Urinary Sphincter Prosthesis May Replace Sphincterotomy in Spinal Cord-Injured
Researchers from Thomas Jefferson University Hospital have recently
completed a five-year study of an intraurethral stent prosthesis. This FDA-approved
device has shown potential as a new treatment alternative for spinal cord-injured
men with detrusor-external sphincter dyssynergia (DESD).
DESD is a disturbance of the normal relationship between bladder contraction
and sphincter relaxation during voluntary or involuntary urination. The
stent eliminates the recurrence of urethral strictures, allowing for catheterization
"The intraurethral stent is one of the most promising breakthroughs
for men with this type of bladder dysfunction," explains Michael B.
Chancellor, MD, Assistant Professor of Urology at Jefferson Medical College
and Director of Neuro-urology at Thomas Jefferson University Hospital. "We
are encouraged by the positive results we have received and view the new
procedure as an effective, low-risk treatment for DESD."
Jefferson is one of a few centers on the East Coast using this promising
Each year there are nearly 10,000 new, spinal cord-injured patients in the
United States, 82 percent of whom are men. Many of the patients with complete
spinal cord injury have resulting bladder dysfunction with DESD.