Center for Translational Medicine
Facilities
Our Center’s core research facilities are currently supporting research projects from within the Center, collaborative research with other Jefferson departments such as Emergency Medicine and The Kimmel Cancer Center. In addition, our cores have supported other academic institutions and industries.
Animal Models of Human Disease & Cardiac Physiology Core
This Core provides support for animal studies involving cardiac diseases and measuring in vivo cardiac physiology. We have developed and standardized many small animal surgical models and measuring instruments suitable for translational research.
The Viral Vector Core
This Core provides support for gene therapy studies in small and large animals involving cardiac diseases. Our on-going research is continuing to increase the transduction efficiency of our delivery vehicles derived from the human parvovirus Adeno-associated virus (AAV).
In the News
082911 — New Gene Therapy to Reverse Heart Failure Ready for Clinical Trials
122908 — Gene Therapy Reversed Heart Damage in Heart Failure
081908 — Molecule Found to “Turn On” Genes that lead to Heart Failure, Jefferson Scientists Show
031808 — Signaling Protein Helps Limit Damage in Heart Attack, Jefferson Scientists Show

