Thomas Jefferson University - Anatoly Kiyatkin, Ph.D.
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Qualifications
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Ph.D., Moscow Institute of Physics and Technology, Biophysics, 1986
M.S., Moscow Institute of Physics and Technology, Biophysics, 1983
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Keywords
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Quantitative analysis of signal transduction networks; Determination of protein structures by X-ray crystallography; Molecular modeling of 3-D structures of biomolecules; Kinetics of protein-protein interactions by BIAcore; Expression and purification of proteins; Production of vaccines using plant virus technology;
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Publications
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- A. Suenaga, M. Hatakeyama, A. B. Kiyatkin, R. Radhakrishnan, M. Taiji, and B. N. Kholodenko Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptor. Biophys. J., 2008 (in press).
- Anatoly Kiyatkin, Edita Aksamitiene. Multi-strip Western blotting to increase quantitative data output. In: Protein Blotting and Detection: Methods and Protocols (Methods in Molecular Biology) , Editors R. Hal Scofield, Biji Kurien. Humana Press, Totowa, NJ, 2008 (in press)
- Mamikonyan G, Kiyatkin A, Movsesyan N., Mkrtichyan M, Ghochikyan A, Petrushina I, Hwang J., Ichim T.E., Agadjanyan M.G. Detection of active components of calf thymus nuclear proteins (TNP), Histones that are binding with high affitinty to HIV-1 envelope proteins and CD4 molecules. Current HIV Research, 6(4):318-26, 2008.
- Aksamitiene E, Hoek, J. B., Kholodenko, B. N., Kiyatkin, A. B. Multi-strip Western blotting to increase quantitative data output. Electrophoresis. 28(18):3163-73, 2007.
- Mamikonyan G, Necula M, Mkrtichyan M, Ghochikyan A, Petrushina I, Movsesyan N, Mina E, Kiyatkin A, Glabe CG, Cribbs DH, Agadjanyan MG. Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers. J. Biol. Chem. 282(31):22376-86, 2007.
- Kiyatkin, A. B., Aksamitiene E, Markevich, N. I., Borisov, N. M., Hoek, J. B. & Kholodenko, B. N. Scaffolding protein GAB1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops. J. Biol. Chem. 281: 19925-19938, 2006.
- Sontag E, Kiyatkin A, Kholodenko BN. Inferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data. Bioinformatics. 20(12):1877-86, 2004.
- Markevich N.I., Moehren G., Demin O., Kiyatkin A., Hoek J., Kholodenko B. Signal Processing At The Ras Circuit: What Shapes Ras Activation Patterns? IEE Systems Biology. 1(1):104-113, 2004.
- Suenaga A, Kiyatkin AB, Hatakeyama M, Futatsugi N, Okimoto N, Hirano Y, Narumi T, Kawai A, Susukita R, Koishi T, Furusawa H, Yasuoka K, Takada N, Ohno Y, Taiji M, Ebisuzaki T, Hoek JB, Konagaya A, Kholodenko BN. Tyr-317 phosphorylation increases Shc structural rigidity and reduces coupling of domain motions remote from the phosphorylation site as revealed by molecular dynamics simulations. J Biol Chem. 279(6): 4657-62, 2004
- Verch T, Hooper DC, Kiyatkin A, Steplewski Z, Koprowski H. Immunization with a plant-produced colorectal cancer antigen. Cancer Immunol Immunother. 53(2): 92-9, 2004
- Kholodenko BN, Kiyatkin A, Bruggeman FJ, Sontag E, Westerhoff HV, Hoek JB. Untangling the wires: a strategy to trace functional interactions in signaling and gene networks. Proc Natl Acad Sci USA. 99(20): 12841-6, 2002
- Moehren G, Markevich N, Demin O, Kiyatkin A, Goryanin I, Hoek JB, Kholodenko BN. Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model. Biochemistry. 41(1): 306-20, 2002
- Zhang D., Kiyatkin A., Bolin J.T., Low P.S. Crystallographic Structure and Functional Interpretation of the Cytoplasmic Domain of Erythrocyte Membrane Band 3. Blood. 96(9): 2925-2933, 2000
- Li Q, Jungmann V, Kiyatkin A, Low PS. Prostaglandin E2 stimulates a Ca2 -dependent K channel in human erythrocytes and alters cell volume and filterability. Journal of Biological Chemistry. 271(31): 18651-6, Aug 1996
- Kiyatkin AB, Natarajan P, Munshi S, Minor W, Johnson JE, Low PS. Crystallization and preliminary X-ray analysis of the cytoplasmic domain of human erythrocyte band 3. Proteins. 22(3): 293-7, Jul 1995
- P. Low, A. Kiyatkin, Q. Li, M. Harrison. Control of erythrocyte metabolism by redox-regulated tyrosine phosphatases and kinases. Protoplasma. 184: 196-202, 1995
- A. Zhabotinsky, F. Buchholtz, A. Kiyatkin, I. Epstein. Oscillations and waves in metal-ion catalyzed bromate oscillating reactions in highly oxidized states. Journal of Physical Chemistry. 97: 7578-7584, 1993
- F. Ataullakhanov, A. Kiyatkin, V. Vitvitsky, A. Pichugin. Volume regulation in human erythrocyte. The role of potassium channels activated by calcium. Biological Membranes (Moscow). 10: 597-603, 1993
- F. Ataullakhanov, V. Vitvitsky, A. Kiyatkin, A. Pichugin. Regulation of the volume of human erythrocytes. Role of calcium-activated potassium channels. Biofizika. 38: 833-844, 1993
- G. Guriya, A. Kiyatkin, S. Muller. Splitting of the autowave in the Belousov-Zhabotinsky chemical system. Biofizika. 38: 461-465, 1993
- I. Moroz, F. Ataullakhanov, A. Pichugin, A. Kiyatkin, V. Vitvitsky. Mathematical model of erythrocyte volume stabilization. Biological Membranes (Moscow). 6: 409-419, 1989
- F. Ataullakhanov, V. Vitvitsky, A. Zhabotinsky, A. Kiyatkin, A. Pichugin, E. Sinauridze. Metabolic changes leading to the oxidative lysis of erythrocytes maintained in a normal state in vitro. Biochemistry (Moscow). 51: 1345-1352, 1986
- F. Ataullakhanov, V. Vitvitsky, A. Zhabotinsky, A. Kiyatkin, A. Pichugin. Steady-state dependence of rate of reduction of methemoglobin on its concentration in intact human erythrocytes. Biochemistry (Moscow). 49: 150-154, 1984
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Individual Expertise profile of
Anatoly Kiyatkin, Ph.D., Copyright © Anatoly Kiyatkin, Ph.D..
Last Updated
by Admin
: Thursday, September 3, 2009 10:12:07 AM
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