Kimmel Cancer Center
233 S. Tenth Street
Suite 506
Philadelphia, PA 19107
(215) 503-3443
233 S. Tenth Street
Suite 506
Philadelphia, PA 19107
(215) 503-3443
Most Recent Peer-reviewed Publications
- β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
- PSA regulates androgen receptor expression in prostate cancer cells
- Insulin-like growth factor 1 stimulation of androgen receptor activity requires β 1A integrins
- Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells
- Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer
Education
PhD, Experimental Medicine and Biotechnology, PGIMER, India
Expertise & Research Interests
I am studying the crosstalk between Insulin-like growth factor receptor 1 (IGF-IR) and beta 1 integrins in the regulation of prostate cancer.
Current Research Projects
- Regulation of beta 1 integrins by IGF-IR in Prostate Cancer.
- Role of beta 1 integrins in radiation resistance in TRAMP model of Prostate Cancer.
- Regulation of JNK pathway by IGF-IR and its effect on radiation resistance in Prostate cancer
Keywords
Prostate cancer progression