233 S. Tenth Street
Suite 815
Philadelphia, PA 19107
(215) 503-9270
(215) 503-9142 fax
Most Recent Peer-reviewed Publications
- Proteomic profiling of infiltrating ductal carcinoma reveals increased cellular interactions with tissue microenvironment
- Low abundance protein enrichment for discovery of candidate plasma protein biomarkers for early detection of breast cancer
- An integrated framework to model cellular phenotype as a component of biochemical networks
- Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation
- Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classification
Education
PhD, Biomedical Engineering, Drexel University, Philadelphia, PA - 2008
MS, Biomedical Engineering, Drexel University, Philadelphia, PA - 2008
BSE, Biomedical Engineering, Duke University - 2004
Post Doctoral Fellowship
Cancer Biology, Thomas Jefferson University, Philadelphia, PA - 2008-11
University Appointment
2012- Present, Research Instructor
2008-12, Post-doctoral Research Fellow
Expertise & Research Interests
My research is driven by two aims: to identify biomarkers of disease onset and progression and to investigate and describe molecular mechanisms of tumorigenesis and drug action. My expertise is in computational biology and bioinformatics. I have extensive training in tasks necessary for analysis of microarray and proteomic data including normalization, missing value estimation, machine learning, biomarker identification, pathway, gene set and network analysis, visualization and computational modeling. I am also gaining experience in the analysis of next-generation sequence data for investigation of sequence alterations (SNP, indels), copy number variation, transcriptome and exome expression analysis and chromatin immunoprecipitation sequencing.