1015 Walnut Street
Suite 501, Curtis Bldg.
Philadelphia, PA 19107
Suite 501, Curtis Bldg.
Philadelphia, PA 19107
Most Recent Peer-reviewed Publications
- Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity
- Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues
- Tumor necrosis factor α- And interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
- The expression and relationship of pro-inflammatory chemokine RANTES/CCL5 and Cytokine IL-1β in painful human intervertebral discs
- Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
- Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling
- Smad3 controls β-1,3-glucuronosyltransferase 1 expression in rat nucleus pulposus cells: Implications of dysregulated expression in disc disease
- Expression of Prolyl Hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: Distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia
- Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: Role of Hsp70 in HIF-1α degradation
- Is the spinal motion segment a diarthrodial polyaxial joint: What a nice nucleus like you doing in a joint like this?
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- HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
- TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc
- An organ culture system to model early degenerative changes of the intervertebral disc
- Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc
- Notochordal cells in the adult intervertebral disc: New perspective on an old question
- Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: Role of hypoxia-inducible factor proteins
- Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease
- Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression
- Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: Possible implications in controlling dystrophic mineralization in the intervertebral disc