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Dr. Biswas earned her PhD in Molecular Bioscience from Rutgers/UMDNJ,
Piscataway, NJ; her MS degree in Biochemistry from the University of Maryland,
Baltimore, MD, and her BS degree from the University of Washington, Seattle,
WA.
Her current research interests are in the analysis of the structure and
function of biologically important proteins, which involves genetic and
biochemical characterization of recombinant proteins generated through
in vitro mutagenesis. Projects currently underway are: (i) Molecular analysis
of inherited visual diseases, and (ii) Hexameric DNA helicases and control
of cell proliferation. These projects are described in detail in the "Molecular
Biology Research" section of this web site.
Recent Publications and Activities
- Biswas, E. E., P.-H. Chen, & Biswas, S. B. (1995) Biochemical
and Genetic Characterization of DNA Helicase B from the Yeast, Saccharomyces
cerevisiae. Biochem. Biophys. Res. Comm., 206 850-856.
- Biswas, E. E., P.-H. Chen, & Biswas, S. B. (1995) Large Scale
Expression, Rapid Purification, and Analysis of Yeast Proliferating
Cell Nuclear Antigen (PCNA). Protein Expression and purification, 6,
763-770.
- Zhu, F., Biswas, E.E., and Biswas, S. B. (1997) Purification and
Characterization of the DNA Polymerase Associated Exonuclease: The RTH1
Gene Product. Biochemistry 43, 5947-5954.
- Biswas, E., Zhu, F. X., and Biswas, S. B. (1997) Stimulation of RTH1
Nuclease of the Yeast, Saccharomyces cerevisiae, by Replication Protein
A. Biochemistry, 43, 5955-5962.
- Biswas, S. B., Chen, P. H. and Biswas, E. E. (1997) Purification
and Characterization of DNA Polymerase a Associated & RPA-Dependent
Yeast DNA Helicase A. Biochemistry, 43, 13270?13276.
- Biswas, E. E., Fricke, W. M., Chen, P. H., and Biswas, S. B. (1997)
The Yeast DNA Helicase A: Cloning, Expression, Purification and Enzymatic
Characterization. Biochemistry, 43, 13277-13284.
- Biswas, E. E. and Biswas, S. B. (1999) Mechanism of DnaB helicase
of Escherichia coli: Structural Domains Involved in ATP Hydrolysis,
DNA Binding, and Oligomerization. Biochemistry, 38, 10919-10928.
- Biswas, E. E. and Biswas, S. B. (1999) Mechanism of DNA Binding by
the DnaB helicase of Escherichia coli: Analysis of the Roles of Domain
Gamma in DNA Binding. Biochemistry, 38, 10929-10939.
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