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Faculty and Staff Directory

  Esther Biswas, PhD
Assistant Professor
Director, Departmental Research Programs
Program Director, Biotechnology
esther.biswas@jefferson.edu

 


 

Dr. Biswas earned her PhD in Molecular Bioscience from Rutgers/UMDNJ, Piscataway, NJ; her MS degree in Biochemistry from the University of Maryland, Baltimore, MD, and her BS degree from the University of Washington, Seattle, WA.

Her current research interests are in the analysis of the structure and function of biologically important proteins, which involves genetic and biochemical characterization of recombinant proteins generated through in vitro mutagenesis. Projects currently underway are: (i) Molecular analysis of inherited visual diseases, and (ii) Hexameric DNA helicases and control of cell proliferation. These projects are described in detail in the "Molecular Biology Research" section of this web site.

Recent Publications and Activities

  1. Biswas, E. E., P.-H. Chen, & Biswas, S. B. (1995) Biochemical and Genetic Characterization of DNA Helicase B from the Yeast, Saccharomyces cerevisiae. Biochem. Biophys. Res. Comm., 206 850-856.

  2. Biswas, E. E., P.-H. Chen, & Biswas, S. B. (1995) Large Scale Expression, Rapid Purification, and Analysis of Yeast Proliferating Cell Nuclear Antigen (PCNA). Protein Expression and purification, 6, 763-770.

  3. Zhu, F., Biswas, E.E., and Biswas, S. B. (1997) Purification and Characterization of the DNA Polymerase Associated Exonuclease: The RTH1 Gene Product. Biochemistry 43, 5947-5954.

  4. Biswas, E., Zhu, F. X., and Biswas, S. B. (1997) Stimulation of RTH1 Nuclease of the Yeast, Saccharomyces cerevisiae, by Replication Protein A. Biochemistry, 43, 5955-5962.

  5. Biswas, S. B., Chen, P. H. and Biswas, E. E. (1997) Purification and Characterization of DNA Polymerase a Associated & RPA-Dependent Yeast DNA Helicase A. Biochemistry, 43, 13270?13276.

  6. Biswas, E. E., Fricke, W. M., Chen, P. H., and Biswas, S. B. (1997) The Yeast DNA Helicase A: Cloning, Expression, Purification and Enzymatic Characterization. Biochemistry, 43, 13277-13284.

  7. Biswas, E. E. and Biswas, S. B. (1999) Mechanism of DnaB helicase of Escherichia coli: Structural Domains Involved in ATP Hydrolysis, DNA Binding, and Oligomerization. Biochemistry, 38, 10919-10928.

  8. Biswas, E. E. and Biswas, S. B. (1999) Mechanism of DNA Binding by the DnaB helicase of Escherichia coli: Analysis of the Roles of Domain Gamma in DNA Binding. Biochemistry, 38, 10929-10939.

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