Center for Translational Medicine
Research at the Center
Eugene Feiner Laboratory for Vascular Biology & Thrombosis
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George Zallie & Family Laboratory for Cardiovascular Gene Therapy
From Research to the Power to Cure
The Center for Translational Medicine at Jefferson is primarily focused on bridging cutting-edge basic research with clinical medicine in order to more efficiently translate new discoveries at the bench to the realization of improved patient care.
Our Center, which is at the forefront of academic medicine, creates a new culture of collaboration and cooperation, merging a world-class team of basic science investigators with Jefferson’s renowned physicians and clinical investigators.
Research
The research activities of the Center for Translational Medicine are broad and multi-focal. As the number-one killer of both men and women in the U.S., our Center has particular interest and expertise in the area of cardiovascular diseases.
Center laboratories study the regulation and signaling of many molecules vital in the progression in heart muscle diseases utilizing novel genetically engineered mouse models or viral-mediated myocardial gene delivery. Targets include Cellular Receptors, Kinases and Cell Adhesion Proteins (Koch, Feldman, Force, Most, Radice and Chan).
We are also leading investigation in the mechanism of potentially fatal cardiac toxicities detected in many cancer-fighting drugs and part of a multi-center registry for patients receiving potentially Cardiotoxic Anti-cancer Drugs.
Other center laboratories focus on diseases in the vasculature (Eckhart and Peppel), Platelets and Genetic Analysis and linage to diseases of the cartilage and bone.
Finally, our center also leading research in Viral Vector development and Small Animal Surgery.
