L. Heme oxygenase-2 gene deletion attenuates oxidative stress in neurons exposed to extracellular hemin. BMC Neuroscience, 2004, 5:34.
- 27. Teng ZP, Chen J, Chau LY, Galunic N, Regan RF. Adenoviral transfer of the heme oxygenase-1 gene protects striatal astrocytes from heme-mediated oxidative injury. Neurobiology of Disease, 2004, 17:179-187.
- 28. Rattan S, Regan RF, Patel CA, De Godoy MA. Nitric oxide not carbon monoxide mediates nonadrenergic noncholinergic relaxation in the murine internal anal sphincter. Gastroenterology. 2005,129:1954-66.
- 29. Chen J, Regan RF. Increasing expression of endogenous heme oxygenase-1 by proteasome inhibition protects astrocytes from heme-mediated oxidative injury. Current Neurovascular Research, 2005; 2:189-96.
- 30. Benvenisti-Zarom L, Chen J, Regan RF. The oxidative neurotoxicity of clioquinol. Neuropharmacology, 2005, 49:687-94.
- 31. Qu Y, Chen J, Benvenisti-Zarom L, Ma X, Regan RF. Effect of targeted deletion of the heme oxygenase-2 gene on hemoglobin toxicity in the striatum. Journal of Cerebral Blood Flow and Metabolism, 2005, 25:1466-75.
- 32. Chen-Roetling J, Benvenisti-Zarom L, Regan RF. Cultured astrocytes from heme oxygenase-1 knockout mice are more vulnerable to heme-mediated oxidative injury. Journal of Neuroscience Research, 2005, 82:802-810.
- 33. Parfenova H, Basuroy S, Bhattacharya S, Tcheranova D, Qu Y, Regan RF, Leffler CW. Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection. American Journal of Physiology Cell Physiology, 2006, 290:C1399-410.
- 34. Benvenisti-Zarom L, Chen-Roetling J, Regan RF. Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury. Neuroscience Letters, 2006, 398:230-234.
- 35. Goodman AI, Chander PN, Rezzani R, Schwartzman ML, Regan RF, Rodella L, Turkseven S, Lianos EA, Dennery PA, Abraham NG. Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction. Journal of the American Society of Nephrology, 2006, 17:1073-81.
- 36. Chen-Roetling J, Regan RF. Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin. Biochemical and Biophysical Research Communications, 2006, 350:233-237.
- 37. Basuroy S, Bhattacharya S, Tcheranova S, Qu Y, Regan RF, Leffler CW. Parfenova H. HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells. American Journal of Physiology Cell Physiology, 2006, 291:C897-908.
- 38. Qu Y, Chen J, Benvenisti-Zarom L, Regan RF. Oxidative injury after experimental intracerebral hemorrhage is attenuated in heme oxygenase-2 knockout mice. Journal of Neurosurgery, 2007, in press.
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Individual Expertise profile of
Raymond F. Regan, Copyright © Raymond F. Regan.
Last Updated
by Admin
: Wednesday, January 24, 2007 12:17:45 PM
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