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JCGS
Home > Academic Programs > Ph.D.
Programs > Immunology & Microbial
Pathogenesis > Faculty
Program Faculty
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Abraham, Ph.D., David
Phone: 215-503-8917
Email: David.Abraham@jefferson.edu
Research Interests: Parasite Immunology
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Alugupalli, Ph.D., Kishore
Phone: 215-503-4554
Email: Kishore.Alugupalli@mail.jci.tju.edu
Research Interests: B Cell Memory; Innate Immunity; Bacterial Pathogenesis
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Arafat,, Hwyda
Phone: (215) 955-6383
Email: HWYDA.ARAFAT@jefferson.edu
M.D., Ain Shams Medical School, Cairo, Egypt
M.S., Ain Shams Medical School, Cairo, Egypt: Anatomy
Ph.D., University of Medicine and Dentistry of New Jersey and Ain Shams Medical School: Cell Biology/Immunology.
My laboratory is currently investigating the molecular mechanisms involved in the regulation of oxidative stress and inflammation signaling in two pancreatic diseases, type 1diabetes and pancreatic cancer.
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Buchberg, Ph.D., Arthur M.
Phone: 215-503-4533
Email: buchberg@mail.jci.tju.edu
Research Interests: Cancer Genetics, Genetics of Cancer Susceptibility
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Calabretta, M.D., Ph.D., Bruno
Phone: (215) 503-4522
Email: Bruno.Calabretta@mail.tju.edu
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Calkins, Ph.D., Catherine
Phone: 215-503-7950
Email: Catherine.Calkins@jefferson.edu
Research Interests: Cellular Immunology, centered on autoimmunity and anti-viral responses
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Campbell, Kerry S.
Phone: 215-728-7761
Email: kerry.campbell@fccc.edu
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Daniel, M.D., Ph.D. , René
Phone: 215-503-5725
Email: Rene.Daniel@jefferson.edu
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Dietzschold, D.V.M., Bernhard
Phone: (215) 503-4692
Email: Bernhard.Dietzschold@jefferson.edu
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Eisenlohr, V.M.D., Ph.D., Laurence C.
Phone: 215-503-4540
Email: Laurence.Eisenlohr@mail.jci.tju.edu
Research Interests: Antigen Processing/Presentation and T Cell Responses
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Flomenberg, M.D., Neal
Phone: (215) 955-4367
Email: Neal.Flomenberg@jefferson.edu
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Flomenberg, M.D., Phyllis
Phone: (215) 503-2170
Email: Phyllis.Flomenberg@jefferson.edu
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Hardy, Ph.D., Richard R.
Phone: 215-728-2469
Email: rr_hardy@fccc.edu
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Hooper, Ph.D., D. Craig
Phone: (215) 503-1774
Email: Douglas.Hooper@jefferson.edu
Research Interests: Neuroimmunology, inflammation and free radicals.
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Manser, Ph.D., Timothy L.
Phone: 215-503-4672
Email: manser@mail.jci.tju.edu
Research Interests: Regulation of the Development of B Cell Immunity and Autoimmunity
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McGettigan, Ph.D., James P
Phone: 215-503-4629
Email: james.mcgettigan@jefferson.edu
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McKenzie, M.D., Ph.D., Steven E
Phone: 215-955-3900
Email: Steven.McKenzie@jefferson.edu
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Paumet, Fabienne
Phone: 215-503-8567
Email: Fabienne.Paumet@jefferson.edu
MOLECULAR MECHANISMS OF PHAGOCYTOSIS: how do pathogens subvert this process?
*Unraveling membrane trafficking involved in the phagocytic pathway and its regulation
*How do bacteria interfere with the host phagocytic system to escape lysosomal degradation?
CHARACTERIZATION OF EUKARYOTIC MEMBRANE FUSION MACHINERY
*Identification and characterization of primitive membrane fusion machineries (similar to SNARE proteins?)
*Characterization of the specificity of fusion encoded in the SNARE proteins
*Characterization of intramolecular SNARE regulation
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Pestell, M.D., Ph.D., Richard G
Phone: 215-503-5692
Email: director@kimmelcancercenter.org
Professor of Oncology and Medicine
Director, Kimmel Cancer Center
Dr. Pestell completed his M.D. (1981) and Ph.D. degrees in
Australia. He undertook post doctoral and clinical training in
Hematology/Oncology and Endocrinology and continued research at
Harvard University and served as Clinical fellow at Massachusetts
General Hospital.
Major contributions are to the area of cell-cycle control and targeted cancer therapies. These
include the discovery that cyclins are direct transcriptional targets of oncogenic and tumor suppressor signals and
that cyclin expression is rate-limiting for oncogene-induced tumor growth in vivo. His laboratory pioneered the application of tissue-specific inducible transgenics and
the development of gene-targeted and transgenic mice providing superior model of human cancer. His patent of
light activated gene therapy, which allows single cell targeting of a payload, is broad including all genes in the
human genome.
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Rahman, S.M. Ziaur
Phone: 215-503-9043
Email: zrahman@mail.jci.tju.edu
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Rall, Ph.D., Glenn F.
Phone: 215-728-3617
Email: glenn.rall@fccc.edu
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Rodeck, M.D., Ulrich
Phone: 215-503-5622
Email: Ulrich.Rodeck@mail.jci.tju.edu
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Root, M.D., Ph.D., Michael
Phone: 215-503-4564
Email: mroot@mail.jci.tju.edu
M.D., Harvard Medical School, Boston, MA 1997. Ph.D., Harvard University, Cambridge, MA 1997. Structure and function of glycoproteins involved in viral and cell-cell membrane fusion; design of viral entry inhibitors and immunogens for vaccine development.
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Rostami, Abdolmohamad
Phone: 215-955-1234
Email: A.M.Rostami@jefferson.edu
My research focuses on...
Multiple Sclerosis is an autoimmune disease of the central nervous system
that affects over 400,000 Americans and over 2 million worldwide. My
research focuses on the pathogenesis of multiple sclerosis using the animal
model of this disease, experimental autoimmune encephalomyelitis (EAE). At
the present, we are focusing on three main areas:
1) The role of IL-12/IL-17/IL-23 axis in the pathogenesis of EAE and
multiple sclerosis.
2) The effect of the Bowman-Birk protease inhibitor on the course of EAE.
This study has the potential to provide a novel, safe, and effective therapy
for multiple sclerosis.
3) Mechanisms of intravenous tolerance in EAE.
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Sato, M.D., Ph.D., Takami
Phone: (215) 955-8875
Email: Takami.Sato@mail.tju.edu
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Schnell, Ph.D., Matthias J.
Phone: 215-503-4634
Email: Matthias.Schnell@jefferson.edu
Research Interests: viral pathogenesis, HIV-1, and vaccines development
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Scott, Ph.D., Charles P.
Phone: 215-503-4569
Email: cscott@mail.jci.tju.edu
Ph.D., University of Pennsylvania, Philadelphia, PA, 1997. Combinatorial drug discovery; rational drug design; chemical genomics of
host-pathogen interactions and cancer; mechanism of drug and hormone
resistance in breast cancer; mechanism of TCL1 oncogene in CLL.
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Sigal, Luis
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Siracusa, Ph.D., Linda D.
Phone: 215-503-4536
Email: Siracusa@mail.jci.tju.edu
Molecular genetics and biology of hair and skin development and disease processes; identification and characterization of cancer susceptibility genes.
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Snyder, Ph.D., Christopher M.
Phone: 215-503-2543
Email: Christopher.Snyder@jefferson.edu
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Strayer, M.D., Ph.D., David S.
Phone: (215) 503-1087
Email: David.Strayer@jefferson.edu
Aids; Bioterrorism; Botulinum Toxin; Cell Biology; Cell Growth Regulation; Complementary Dna; Dna Footprinting; Gene Expression; Gene Induction Repression; Gene Therapy; Genetic Promoter Element; Genetics; Molecular Cloning; Nucleic Acid Sequence; Poxviruses; Site Directed Mutagenesis; Sv40; Tissue Cell Culture; Transcription Factor; Transfection; Tumor Suppressor Gene; Viral Genetics; Virology
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Sykulev, M.D., Ph.D, Yuri K.
Phone: 215-503-4530
Email: ysykulev@mail.jci.tju.edu
Research Interests: Immunobiology of cytotoxic lymphocytes
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Taraschi, Ph.D., Theodore F.
Phone: (215) 503-5020
Email: Theodore.Taraschi@jefferson.edu
Ph.D., Rutgers University, Chemistry, 1980. Vice Chair for Education, Department of Pathology, Anatomy & Cell Biology. Program Director, Cell & Developmental Biology Program
Areas of research include:
1) Elucidation of parasite protein trafficking pathways from intracellular parasites to the erythrocyte cytosol and host cell membrane.
2) Determinantion of the mechanism of hemoglobin uptake and transport by intraerythrocytic parasites.
3) Characterization of parasite DNA repair pathways (e.g. base excision and mismatch repair). Continued identification of the cellular components of these trafficking pathways to gain a better understanding of transport mechanisms in malaria-infected erythrocytes.
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Wagner, M.D., John L.
Phone: 215-955-1384
Email: john.l.wagner@mail.tju.edu
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Waldman, M.D., Ph.D., Scott A.
Phone: (215) 955-6086
Email: Scott.Waldman@jefferson.edu
Professor; Ph.D., Thomas Jefferson, 1980; M.D., Stanford, 1987. Molecular mechanisms of signal transduction, with emphasis on receptor-effector coupling and post-receptor signaling mechanisms; molecular mechanisms underlying tissue-specific transcriptional regulation; translation of molecular signaling mechanisms to novel diagnostic and therapeutic approaches to patients with cancer.
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Wiest, Ph.D., David L
Phone: 215-728-2966
Email: DL_Wiest@FCCC.edu
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Zhang, M.D., Ph.D., Hui
Phone: 215-503-0163
Email: Hui.Zhang@jefferson.edu
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Zhang, Ph.D., Jianke
Phone: 215-503-4559
Email: jzhang@mail.jci.tju.edu
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