Department of Radiology
Nuclear Medicine/ Molecular Imaging Division
Background | Staff | Services Offered | Research | Training |
Myocardial perfusion study demonstrating a large fixed defect involving the inferolateral left ventricular wallCardiothoracic Imaging
Cardiothoracic nuclear medicine procedures include stress myocardial perfusion imaging, utilizing state-of-the-art gamma cameras used exclusively for imaging of the heart, as well as gated blood pool imaging for the evaluation of ventricular contractility. Lung ventilation/perfusion imaging is utilized for the diagnosis of pulmonary thrombo-embolic disease.
More Images: Image 1Multi-gated analysis of cardiac function for evaluation of side effects of cardiotoxic chemotherapeutic agents Image 2Ventilation/perfusion scan demonstrating multiple perfusion defects, consistent with high probability of pulmonary emboli
Hepatobiliary scan demonstrating persistent non-visualization of the gallbladder, indicative of cholecystitisRadionuclide Gastrointestinal Procedures
The division performs all radionuclide gastrointestinal tract procedures, notably hepatobiliary imaging (HIDA) for the evaluation of cholecystitis, biliary obstruction, bile leaks, as well as gallbladder contractility evaluation. GI bleeding detection studies are also performed, as well as tomographic liver (SPECT) imaging for evaluation of liver masses. Salivary gland imaging is also offered.
More Images: Image 1Gastric emptying study of a patient with abdominal pain and nausea, demonstrating markedly delayed gastric emptying Image 2Gastrointestinal bleeding scan demonstrating a focus of active colonic bleeding at the hepatic flexure
Renal scan, demonstrating acute tubular necrosis of the transplanted kidney
Renal Nuclear Medicine Procedures
Radionuclide evaluation of kidney disorders include renal function assessment (split function), lasix washout analysis and renal transplant evaluation.
Whole-body bone scan, demonstrating numerous osseous metastases from prostate cancer
Benign and malignant bone diseases are studied in the division. These include whole body bone imaging for the assessment of bony metastases, so-called three-phase bone scans for sports medicine (fracture evaluation), and other benign disorders such as bone infection, metabolic bone diseases, and reflex sympathetic dystrophy. Another tool utilized for bone infection, or infection involving any organ system, is the use of radiolabeled white blood cell scans. Bone mineral density measurements are performed utilizing a dual energy x-ray absorptiometry (DEXA) scanner.
Thyroid scan, demonstrating Graves diseaseNuclear Endocrine Procedures
The Nuclear Medicine Division at Jefferson is a major referral center for most endocrine disorders, benign and malignant. These include thyroid imaging, thyroid cancer whole body surveillance imaging, parathyroid scanning, adrenal imaging (I-123 MIBG), and somatostatin receptor tumor imaging, i.e. Octreoscan. Radioiodine therapy is performed for the treatment of both hyperthyroidism and thyroid cancer.
More Images: Image 1Iodine-131 whole body scan demonstrating metastasis to cervical lymph node and residual thyroid bed uptake in patient with papillary thyroid cancer Image 2Parathyroid scan, demonstrating left inferior parathyroid adenoma
PET/CT scan of patient with breast cancer demonstrating diffuse metastatic disease
PET/CT Oncologic Imaging
The most commonly performed examination for the oncology patient is positron emission tomography (PET), an imaging study that uses radiolabeled glucose metabolism in malignant cells for the diagnosis, staging, and re-staging of tumors, and for monitoring of therapy. The division uses a state-of-the-art PET scanner that is combined with a CT scanner i.e. PET/CT. Other oncologic procedures include sentinel lymph node mapping in patients with breast cancer and melanoma, neuroendocrine tumor imaging with Octreoscan and radiolabeled monoclonal antibodies for the treatment of chemotherapy-refractory Non-Hodgkin’s lymphoma.
Central Nervous System Imaging
Neurologic nuclear imaging procedures include tomographic brain blood flow imaging (SPECT), metabolic brain evaluation in dementia and seizure disorders utilizing PET/CT, as well as cerebral spinal imaging for cerebral spinal fluid leakage and brain shunt evaluation.