MD/PhD Program
Program Faculty
Clicking on the faculty member's name will take you thier Faculty Interests Profile page for more information regarding thier area of research.
 | David Abraham, Ph.D. Immunity to parasitic infections |  | Emad S. Alnemri, Ph.D. Molecular mechanisms of apoptosis; Role of inflammation in cancer |
 | Andrew E. Aplin, Ph.D. Mutant B-RAF and integrin signaling in melanoma |
 | Jeffrey L. Benovic, Ph.D. Dysregulation of G protein signaling in cancer |
 | Bruno Calabretta, M.D., Ph.D. Mechanisms of leukemogenesis by oncogenic tyrosine kinases |
 | Gino Cingolani, Ph.D. Nucleocytoplasmic transport; Virus assembly; Multisubunit ATPases; Structural and biophysical techniques |
 | Manuel L. Covarrubias, M.D., Ph.D. Function, structure and pharmacology of voltage-gated ion channels in excitable tissues |
 | Laurence C. Eisenlohr, V.M.D., Ph.D. Antigen processing and presentation; Anti-viral responses; Vaccine development; tolerance and autoimmunity; Cancer immunotherapy |
 | Andrzej Fertala, Ph.D. Heritable diseases of connective tissues. |
 | Thomas L. Force, M.D. Cardiotoxicity of targeted cancer therapeutics; Signaling mechanisms driving cardiac hypertrophy and ischemic injury |
 | Mark E. Fortini, Ph.D. Notch receptor signaling in tissue formation; Biochemical and cell biological events regulating Notch activation |
 | Linda Greenbaum, M.D. Transcriptional control of hepatocyte proliferation; Signaling pathways in hepatic progenitor cells regulating liver repair and carcinogenesis |
 | Noreen J. Hickok, Ph.D. Bone-bacterial-biomaterial interface; Mechanisms of bacterial colonization and biofilm formation; Therapies to interrupt bacterial adhesion and host tissue colonization |
 | Jan B. Hoek, Ph.D. Effects of ethanol on integrated signaling responses in liver; Cell signaling and mitochondrial function; Signaling associated with liver homeostasis, stress responses, and regeneration |
 | D. Craig Hooper, Ph.D. Neuroimmunology and viral infections |
 | Lorraine Iacovitti, Ph.D. Stem cells to study and treat Parkinson's disease; Neuroprotective agents to treat Parkinson's Disease; Stem cells to treat stroke; Sites of adult stem cells in brain |
 | Renato V. Iozzo, M.D. Proteoglycan control of cancer growth and angiogenesis; Tumor microenvironment and regulation of receptor tyrosine kinases by matrix molecules |
 | Erik S. Knudsen, Ph.D. Signaling through the RB-pathway controlling physiology and therapeutic response; Role of RB in stress response and liver disease |
 | Karen E. Knudsen, Ph.D. Hormone signaling in the male reproductive tract; Impact of androgen receptor function on prostate development and disease |
 | Michael P. Lisanti, M.D., PhD. Functional role of caveolae in signal transduction and human disease |
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My G. Mahoney, Ph.D. Role of desmosomal proteins in cell adhesion, signaling, morphogenesis, and skin cancer development |
 | Tim Manser, Ph.D. Antigen-dependent stages of B cell differentiation leading to the generation of B cell memory |
 | Alexander Mazo, Ph.D. Epigenetic function of Drosophila ortholog of the MLL oncogene |
 | James P. McGettigan, Ph.D. Investigating vaccine-induced T and B cell responses against viral infections |
 | Steven B. McMahon, Ph.D. Deregulation of the p53 and MYC transcription networks driving cancer |
 | A. Sue Menko, Ph.D. Signaling mediating acquisition of the differentiated cell phenotype; Cell adhesion and the cytoskeleton in regulating tissue morphogenesis, regeneration, and fibrosis |
 | Diane E. Merry, Ph.D. Molecular determinants of androgen receptor metabolism and of polyglutamine-expanded androgen receptor misfolding and aggregation |
 | Michael O'Leary, Ph.D. Molecular mechanisms of sensory transduction in the peripheral nervous system |
 | Michael Oshinsky, Ph.D. Recurrent episodic headache syndromes |
 | John M. Pascal, Ph.D. Structural biology and biochemistry of the DNA damage response and mechanisms for maintaining genetic integrity |
 | Fabienne M. Paumet, Ph.D. Role of phagocytosis in the pathogenesis of infectious diseases; Role of phagocytosis in mast cell function in allergy |
 | Richard G. Pestell, M.D., Ph.D. Cell cycle control in cancer. |
 | Natalia A. Riobo, Ph.D. Role and mechanisms of Hedgehog signaling in proliferation, survival and cell migration |
 | Makarand V. Risbud, Ph.D. Intervertebral disc biology; Hypoxic tissue niches; Stem cell biology; Tissue engineering and regenerative medicine |
 | Michael J. Root, M.D., Ph.D. Mechanisms of viral and cell-cell membrane fusion; HIV entry inhibitor design and vaccine development; Osteoclast formation/macrophage fusion. |
 | Abdolmohamad Rostami, M.D., Ph.D. Helper T cell subsets and their cytokines in the pathogenesis of autoimmune encephalomyelitis (EAE) and multiple sclerosis; Effect of the Bowman-Birk serine protease inhibitor on the course of EAE; Mechanisms of intravenous tolerance in EAE; Effects of interleukin-27 (IL-27) on human auto-aggressive T cells |
 | Hallgeir Rui, M.D., Ph.D. Molecular biology and signaling by receptors for lactogenic hormones; Endocrine regulation of breast cancer |
| Jay S. Schneider, Ph.D. Parkinson's disease; Heavy metal neurotoxicity |
 | Matthias J. Schnell, Ph.D. Development of novel vaccines and viral pathogenesis |
 | Irving M. Shapiro, Ph.D. Chondrocyte apoptosis and autophagy; Stem cell function in the intervertebral disc; Development of methods to attach bioactive substances to metals utilized for orthopaedic implants |
 | Linda D. Siracusa, Ph.D. Genetics of cancer susceptibility |
 | Yuri K. Sykulev, M.D., Ph.D. Molecular mechanisms regulating cytotoxic T lymphocyte activity |
 | Theodore F. Taraschi, Ph.D. Role of defective DNA mismatch repair in the development of antimalarial drug resistance |
 | Davide Trotti, Ph.D. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis |
 | Jouni Uitto, M.D., Ph.D. Biology of connective tissue related to cutaneous diseases that increase the risk of aggressive squamous cell carcinomas |
 | Elisabeth J. Van Bockstaele, Ph.D. Cannabinoid modulation of noradrenergic circuits; Stress and vulnerability to psychiatric disorders; Opioid receptor signaling and interacting proteins; Mechanisms of synaptic plasticity; Neurotransmitter release and receptor dynamics |
 | Scott A. Waldman, M.D., Ph.D. Tumor suppressors and their signaling pathways in GI malignancies; Targeted diagnostics and therapeutics in cancer |
 | Philip B. Wedegaertner, Ph.D. Heterotrimeric G protein regulation of intracellular trafficking; Role of RhoGEFs in mitosis |
 | Eric Wickstrom, Ph.D. Genetic diagnosis of cancer by imaging activated mRNAs in tumors; Analysis of circulating tumor cells; Genetic therapy of cancer by knockdown of activated genes and miRNAs |
 | Edward Winter, Ph.D. Molecular/genetic analyses of signaling and transcriptional regulation using meiotic development in S. cerevisiae as a model |
