Rippel Foundation Funds Bone Marrow Transplant Research
For the third time in recent years, the Fannie E. Rippel Foundation
is supporting innovative and vital research at Thomas Jefferson University.
The New Jersey-based Foundation has pledged $176,000 to the Bone Marrow
Transplant Program, directed by Neal Flomenberg, MD, professor of medicine/neoplastic
diseases at Jefferson Medical College. Dr. Flomenberg and his colleagues
are pioneers in the transplantation of bone marrow between patients and
Dr. Flomenberg says, "The Rippel Foundation gift will help ensure that
these transplants are effective for high-risk patients. The gift will fund
construction of a cold room, in which very large quantities of media used
to grow antibodies are stored, and a sterile, clean room, in which contaminants
from the antibody preparation can be safely removed. We will be able to
make state-of-the-art laboratory renovations and purchase additional supplies."
Traditionally, successful transplants have required a "perfect"
or "near-perfect" match in order to avoid graft-versus-host disease
(GVHD), a condition where the grafted marrow rejects the host body into
which it has been placed. Dr. Flomenberg has become one of few physicians
to perform the halpoidentical marrow transplant, a procedure which requires
only a 50 percent similarity between patient and donor.
In addition to this year's donation, the Fannie E. Rippel Foundation has
previously made donations to Jefferson's Bodine Center for Cancer Treatment
and to the Cardiovascular Research Center. The Foundation was incorporated
in 1953 for the purpose of providing funds to assist hospitals, aiding organizations
that provide relief and care of aged women, and assisting those institutions
pursuing treatment and research in the battle against heart disease and