Division of Population Science
Markers, Models & Mechanisms
As of January 2011, the Division’s funded research included the following:
MicroRNA Genetic Variations as Predictors of Hepatocellular Carcinoma Risk
Goal: Evaluate the effect of a pilot panel of microRNA-related genetic variations on the risk of developing hepatocellular carcinoma in patients with chronic hepatitis B infection.
Pennsylvania Department of Health funded study
(01/01/10-12/31/11)
Principal Investigator: Hushan Yang
Genetic Variations in Inflammation Pathway as Novel Predictive Markers for Risk of Hepatocellular Carcinoma: a Pilot Study
Goal: Evaluate a pilot panel of genetic variations in the inflammation pathway genes and risk of HBV-related HCC.
American Cancer Society-funded Institutional Research Grant
(07/01/10-06/30/11)
Principal Investigator: Hushan Yang
Inflammation Variants and Risk of Hepatocellular Carcinoma in HBV Patients
Goal: Assess the implication of a comprehensive panel of inflammation-related polymorphisms in HBV-HCC risk.
NIH/NCI-funded study
(07/01/2010-06/20/2012)
Principal Investigator: Hushan Yang
Predisposition to Hepatocellular Carcinoma in HBV patients –
A Multigenic Approach to MicroRNA
Goal: A muti-disciplinary approach to comprehensively evaluate the involvement of microRNAs in the development of HBV-HCC.
V Foundation for Cancer Research
(12/01/2010-11/30/2012)
Principal Investigator: Hushan Yang

