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Department Chairman

Gorstein, M.D., Fred 
Professor, Chairman
Phone: 215-955-5060
Email: Fred.Gorstein@jefferson.edu

NYU, 1955.

Department Chair
279 Jefferson Alumni Hall
1020 Locust Street
Philadelphia, PA
19107
Phone: 215-955-5060

Department Faculty

Anni, Ph.D., Eleni 
Research Assistant Professor
Phone: (215) 955-5110
Email: eleni.anni@jefferson.edu

University of Patras, Greece, 1984. Biomarkers of alcoholism, anti-alcoholism drugs and proteomics.


Behling, Eric 
Assistant Professor


Bibbo, Marluce 
Professor
Phone: (215) 955-1197
Email: marluce.bibbo@mail.tju.edu


Bichenkov, Eugeney E
Research Assistant Professor
Email: Eugeney.Bichenkov@jefferson.edu


Birk, Ph.D., David E.
Professor
Phone: (215) 503-7855
Email: David.Birk@jefferson.edu

Wayne State, 1981. Developmental biology of extracellular matrix assembly in tendons and the cornea; mechanisms regulating collagen fibrillogenesis and tissue-specific fibril formation.


Cahill, Ph.D., Alan 
Associate Professor
Phone: (215) 955-0630
Email: Alan.Cahill@jefferson.edu

London, 1992. Mitochondrial dysfunction and alcoholic liver disease (ALD); relationship between ethanol-derived free radical production and hepatic mitochondrial DNA damage; protection by dietary supplements; role of aging in progression of ALD.


Covarrubias, M.D., Ph.D., Manuel L.
Professor
Phone: (215) 503-4341
Email: Manuel.Covarrubias@jefferson.edu

The structure, function and regulation of voltage-gated potassium channels

The long-term goal of our research is to gain mechanistic insights into the molecular basis of electrical signaling in neuronal and cardiac tissues. To reach this goal, we investigate two separate aspects: 1) the molecular physiology of somatodendritic potassium channels, and 2) the molecular architecture of a general anesthetic site in potassium channels.


Csordas, Gyorgy 
Research Assistant Professor
Email: Gyorgy.Csordas@jefferson.edu


Cunnane, Mary F
Associate Professor
Email: Mary.Cunnane@jefferson.edu


Curtis, Mark T.
Professor
Phone: (215) 955-5110
Email: Mark.Curtis@jefferson.edu


Edmonston, Tina 
Assistant Professor
Phone: 215-955-6373
Email: Tina.Edmonston@mail.tju.edu


Eisenman, Ph.D., Leonard M.
Professor
Phone: (215) 503-1686
Email: Leonard.Eisenman@jefferson.edu

Duke, 1974. Neuroscience: anatomical, developmental, and functional studies of the organization of the cerebellum with the use of rodents and neurologically mutant mice, with an emphasis on development of the topographic and synaptic organization of afferent systems to the cerebellum.


Ellingson, Ph.D., John S.
Associate Professor
Phone: (215) 503-5021
Email: John.Ellingson@jefferson.edu

Michigan, 1967. To gain information relevant for correcting myelin-associated pathologies, e.g., multiple sclerosis or fetal alcohol syndrome, we are investigating the molecular and cellular regulation of myelin formation in differentiating oligodendrocytes, with an emphasis on identifying 1) the roles of protein kinase C (PKC) isozymes and 2) the ethanol-affected regulatory systems.


Farber, M.D., John L.
Professor
Phone: (215) 503-5066
Email: John.Farber@jefferson.edu

Professor; M.D., University of California (San Francisco), 1966. Biochemical mechanisms of cell injury in ischemia of liver cell necrosis; biochemical toxicology of activated oxygen; chemical carcinogenesis.


Fenderson, Ph.D., Bruce A.
Associate Professor
Phone: 215-503-2256
Email: Bruce.Fenderson@jefferson.edu

Johns Hopkins, 1980. Mechanisms of morphogenesis and malignancy; role of cell-surface carbohydrates in mediation of cell recognition during development; use of monoclonal anticarbohydrate antibodies to study lineage formation, cell differentiation, and neoplastic transformation.


Gonye, Ph.D., Gregory E.
Research Assistant Professor
Phone: (215) 955-0580
Email: ggonye@mail.dbi.tju.edu

Connecticut, 1993. Molecular neuroscience: role of transcriptional regulation in neuromodulation, concentrating on nucleus tractus solitarius neurons, neuropeptides (angiotensin II), and RGS proteins; effects of ethanol on neuromodulation; development of computational approaches to study neuromodulation, including modeling and simulation and bioinformatic tools.


Grunwald, Ph.D., Gerald B.
Professor & Associate Dean
Phone: (215) 503-4191
Email: Gerald.Grunwald@jefferson.edu

Professor; Ph.D., Wisconsin, 1981. Developmental biology and neuroscience; eye development and disease, analysis of the role of cadherin cell adhesion molecules in normal and abnormal embryonic development and in proliferative diseases of the nervous mechanisms of cadherin expression and function.


Gulati, Gene L.
Professor
Phone: (215) 955-2682
Email: Gene.Gulati@jefferson.edu


Hajnoczky, Ph.D., Gyorgy 
Professor
Phone: (215) 503-1427
Email: Gyorgy.Hajnoczky@jefferson.edu

Semmelweis, Budapest, 1987; Ph.D., National Academy of Sciences, Hungary, 1995. Intracellular calcium signaling; inositol trisphosphate-linked hormones; organization of calcium mobilization from endoplasmic/sarcoplasmic reticulum; mitochondrial calcium signaling; calcium-dependent control over life and death of cells; fluorometric, fluorescence microscope imaging and electrophysiological approaches.


Ho, Cojen 
Research Assistant Professor
Phone: (215) 503-4034
Email: Cojen.Ho@jefferson.edu


Hoek, Ph.D., Jan B.
Professor & Vice Chair
Phone: (215) 503-5016
Email: Jan.Hoek@jefferson.edu

Amsterdam, 1972. Systems biology of intracellular signal transduction networks; deregulation of cytokine and growth factor signaling in the liver associated with chronic alcohol consumption; early signaling responses during liver regeneration; bioenergetics and mitochondrial metabolism and its role in intracellular signaling and apoptosis.


Iozzo, M.D., Ph.D., Renato V.
Professor & Director, Extracellular Matrix Program
Phone: (215) 503-2208
Email: Renato.Iozzo@jefferson.edu

Florence, 1975. Biosynthesis, structure, and metabolism of proteoglycans in normal and malignant cells; analysis of the cell-surface heparin sulfate proteoglycan synthesized by human colon carcinoma cells, and the regulation of molecular assembly, posttranslational modifications, and turnover of this class of macromolecules; interactions between malignant epithelial cells and normal mesenchymal cells in vitro and the effects on extracellular matrix gene expression.


Joseph, Ph.D., Suresh K.
Professor
Phone: (215) 503-1221
Email: Suresh.Joseph@jefferson.edu

Bristol (England). Structure, function, and regulation of the inositol trisphosphate receptor (IP3R); biosynthesis and assembly of IP3R homo- and heteroligomers; mechanisms of proteosomal and lysosomal degradation of IP3R.


Jungkind, Donald L
Professor
Email: Donald.Jungkind@jefferson.edu


Kaulin, Yuri A
Research Assistant Professor
Email: Yuri.Kaulin@jefferson.edu


Kenyon, Lawrence C.
Associate Professor
Phone: (215) 955-2071
Email: Lawrence.Kenyon@jefferson.edu


Kholodenko, Ph.D., Boris N.
Research Professor
Phone: (215) 503-1614
Email: Boris.Kholodenko@jefferson.edu

Moscow, 1976. Systems biology; quantitative analysis of spatio-temporal dynamics of cellular signaling and gene networks through biochemical, molecular biological, genetic, and computational cell biology methods.


Kiyatkin, Anatoly 
Research Assistant Professor
Phone: (215) 503-4794
Email: Anatoly.Kiyatkin@jefferson.edu


Kocher, William D.
Clinical Assistant Professor
Phone: (215) 966-6725
Email: William.Kocher@jefferson.edu


Kuo, Bruce A
Instructor
Email: Bruce.Kuo@jefferson.edu


Lian, Zhaorui 
Research Assistant Professor
Phone: 215-503-1037
Email: Zhaorui.Lian@jefferson.edu


Markevitch, Nikolai 
Instructor
Email: Nikolai.Markevitch@jefferson.edu


Mc Closkey, Laura 
Clinical Assistant Professor
Phone: 215-955-1414
Email: Laura.McCloskey@jefferson.edu


McCue, Peter A.
Professor
Phone: (215) 955-5588
Email: Peter.McCue@jefferson.edu

CUNY, Mount Sinai, 1977. Clinical and experimental pathobiology of neoplasia: effects of retinoids on the differentiation of germ cells and related tumors; role of nuclear receptors and cytosolic-binding proteins for retinoic acid in differentiation-defective cell lines.


Menko, Ph.D., A. Sue
Professor
Phone: (215) 503-2166
Email: sue.menko@jefferson.edu

Pennsylvania, 1978. Role of integrins in the regulation of cell differentiation: Integrin signalling of cell differentiation events, particularly integrin-growth factor receptor coordinated signalling.


O'Hara, Brian J.
Associate Professor
Phone: 215-955-4404
Email: brian.ohara@jefferson.edu


O'Leary, Michael E.
Research Assistant Professor
Phone: (215) 503-9983
Email: Michael.O'Leary@mail.tju.edu


Palazzo, Juan P.
Professor
Phone: (215) 955-6352
Email: Juan.Palazzo@jefferson.edu


Philp, Ph.D., Nancy J.
Associate Professor
Phone: 215-503-7854
Email: Nancy.Philp@jefferson.edu


Ponnappa, Ph.D., Biddanda C.
Associate Professor
Phone: (215) 503-5018
Email: biddanda.ponnappa@jefferson.edu

Current research interests include a) development of liposome-mediated drug delivery system to target macrophages in vivo in animal model systems, b) construction of antisense oligonucleotides and siRNAs against inflammatory cytokines of macrophagic origin and c) to explore the therapeutic potential of curcumin, an herbal product, in the treatment of cancer and alcoholic liver disease.


Rubin, M.D., Raphael 
Professor
Phone: 215-955-5031
Email: Raphael.Rubin@jefferson.edu

B.A., Boston University, 6-year Medical Program, 1979 M.D., Boston University School of Medicine, 1979 Surgical Pathology Gastrointestinal/Liver pathology Growth factor and tyrosine kinase signaling Insulin-like growth factor receptor signaling Effects of alcohol on cell signaling.


Rubin, M.D., Emanuel 
Gonzalo E. Aponte Professor
Phone: (215) 955-5060
Email: Emanuel.Rubin@jefferson.edu

B.S., Villanova University, 1950 M.D., Harvard Medical School, 1954


Schmidt, Richard R
Professor & Vice Chairman
Phone: 215-503-7838
Email: Richard.R.Schmidt@jefferson.edu


Schneider, Ph.D., Jay S.
Professor
Phone: (215) 503-0370
Email: Jay.Schneider@jefferson.edu


Schwaber, Ph.D., James S
Associate Professor
Email: James.Schwaber@jefferson.edu


Shea, J. Raymond 
Associate Professor
Phone: (215) 503-2880
Email: JRaymond.Shea@jefferson.edu


Strayer, Marlene 
Research Assistant Professor
Email: Marlene.Strayer@jefferson.edu


Strayer, M.D., Ph.D., David S.
Professor
Phone: (215) 503-1087
Email: David.Strayer@jefferson.edu

M.D., University of Chicago Ph.D., University of Chicago.


Taraschi, Ph.D., Theodore F.
Professor & Vice Chair
Phone: (215) 503-5020
Email: Theodore.Taraschi@jefferson.edu

Ph.D., Rutgers University, Chemistry, 1980. Vice Chair for Education, Department of Pathology, Anatomy & Cell Biology. Program Director, Cell & Developmental Biology Program

Areas of research include:
1) Elucidation of parasite protein trafficking pathways from intracellular parasites to the erythrocyte cytosol and host cell membrane.
2) Determinantion of the mechanism of hemoglobin uptake and transport by intraerythrocytic parasites.
3) Characterization of parasite DNA repair pathways (e.g. base excision and mismatch repair). Continued identification of the cellular components of these trafficking pathways to gain a better understanding of transport mechanisms in malaria-infected erythrocytes.


Vadigepalli, Rajanikanth 
Research Assistant Professor
Phone: 215-955-0576
Email: raj@mail.dbi.tju.edu


Witkiewicz, Agnieszka 
Assistant Professor


Wood, Moira 
Assistant Professor
Email: MOIRA.WOOD@jefferson.edu





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