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Anni, Ph.D., Eleni
Research Assistant Professor
Phone: (215) 955-5110
Email: eleni.anni@jefferson.edu
University of Patras, Greece, 1984. Biomarkers of alcoholism, anti-alcoholism drugs and proteomics.
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Behling, Eric
Assistant Professor
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Bibbo, Marluce
Professor
Phone: 215-955-1197
Email: marluce.bibbo@jefferson.edu
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Bichenkov, Eugeney E
Research Assistant Professor
Email: Eugeney.Bichenkov@jefferson.edu
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Birk, Ph.D., David E.
Professor
Phone: (215) 503-7855
Email: David.Birk@jefferson.edu
Wayne State, 1981. Developmental biology of extracellular matrix assembly in tendons and the cornea; mechanisms regulating collagen fibrillogenesis and tissue-specific fibril formation.
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Cahill, Ph.D., Alan
Associate Professor
Phone: (215) 955-0630
Email: Alan.Cahill@jefferson.edu
London, 1992. Mitochondrial dysfunction and alcoholic liver disease (ALD); relationship between ethanol-derived free radical production and hepatic mitochondrial DNA damage; protection by dietary supplements; role of aging in progression of ALD.
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Covarrubias, M.D., Ph.D., Manuel L.
Professor
Phone: (215) 503-4341
Email: Manuel.Covarrubias@jefferson.edu
The structure, function and regulation of voltage-gated potassium channels
The long-term goal of our research is to gain mechanistic insights into the
molecular basis of electrical signaling in neuronal and cardiac tissues. To
reach this goal, we investigate two separate aspects: 1) the molecular
physiology of somatodendritic potassium channels, and 2) the molecular
architecture of a general anesthetic site in potassium channels.
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Csordas, Gyorgy
Research Assistant Professor
Email: Gyorgy.Csordas@jefferson.edu
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Cunnane, Mary F
Associate Professor
Email: Mary.Cunnane@jefferson.edu
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Curtis, Mark T.
Professor
Phone: (215) 955-5110
Email: Mark.Curtis@jefferson.edu
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Edmonston, Tina
Assistant Professor
Phone: 215-955-6373
Email: Tina.Edmonston@mail.tju.edu
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Eisenman, Ph.D., Leonard M.
Professor
Phone: (215) 503-1686
Email: Leonard.Eisenman@jefferson.edu
Duke, 1974. Neuroscience: anatomical, developmental, and functional studies of the organization of the cerebellum with the use of rodents and neurologically mutant mice, with an emphasis on development of the topographic and synaptic organization of afferent systems to the cerebellum.
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Ellingson, Ph.D., John S.
Associate Professor
Phone: (215) 503-5021
Email: John.Ellingson@jefferson.edu
Michigan, 1967. To gain information relevant for correcting myelin-associated pathologies, e.g., multiple sclerosis or fetal alcohol syndrome, we are investigating the molecular and cellular regulation of myelin formation in differentiating oligodendrocytes, with an emphasis on identifying 1) the roles of protein kinase C (PKC) isozymes and 2) the ethanol-affected regulatory systems.
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Farber, M.D., John L.
Professor
Phone: (215) 503-5066
Email: John.Farber@jefferson.edu
Professor; M.D., University of California (San Francisco), 1966. Biochemical mechanisms of cell injury in ischemia of liver cell necrosis; biochemical toxicology of activated oxygen; chemical carcinogenesis.
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Fenderson, Ph.D., Bruce A.
Associate Professor
Phone: 215-503-2256
Email: Bruce.Fenderson@jefferson.edu
Johns Hopkins, 1980. Mechanisms of morphogenesis and malignancy; role of cell-surface carbohydrates in mediation of cell recognition during development; use of monoclonal anticarbohydrate antibodies to study lineage formation, cell differentiation, and neoplastic transformation.
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Goldoni, Silvia
Phone: 215-503-5009
Email: Silvia.Goldoni@jefferson.edu
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Gonye, Ph.D., Gregory E.
Research Assistant Professor
Phone: (215) 955-0580
Email: ggonye@mail.dbi.tju.edu
Connecticut, 1993. Molecular neuroscience: role of transcriptional regulation in neuromodulation, concentrating on nucleus tractus solitarius neurons, neuropeptides (angiotensin II), and RGS proteins; effects of ethanol on neuromodulation; development of computational approaches to study neuromodulation, including modeling and simulation and bioinformatic tools.
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Gorstein, M.D., Fred
Professor
Phone: 215-955-5060
Email: Fred.Gorstein@jefferson.edu
NYU, 1955.
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Grunwald, Ph.D., Gerald B.
Professor & Associate Dean
Phone: (215) 503-4191
Email: Gerald.Grunwald@jefferson.edu
Professor; Ph.D., Wisconsin, 1981. Developmental biology and neuroscience; eye development and disease, analysis of the role of cadherin cell adhesion molecules in normal and abnormal embryonic development and in proliferative diseases of the nervous mechanisms of cadherin expression and function.
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Gulati, Gene L.
Professor
Phone: (215) 955-2682
Email: Gene.Gulati@jefferson.edu
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Hajnoczky, M.D., Ph.D., Gyorgy
Professor
Phone: (215) 503-1427
Email: Gyorgy.Hajnoczky@jefferson.edu
Semmelweis, Budapest, 1987; Ph.D., National Academy of Sciences, Hungary, 1995. Intracellular calcium signaling; inositol trisphosphate-linked hormones; organization of calcium mobilization from endoplasmic/sarcoplasmic reticulum; mitochondrial calcium signaling; calcium-dependent control over life and death of cells; fluorometric, fluorescence microscope imaging and electrophysiological approaches.
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Ho, Cojen
Research Assistant Professor
Phone: (215) 503-4034
Email: Cojen.Ho@jefferson.edu
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Hoek, Ph.D., Jan B.
Professor & Vice Chair
Phone: (215) 503-5016
Email: Jan.Hoek@jefferson.edu
Amsterdam, 1972. Systems biology of intracellular signal transduction networks; deregulation of cytokine and growth factor signaling in the liver associated with chronic alcohol consumption; early signaling responses during liver regeneration; bioenergetics and mitochondrial metabolism and its role in intracellular signaling and apoptosis.
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Iozzo, M.D., Renato V.
Professor & Director, Extracellular Matrix Program
Phone: 215-503-2208
Email: Iozzo@mail.jci.tju.edu
Professor of Pathology and Cell Biology, and Director of the Extracellular Matrix Program at the Kimmel Cancer Center, Thomas Jefferson University. After receiving an M.D. degree summa cum laude from the University of Florence, Italy, he moved to the Department of Pathology at the University of Washington, where he completed a five-year Residency/Fellowship. Following a six-year faculty appointment at the University of Pennsylvania, he moved to Thomas Jefferson University. Dr. Iozzo has received many awards including the Benjamin Castleman Award from the International Academy of Pathology, the Junior Faculty Research Award from the American Cancer Society, the Burlington Resources Foundation Faculty Achievement Award, and the Faculty Research Award from the American Cancer Society. In 2008, Dr. Iozzo received an Honorary Professorship at the School of Life Sciences, University of Manchester, UK. His research focuses on the biology of proteoglycans and their roles in cancer and angiogenesis.
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Joseph, Ph.D., Suresh K.
Professor
Phone: (215) 503-1221
Email: Suresh.Joseph@jefferson.edu
Bristol (England). Structure, function, and regulation of the inositol trisphosphate receptor (IP3R); biosynthesis and assembly of IP3R homo- and heteroligomers; mechanisms of proteosomal and lysosomal degradation of IP3R.
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Jungkind, Donald L
Professor
Email: Donald.Jungkind@jefferson.edu
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Kaulin, Yuri A
Research Assistant Professor
Email: Yuri.Kaulin@jefferson.edu
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Kenyon, Lawrence C.
Associate Professor
Phone: (215) 955-2071
Email: Lawrence.Kenyon@jefferson.edu
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Kholodenko, Ph.D., Boris N.
Research Professor
Phone: (215) 503-1614
Email: Boris.Kholodenko@jefferson.edu
Moscow, 1976. Systems biology; quantitative analysis of spatio-temporal dynamics of cellular signaling and gene networks through biochemical, molecular biological, genetic, and computational cell biology methods.
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Kiyatkin, Anatoly
Research Assistant Professor
Phone: (215) 503-4794
Email: Anatoly.Kiyatkin@jefferson.edu
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Kocher, William D.
Clinical Assistant Professor
Phone: (215) 966-6725
Email: William.Kocher@jefferson.edu
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Kuo, Bruce A
Instructor
Email: Bruce.Kuo@jefferson.edu
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Lian, Zhaorui
Research Assistant Professor
Phone: 215-503-1037
Email: Zhaorui.Lian@jefferson.edu
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Lopez, Hector
Phone: 215-503-6633
Email: Hector.Lopez@jefferson.edu
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Markevitch, Nikolai
Instructor
Email: Nikolai.Markevitch@jefferson.edu
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Mc Closkey, Laura
Clinical Assistant Professor
Phone: 215-955-1414
Email: Laura.McCloskey@jefferson.edu
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McCue, Peter A.
Professor
Phone: (215) 955-5588
Email: Peter.McCue@jefferson.edu
CUNY, Mount Sinai, 1977. Clinical and experimental pathobiology of neoplasia: effects of retinoids on the differentiation of germ cells and related tumors; role of nuclear receptors and cytosolic-binding proteins for retinoic acid in differentiation-defective cell lines.
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Menko, Ph.D., A. Sue
Professor
Phone: (215) 503-2166
Email: sue.menko@jefferson.edu
Pennsylvania, 1978. Role of integrins in the regulation of cell differentiation: Integrin signalling of cell differentiation events, particularly integrin-growth factor receptor coordinated signalling.
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O'Hara, Brian J.
Associate Professor
Phone: 215-955-4404
Email: brian.ohara@jefferson.edu
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O'Leary, Michael E.
Research Assistant Professor
Phone: (215) 503-9983
Email: Michael.O'Leary@mail.tju.edu
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Palazzo, Juan P.
Professor
Phone: (215) 955-6352
Email: Juan.Palazzo@jefferson.edu
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Philp, Ph.D., Nancy J.
Associate Professor
Phone: 215-503-7854
Email: Nancy.Philp@jefferson.edu
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Ponnappa, Ph.D., Biddanda C.
Associate Professor
Phone: (215) 503-5018
Email: biddanda.ponnappa@jefferson.edu
Current research interests include a) development of liposome-mediated drug delivery system to target macrophages in vivo in animal model systems, b) construction of antisense oligonucleotides and siRNAs against inflammatory cytokines of macrophagic origin and c) to explore the therapeutic potential of curcumin, an herbal product, in the treatment of cancer and alcoholic liver disease.
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Rubin, M.D., Raphael
Professor
Phone: 215-955-5031
Email: Raphael.Rubin@jefferson.edu
B.A., Boston University, 6-year Medical Program, 1979
M.D., Boston University School of Medicine, 1979
Surgical Pathology
Gastrointestinal/Liver pathology
Growth factor and tyrosine kinase signaling
Insulin-like growth factor receptor signaling
Effects of alcohol on cell signaling.
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Rubin, M.D., Emanuel
Gonzalo E. Aponte Professor
Phone: (215) 955-5060
Email: Emanuel.Rubin@jefferson.edu
B.S., Villanova University, 1950
M.D., Harvard Medical School, 1954
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Schmidt, Richard R
Professor & Vice Chairman
Phone: 215-503-7838
Email: Richard.R.Schmidt@jefferson.edu
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Schneider, Ph.D., Jay S.
Professor
Phone: (215) 503-0370
Email: Jay.Schneider@jefferson.edu
Focus: Basic, clinical and translational research on on cognitive and motor aspects of Parkinson''s disease with focuses on both symptomatic and neuroprotective treatment strategies; basic and clinical research on developmental neurotoxicology with an emphasis on lead-induced damage to the brain.
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Schwaber, Ph.D., James S
Associate Professor
Email: James.Schwaber@jefferson.edu
Director of Daniel Baugh Institute for Functional Genomics and Computational Biology; Department of Pathology, Anatomy & Cell Biology
Adjunct Professor Chemical Engineering, University of Delaware
Dr. Schwaber uses systems biology approaches in mammalian brain to study adaptive neuronal processes. Specifically his interests involve mechanisms by which hypertension arises in homeostatic cardiorespiratory regulatory circuits, by which the symptoms of alcohol withdrawal are produced and by which phase shifting of light causes the brain''s master clock to reorganize circadian behavior.
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Shea, J. Raymond
Associate Professor
Phone: (215) 503-2880
Email: JRaymond.Shea@jefferson.edu
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Strayer, Marlene
Research Assistant Professor
Email: Marlene.Strayer@jefferson.edu
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Strayer, M.D., Ph.D., David S.
Professor
Phone: (215) 503-1087
Email: David.Strayer@jefferson.edu
M.D., University of Chicago
Ph.D., University of Chicago.
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Taraschi, Ph.D., Theodore F.
Professor & Vice Chair
Phone: (215) 503-5020
Email: Theodore.Taraschi@jefferson.edu
Ph.D., Rutgers University, Chemistry, 1980. Vice Chair for Education, Department of Pathology, Anatomy & Cell Biology. Program Director, Cell & Developmental Biology Program
Areas of research include:
1) Elucidation of parasite protein trafficking pathways from intracellular parasites to the erythrocyte cytosol and host cell membrane.
2) Determinantion of the mechanism of hemoglobin uptake and transport by intraerythrocytic parasites.
3) Characterization of parasite DNA repair pathways (e.g. base excision and mismatch repair). Continued identification of the cellular components of these trafficking pathways to gain a better understanding of transport mechanisms in malaria-infected erythrocytes.
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Vadigepalli, Rajanikanth
Research Assistant Professor
Phone: 215-955-0576
Email: raj@mail.dbi.tju.edu
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Witkiewicz, Agnieszka
Assistant Professor
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Wood, Moira
Assistant Professor
Email: MOIRA.WOOD@jefferson.edu
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