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Office of Technology Transfer
and Business Development
1020 Locust Street, Suite M34
Philadelphia, PA 19107
(215) 955-6862
Contact us through e-mail

Specific List For "Drug Discovery"

Case Number

Title

Non-Confidential Summary

Issued Patent

Lead Inventor's Website

AKS_EDI.001

Modification of Western Blotting Procedure to Generate a Higher Quantitative Data Output with Reduced Errors

NCS for AKS_EDI.001

       

 

ALN_EMA.023

The ASC Supramolecular Assembly Complex (ASC SMAC), Compositions for Making and Using the Same

NCS for ALN_EMA.023

       

Link

BAS_REN.005

Cell Lines which Constitutively Express IGF-1 and IGF-1 R

 

[US Patent No. 5,262,308]
     

Link

BEN_JEF.003

Compositions And Methods For Modulating The Activity Of G Protein-Kinases

 

[US Patent No. 6,255,069]
     

Link

BER_ERI.002

An In Vivo And In Vitro Model Of Cutaneous Photoaging

 

[US Patent No. 5,648,061]
[US Patent No. 6,018,098]
   

Link

BLO_TIM.002

Glucosidase Inhibitors as a Treatment for Viruses that Bud from the Endoplasmic Reticulum

 

       

 

BLO_TIM.014

A Serum Protein Marker for Diagnosing Liver Trauma and Hepatocellular Carcinoma

NCS for BLO_TIM.014 & FEI_MAR.003

       

 

BRO_JON.001

The Specific Level of Expression and Localization of a Key Signaling Protein Can Dictate And Predict The Response Of The Most Commonly Used Chemotherapeutic Used In The Treatment Against Pancreatic Cancer, Ovarian Cancer And Metastatic Breast Cancer

NCS for BRO_JON.001

       

Link

CHU_MON.001

Fibulin-2 Null Mutant Mice

 

       

Link

CRO_CAR.002

Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

       

 

CRO_CAR.004

The Human FHIT Gene

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

[United States Patent: 7220834]
[United States Patent: 6774217]
[United States Patent: 6242212]
[United States Patent: 5928884]

 

CRO_CAR.009

TCL-1 Gene And Protein And Related Methods And Compositions

NCS for Croce TCL-1 techs (CRO 9,15)

       

 

CRO_CAR.015

Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression

NCS for Croce TCL-1 techs (CRO 9,15)

       

 

CRO_CAR.016

Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

       

 

CRO_CAR.017

Role of microRNA Genes In Human Cancer

NCS for Croce miRNA techs (CRO 17, 25)

       

 

CRO_CAR.019

Involvement Of The ALL-1 Gene In A Solid Tumor1

 

[US Patent No. 5,567,586]
     

 

CRO_CAR.025

microRNA genes in cancer diagnosis and treatment

NCS for Croce miRNA techs (CRO 17, 25)

       

 

DAN_REN.003

Targeting of Integration of Retroviral Vectors by Manipulation Integration Cofactors

NCS for DAN_REN.003

       

Link

DAN_REN.005

Methods to Measure Frequency of Integration in the Vicinity of Active Genes

 

       

Link

FEI_MAR.001

A Transgenic SCID Mouse Model For Hepatitis B Virus Replication And Associated Liver Disease

 

[US Patent No. 6,087,556]
     

 

FEL_ART.001

Adenosine A1 Receptor Mutations Predict Infarct Size

NCS for FEL_ART 001, 003

       

Link

FEL_ART.003

Use of Adenosine Receptor Subtypes as Therapeutic Targets

NCS for FEL_ART 001, 003

       

Link

HUA_ZIW.001

Small Molecules Inhibitor of BCL-2

HUA_ZIW.001, .006, .011 NCS

[US Patent No. 6,492,389]
     

 

HUA_ZIW.006

Enhancement of Peptide Cellular Uptake

HUA_ZIW.001, .006, .011 NCS

[US Patent No. 6,713,280]
     

 

HUA_ZIW.011

Synthesis of 4-H Chromene Derivatives Compounds that Bind Bcl-2 Protein and Induce Apoptosis in Tumor Cells

HUA_ZIW.001, .006, .011 NCS

[US Patent No. 6,660,871]
     

 

IAC_LOR.001

A Human Model System For In Vitro Development Of The Dopaminergic Phenotype

NCS for IAC_LOR.001

[US Patent No. 7,195,910]
     

Link

IOZ_REN.001

A Role For Decorin In Tumor Suppression

 

[US Patent No. 6,524,573]
     

Link

IOZ_REN.009

Endorepellin, A Novel Inhibitor of Angiogenesis Derived from the Carboxyl Terminus of Perlecan

NCS for IOZ_REN.009

[US Patent No. 6,821,947]
     

Link

KHI_JAS.001

Humanized Cartilage in Mouse

 

[US Patent No. 6,448,470]
     

 

KMI_ERI.002

Mammalian and Human REC2

 

[US Patent No. 6,410,226]
     

 

KMI_ERI.004

Chimeric Mutation Vectors Having Non-Natural Nucleotides

 

[US Patent No. 5,731,181]
[US Patent No. 5,795,972]
   

 

KMI_ERI.005

Methods for Enhancing Gene Conversion or Genetic Repair by Chimeric Oligonucleotides

 

       

 

KMI_ERI.007

Compositions and Methods to Promote Homologous Recombination in Eukaryotic Cells and Organisms

 

[US Patent No. 5,780,296]
     

 

KMI_ERI.008

Compounds and Methods for Site-Directed Mutations in Eukaryotic Cells

 

[US Patent No. 5,756,325]
     

 

KOC_WAL.001

GRK2 Activity as a Therapeutic Target for Heart Failure

NCS for KOC_WAL.001

       

Link

KOP_HIL.006

Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins

 

[US Patent No. 6,042,832]
[US Patent No. 6,448,070]
   

Link

KOP_HIL.021

Generation of Plant-Based Recombinant Subunit Vaccine Against Smallpox

NCS for KOP_HIL.021

       

Link

NEV_MAR.001

Establishment of a New Human Androgen-Dependent Prostate Cancer Cell Line that is Tumorigenic in Nude Mice

NCS for NEV_MAR.001

       

Link

OSH_MIC.001

Chronic Recurring Migraine Headache Model in Rodents

 

       

Link

RAB_JOS.001

Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression

NCS for RAB_JOS.001

       

Link

SAN_JAM.003

Novel Method to Rapidly Promote Angiogenesis

NCS for SAN_JAM.003

       

Link

SHA_KUM.013

Treatment of kidney disease with the Hormone Adiponectin

NCS for SHA_KUM.013

       

 

SIM_LAN.004

A Vaccine Against Botulinum that Does Not Bind to the Nervous System

NCS for SIM_LAN.004

       

Link

SIR_LIN.001

Fibrillin 1 Gene Comprising Suplication Mutation and Method of and Compositions and Kits for Detecting and Using the Same

 

[US Patent No. 6,010,694]
     

Link

SYK_YUR.004

Invention of a Novel Serum Free Media for Cultivation of Hybridoma Cells to Achieve Production of Highly Homogenous Monoclonal Antibodies (MAb) in Preparative Scale

 

       

Link

THO_JEF.001

Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal

 

[US Patent No. 6,358,536]
     

 

TSI_PHI.002

Inhibition of TPL2 to Treat Inflammatory Diseases

 

[US Patent No. 6,660,906]
     

 

WIC_ERI.002

Peptide Nucleic Acid Conjugates

 

[US Patent No. 6,180,767]
     

Link

WIL_KEV.001

Human Genomic Clone Encoding Human Chondroitin 6-Sulfotransferase

 

[US Patent No. 6,399,358]
     

 

WON_ALB.005

The Rapid Identification of Alternative Splicing (RIAS) Method

 

       

 

 

 

For further information, please contact Lisa Lau (lisa.lau@jefferson.edu) or Debbie Wang (debbie.wang@jefferson.edu) at 215-955-6862.

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