Kurt Chuprun, Ph.D.

Contact Dr. Chuprun

Center for Translational Medicine
1025 Walnut Street, Suite 302 Philadelphia, PA 19107

(215) 503-5610
(215) 503-5728 fax

Degree
Ph.D. University of Cincinnati College of Medicine, 1992

Research and Clinical Interests
Novel Modes of Regulation of the G-protein Coupled Receptor Kinase Family

Publications

Most Recent Peer-reviewed Publications

1. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
2. Endothelial S100A1 modulates vascular function via nitric oxide
3. Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress
4. Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart
5. Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue
6. S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction