Basic Research Studies > Corticotropin-Releasing Factor (CRF)-serotonin (5-HT) interactions

Corticotropin-Releasing Factor (CRF)-serotonin (5-HT) interactions

	Rita Valentino, PhD Children's Hospital of Philadelphia Principal Investigator (NIH/NIDA)	CRF and vGlut1 in the dorsolateral DRN
	Elisabeth J. Van Bockstaele, PhD Co-Investigator
	Maria Waselus Graduate Student Molecular Cell Biology Program

Goal: To examine interactions between the stress hormone CRF and serotonin (5-HT) in the dorsal raphe nucleus (DRN). Ultrastructural studies examining CRF afferents and their post-synaptic targets in DRN subregions are intended to elucidate the anatomical substrates involved in the regulation of the DRN-5-HT system by CRF.