Susan Littman, MD

Contact Dr. Littman

925 Chestnut Street
Suite 320A
Philadelphia, PA 19107

(215) 955-8874

Medical School
Albany Medical College - 1989

Residency
University of Texas SW Medical School, Dallas

Fellowship
Duke University Medical Center

Board Certification

Hospital Appointment
Thomas Jefferson University Hospital
Methodist Hospital Division of Thomas Jefferson University Hospital

Hospital Appointment
Active Medical Staff

University Appointment
Assistant Professor of Medical Oncology

Research and Clinical Interests
Medical Oncology, Gastronintestinal Cancer, Colorectal Cancer, Liver Cancer, Pancreatic Cancer, Esophageal Cancer, Stomach Cancer

Publications

Most recent Peer-reviewed Publications

1. The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase
2. Etiology of the mutational spectrum of ras genes in human carcinomas
3. Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability
4. Repair of large insertion/deletion heterologies in human nuclear extracts is directed by a 5' single-strand break and is independent of the mismatch repair system
5. Erratum: Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα (Journal of Biological Chemistry (1998) 273 (19895-19901))
6. Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
7. Increased transversions in a novel mutator colon cancer cell line
8. A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype
9. Binding of unglycosylated and glycosylated human recombinant interferon-γ to cellular receptors
10. Binding of human recombinant 125I -interferon γ to receptors on human cells