Institutional Animal Care & Use Committee (IACUC)
Policies, Guidelines, & Procedures
This is the set of official policies, guidelines and SOPs that cover the use research animals here at the University. The IACUC refers to these in its oversight role.
IACUC Policies, Guidelines, & SOPs
The IACUC maintains a set of policies, guidelines, and SOPs that govern the use of research animals at the University. Policies are rules that are reviewed and approved by the IACUC. If applicable, they must be followed unless there is scientific or veterinary justification not to. Guidelines are recommendations that investigators can use as an aid when describing a procedure in a protocol. They can not, however, be referenced in place of a description of a procedure. SOPs are descriptions of common animal use procedures. They are reviewed and approved by the IACUC and can be referenced, in place of a description of a procedure, in a protocol.
Policies
If applicable, these policies must be followed unless a scientific or veterinary justification is provided in the animal use protocol. In this regard, they are treated by the IACUC as rules or regulations.
General Policies
Animal Welfare Policies
- Pain and Distress Policy
- Movement and Transportation of Research Animals
- Feeding Rodents on the Cage Floor
- Toe-clipping for Identification of Rodents
Research Policies
- Anesthesia, Analgesia, and Tranquilization
- Survival Surgical Procedures in Rabbits and Higher Mammals
- Post-Operative Monitoring of Research Animals
- Survival Surgical Procedures and Post-Operative Monitoring of Research Animals
- Survival Surgical Procedures and Post-Operative Care in Rodents
- Maintenance of Fluid Homeostasis in Rodents
- Use of Complete Freund's Adjuvant
- Utilization of Rodents in Experimental Neoplasia and Ascites Production
- Blood Collection
- Overcrowding of Rodents
- Induction of Experimental Allergic Encephalomyelitis (EAE)
- Production of Monoclonal Antibodies in Laboratory Mice
- Housing of Rodents
Health & Safety Policies
- Occupational Health and Safety Program for Personnel with Significant Animal Exposure
- Safety Procedures for Handling and Care of Animals Exposed to Human Origin Tissue, Cells or Tumors
- Response Procedures to Animal Bites, Scratches and Related Injuries
- Management of Cercopithecine Herpesvirus 1 (formerly Herpes-virus simiae or "B" Virus) Exposures
- Safe Practices Using the Neurotoxin MPTP in the Animal Facility
Training Policies
Animal Protocol Policies
Compliance & Reporting Policies
- Enforcement of Rules and Regulations
- Policy for Reporting and Investigating Animal Welfare Concerns at Thomas Jefferson University
- Link to University Policy 110.02 - Responding to Alleged Misconduct in Research
Guidelines
These guidelines are provided as an aid to investigators when describing a procedure in an animal use protocol. They should not be referenced in place of a description of a procedure but investigators are free to use them in their descriptions.
- Alternatives to Animal Use and Painful Procedures
- Euthanasia Guidelines
- See also: Report of the AVMA Panel on Euthanasia
- Guidelines for the Care and Use of Laboratory Animals in Patient Care Areas
- U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research and Training
- Guidelines for the Safe Use of Isoflurane in Animal Research
- Rodent Tumor Monitoring Guidelines
SOPs
The IACUC has approved a number of SOPs for common animal use procedures. When writing an Animal Use Protocol, one can refer to these instead of writing out a description of the procedure. If you wish to reference these in your protocol, deviations from these SOPs should be addressed and justified when submitting your proposal to the IACUC for review.
- Breeding of Mice
- AIMS Tattooing System
- Genotyping Using Tail Tissue
- Retro-Orbital Bleeding
- Tail Vein Injection
- Small Animal Molecular Imaging Facility
- Optical Imaging
- Appendix A Jefferson Alumni Hall
- Appendix B College Building
- Appendix C Bluemle Life Sciences Building
- Avian Embryo Euthanasia
- Transportation and Handling of Research Animals for Irradiation

