The Jefferson 2000 Fund
Foundation Grants Bolster Research
Three private local foundations have given their support to Jefferson researchers
for scientific investigations that will further the development of new treatments
for cancer and spinal-cord injuries.
A $100,000 gift from the Chichester duPont Foundation will strengthen orthopaedic
research at Jefferson Medical College (JMC).
The gift from the Wilmington, Delaware, foundation supports the research
of Richard A. Balderston, MD, clinical professor of orthopaedic surgery,
JMC, into new technologies to help spinal-cord injury patients.
The gift adds to the campaign advancing the work of the Orthopaedic Research
Laboratory, directed by Richard H. Rothman, MD, PhD, the James Edwards Professor
of Orthopaedic Surgery and department chairman. That campaign has now reached
a total of $4.9 million, about two-thirds of the way to its Phase-I goal
of $7.4 million.
The W. W. Smith Charitable Trust, based in Bryn Mawr, has awarded Jefferson
a one-year, $70,000 grant to fund the work of Scott A. Waldman, MD, PhD.
Dr. Waldman, medical director of the Clinical Research Unit, division of
clinical pharmacology, and associate professor of medicine (pharmacology),
JMC, will continue his research into colorectal cancer treatment with the
W.W. Smith grant.
Dr. Waldman and his team have previously isolated a protein receptor found
only in the intestine. They believe the receptor can target cancer cells
outside the intestine, acting as a "magic bullet" to diagnose
and treat malignancies. With further study, Dr. Waldman hopes to develop
new drug therapies to reduce the grim statistics for colorectal cancer,
the second leading cause of cancer-related deaths in the United States.
Derrick S. Grant, PhD., an investigator at the Cardeza Foundation for Hematological
Research in the department of medicine and assistant professor of medicine,
JMC, is the recipient of a $30,000 grant from the Margaret Q. Landenberger
The one-year Landenberger award funds Dr. Grant's research into the interdependency
of tumor growth and the vascular system. Working closely with colleagues
at the Jefferson Cancer Center, he aims to develop therapies to regulate
the growth of tumor cells more effectively and with fewer side effects.