05B4 Iozzo, Renato V. - Jefferson Medical College - Thomas Jefferson University
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Renato V. Iozzo, MD

Contact Dr. Iozzo

1020 Locust Street
Jefferson Alumni Hall, Suite 249
Philadelphia, PA 19107

(215) 503-2208
(215) 923-7969 fax

Most Recent Peer-reviewed Publications

  1. Heparanase: Multiple functions in inflammation, diabetes and atherosclerosis
  2. Decorin potentiates interferon-γ activity in a model of allergic inflammation
  3. Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells
  4. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis
  5. Biological interplay between proteoglycans and their innate immune receptors in inflammation
  6. Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1
  7. Dichotomy of decorin activity on the insulin-like growth factor-I system
  8. Mast cells produce novel shorter forms of perlecan that contain functional endorepellin a role in angiogenesis and wound healing
  9. Decorin expression is important for age-r 1281 elated changes in tendon structure and mechanical properties
  10. Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: Transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factor of activated T cell 1 (NFAT1) activation
  11. The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis
  12. The biology of small leucine-rich proteoglycans in bone pathophysiology
  13. Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model
  14. Decorin: A guardian from the matrix
  15. Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells
  16. Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation
  17. Targeting heparanase for cancer therapy at the tumor-matrix interface
  18. Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon
  19. Thrombospondins in physiology and disease: New tricks for old dogs
  20. Decorin-TGFβ Axis in Hepatic Fibrosis and Cirrhosis
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