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The Division of Infectious Diseases assists in the management of infectious disease problems throughout Thomas Jefferson University Hospital and its affiliates. The division also has active basic and clinical research programs examining the epidemiology, pathogenesis and treatment of infectious diseases. There are 11 full-time faculty (both clinical and research) who participate in divisional, house staff, departmental and University conferences and courses.
The infectious diseases consultation service sees 70 to 90 in-patients a month on all hospital services. Residents rotating on the consultation service are involved in the management of a wide variety of clinical infectious disease problems. Emphasis is placed on a logical approach to evaluating possible infections, decision making in diagnosis and therapy of infected patients and familiarity with the use of antibiotics. Divisional faculty and fellows lead an infectious disease out-patient clinic that meets weekly. Educational activities include weekly divisional and inter-city infectious disease conferences, a monthly case conference for medical house staff, monthly divisional research conferences and journal club conferences.
A diverse patient population, collaboration with the clinical Microbiology laboratory, the Department of Microbiology and numerous divisional studies allow for many opportunities to pursue basic and clinical research activities including:
- Gene therapy for HIV-1 infection.
- Molecular control mechanisms of HIV-1 replication.
- Pathogenesis of HIV-1 infections of the brain
- Molecular mechanisms of HIV-1 maternal-fetal transmission.
- Cellular immune response to adenovirus; and hepatitis C virus.
- Immune modulation to HIV-1 infection.
- Role of cytokine elaboration in progression of HIV-1 infection.
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