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Anni, Ph.D., Eleni
Research Assistant Professor Phone: (215) 955-5110 Email: eleni.anni@jefferson.edu
University of Patras, Greece, 1984. Biomarkers of alcoholism, anti-alcoholism drugs and proteomics.
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Behling, Eric
Assistant Professor
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Bibbo, Marluce
Professor Phone: (215) 955-1197 Email: marluce.bibbo@mail.tju.edu
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Bichenkov, Eugeney E
Research Assistant Professor Email: Eugeney.Bichenkov@jefferson.edu
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Birk, Ph.D., David E.
Professor Phone: (215) 503-7855 Email: David.Birk@jefferson.edu
Wayne State, 1981. Developmental biology of extracellular matrix assembly in tendons and the cornea; mechanisms regulating collagen fibrillogenesis and tissue-specific fibril formation.
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Cahill, Ph.D., Alan
Associate Professor Phone: (215) 955-0630 Email: Alan.Cahill@jefferson.edu
London, 1992. Mitochondrial dysfunction and alcoholic liver disease (ALD); relationship between ethanol-derived free radical production and hepatic mitochondrial DNA damage; protection by dietary supplements; role of aging in progression of ALD.
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Covarrubias, M.D., Ph.D., Manuel L.
Professor Phone: (215) 503-4341 Email: Manuel.Covarrubias@jefferson.edu
The structure, function and regulation of voltage-gated potassium channels
The long-term goal of our research is to gain mechanistic insights into the
molecular basis of electrical signaling in neuronal and cardiac tissues. To
reach this goal, we investigate two separate aspects: 1) the molecular
physiology of somatodendritic potassium channels, and 2) the molecular
architecture of a general anesthetic site in potassium channels.
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Csordas, Gyorgy
Research Assistant Professor Email: Gyorgy.Csordas@jefferson.edu
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Cunnane, Mary F
Associate Professor Email: Mary.Cunnane@jefferson.edu
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Curtis, Mark T.
Professor Phone: (215) 955-5110 Email: Mark.Curtis@jefferson.edu
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Edmonston, Tina
Assistant Professor Phone: 215-955-6373 Email: Tina.Edmonston@mail.tju.edu
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Eisenman, Ph.D., Leonard M.
Professor Phone: (215) 503-1686 Email: Leonard.Eisenman@jefferson.edu
Duke, 1974. Neuroscience: anatomical, developmental, and functional studies of the organization of the cerebellum with the use of rodents and neurologically mutant mice, with an emphasis on development of the topographic and synaptic organization of afferent systems to the cerebellum.
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Ellingson, Ph.D., John S.
Associate Professor Phone: (215) 503-5021 Email: John.Ellingson@jefferson.edu
Michigan, 1967. To gain information relevant for correcting myelin-associated pathologies, e.g., multiple sclerosis or fetal alcohol syndrome, we are investigating the molecular and cellular regulation of myelin formation in differentiating oligodendrocytes, with an emphasis on identifying 1) the roles of protein kinase C (PKC) isozymes and 2) the ethanol-affected regulatory systems.
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Farber, M.D., John L.
Professor Phone: (215) 503-5066 Email: John.Farber@jefferson.edu
Professor; M.D., University of California (San Francisco), 1966. Biochemical mechanisms of cell injury in ischemia of liver cell necrosis; biochemical toxicology of activated oxygen; chemical carcinogenesis.
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Fenderson, Ph.D., Bruce A.
Associate Professor Phone: 215-503-2256 Email: Bruce.Fenderson@jefferson.edu
Johns Hopkins, 1980. Mechanisms of morphogenesis and malignancy; role of cell-surface carbohydrates in mediation of cell recognition during development; use of monoclonal anticarbohydrate antibodies to study lineage formation, cell differentiation, and neoplastic transformation.
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Gonye, Ph.D., Gregory E.
Research Assistant Professor Phone: (215) 955-0580 Email: ggonye@mail.dbi.tju.edu
Connecticut, 1993. Molecular neuroscience: role of transcriptional regulation in neuromodulation, concentrating on nucleus tractus solitarius neurons, neuropeptides (angiotensin II), and RGS proteins; effects of ethanol on neuromodulation; development of computational approaches to study neuromodulation, including modeling and simulation and bioinformatic tools.
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Grunwald, Ph.D., Gerald B.
Professor & Associate Dean Phone: (215) 503-4191 Email: Gerald.Grunwald@jefferson.edu
Professor; Ph.D., Wisconsin, 1981. Developmental biology and neuroscience; eye development and disease, analysis of the role of cadherin cell adhesion molecules in normal and abnormal embryonic development and in proliferative diseases of the nervous mechanisms of cadherin expression and function.
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Gulati, Gene L.
Professor Phone: (215) 955-2682 Email: Gene.Gulati@jefferson.edu
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Hajnoczky, Ph.D., Gyorgy
Professor Phone: (215) 503-1427 Email: Gyorgy.Hajnoczky@jefferson.edu
Semmelweis, Budapest, 1987; Ph.D., National Academy of Sciences, Hungary, 1995. Intracellular calcium signaling; inositol trisphosphate-linked hormones; organization of calcium mobilization from endoplasmic/sarcoplasmic reticulum; mitochondrial calcium signaling; calcium-dependent control over life and death of cells; fluorometric, fluorescence microscope imaging and electrophysiological approaches.
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Ho, Cojen
Research Assistant Professor Phone: (215) 503-4034 Email: Cojen.Ho@jefferson.edu
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Hoek, Ph.D., Jan B.
Professor & Vice Chair Phone: (215) 503-5016 Email: Jan.Hoek@jefferson.edu
Amsterdam, 1972. Systems biology of intracellular signal transduction networks; deregulation of cytokine and growth factor signaling in the liver associated with chronic alcohol consumption; early signaling responses during liver regeneration; bioenergetics and mitochondrial metabolism and its role in intracellular signaling and apoptosis.
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Iozzo, M.D., Ph.D., Renato V.
Professor & Director, Extracellular Matrix Program Phone: (215) 503-2208 Email: Renato.Iozzo@jefferson.edu
Florence, 1975. Biosynthesis, structure, and metabolism of proteoglycans in normal and malignant cells; analysis of the cell-surface heparin sulfate proteoglycan synthesized by human colon carcinoma cells, and the regulation of molecular assembly, posttranslational modifications, and turnover of this class of macromolecules; interactions between malignant epithelial cells and normal mesenchymal cells in vitro and the effects on extracellular matrix gene expression.
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Joseph, Ph.D., Suresh K.
Professor Phone: (215) 503-1221 Email: Suresh.Joseph@jefferson.edu
Bristol (England). Structure, function, and regulation of the inositol trisphosphate receptor (IP3R); biosynthesis and assembly of IP3R homo- and heteroligomers; mechanisms of proteosomal and lysosomal degradation of IP3R.
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Jungkind, Donald L
Professor Email: Donald.Jungkind@jefferson.edu
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Kaulin, Yuri A
Research Assistant Professor Email: Yuri.Kaulin@jefferson.edu
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Kenyon, Lawrence C.
Associate Professor Phone: (215) 955-2071 Email: Lawrence.Kenyon@jefferson.edu
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Kholodenko, Ph.D., Boris N.
Research Professor Phone: (215) 503-1614 Email: Boris.Kholodenko@jefferson.edu
Moscow, 1976. Systems biology; quantitative analysis of spatio-temporal dynamics of cellular signaling and gene networks through biochemical, molecular biological, genetic, and computational cell biology methods.
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Kiyatkin, Anatoly
Research Assistant Professor Phone: (215) 503-4794 Email: Anatoly.Kiyatkin@jefferson.edu
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Kocher, William D.
Clinical Assistant Professor Phone: (215) 966-6725 Email: William.Kocher@jefferson.edu
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Kuo, Bruce A
Instructor Email: Bruce.Kuo@jefferson.edu
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Lian, Zhaorui
Research Assistant Professor Phone: 215-503-1037 Email: Zhaorui.Lian@jefferson.edu
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Markevitch, Nikolai
Instructor Email: Nikolai.Markevitch@jefferson.edu
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Mc Closkey, Laura
Clinical Assistant Professor Phone: 215-955-1414 Email: Laura.McCloskey@jefferson.edu
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McCue, Peter A.
Professor Phone: (215) 955-5588 Email: Peter.McCue@jefferson.edu
CUNY, Mount Sinai, 1977. Clinical and experimental pathobiology of neoplasia: effects of retinoids on the differentiation of germ cells and related tumors; role of nuclear receptors and cytosolic-binding proteins for retinoic acid in differentiation-defective cell lines.
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Menko, Ph.D., A. Sue
Professor Phone: (215) 503-2166 Email: sue.menko@jefferson.edu
Pennsylvania, 1978. Role of integrins in the regulation of cell differentiation: Integrin signalling of cell differentiation events, particularly integrin-growth factor receptor coordinated signalling.
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O'Hara, Brian J.
Associate Professor Phone: 215-955-4404 Email: brian.ohara@jefferson.edu
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O'Leary, Michael E.
Research Assistant Professor Phone: (215) 503-9983 Email: Michael.O'Leary@mail.tju.edu
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Palazzo, Juan P.
Professor Phone: (215) 955-6352 Email: Juan.Palazzo@jefferson.edu
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Philp, Ph.D., Nancy J.
Associate Professor Phone: 215-503-7854 Email: Nancy.Philp@jefferson.edu
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Ponnappa, Ph.D., Biddanda C.
Associate Professor Phone: (215) 503-5018 Email: biddanda.ponnappa@jefferson.edu
Current research interests include a) development of liposome-mediated drug delivery system to target macrophages in vivo in animal model systems, b) construction of antisense oligonucleotides and siRNAs against inflammatory cytokines of macrophagic origin and c) to explore the therapeutic potential of curcumin, an herbal product, in the treatment of cancer and alcoholic liver disease.
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Rubin, M.D., Raphael
Professor Phone: 215-955-5031 Email: Raphael.Rubin@jefferson.edu
B.A., Boston University, 6-year Medical Program, 1979
M.D., Boston University School of Medicine, 1979
Surgical Pathology
Gastrointestinal/Liver pathology
Growth factor and tyrosine kinase signaling
Insulin-like growth factor receptor signaling
Effects of alcohol on cell signaling.
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Rubin, M.D., Emanuel
Gonzalo E. Aponte Professor Phone: (215) 955-5060 Email: Emanuel.Rubin@jefferson.edu
B.S., Villanova University, 1950
M.D., Harvard Medical School, 1954
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Schmidt, Richard R
Professor & Vice Chairman Phone: 215-503-7838 Email: Richard.R.Schmidt@jefferson.edu
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Schneider, Ph.D., Jay S.
Professor Phone: (215) 503-0370 Email: Jay.Schneider@jefferson.edu
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Schwaber, Ph.D., James S
Associate Professor Email: James.Schwaber@jefferson.edu
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Shea, J. Raymond
Associate Professor Phone: (215) 503-2880 Email: JRaymond.Shea@jefferson.edu
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Strayer, Marlene
Research Assistant Professor Email: Marlene.Strayer@jefferson.edu
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Strayer, M.D., Ph.D., David S.
Professor Phone: (215) 503-1087 Email: David.Strayer@jefferson.edu
M.D., University of Chicago
Ph.D., University of Chicago.
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Taraschi, Ph.D., Theodore F.
Professor & Vice Chair Phone: (215) 503-5020 Email: Theodore.Taraschi@jefferson.edu
Ph.D., Rutgers University, Chemistry, 1980. Vice Chair for Education, Department of Pathology, Anatomy & Cell Biology. Program Director, Cell & Developmental Biology Program
Areas of research include: 1) Elucidation of parasite protein trafficking pathways from intracellular parasites to the erythrocyte cytosol and host cell membrane. 2) Determinantion of the mechanism of hemoglobin uptake and transport by intraerythrocytic parasites. 3) Characterization of parasite DNA repair pathways (e.g. base excision and mismatch repair). Continued identification of the cellular components of these trafficking pathways to gain a better understanding of transport mechanisms in malaria-infected erythrocytes.
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Vadigepalli, Rajanikanth
Research Assistant Professor Phone: 215-955-0576 Email: raj@mail.dbi.tju.edu
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Witkiewicz, Agnieszka
Assistant Professor
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Wood, Moira
Assistant Professor Email: MOIRA.WOOD@jefferson.edu
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