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Thomas Jefferson University - Fred Gorstein, M.D.
Fred Gorstein, M.D.

Pathology, Anatomy and Cell Biology
Thomas Jefferson University
Jefferson Medical College
Department of Pathology
Anatomy & Cell Biology
Professor & Chairman

Mailing Address

Philadelphia, Pennsylvania 19107
United States
Contact Information
Phone: 215-503-7602
Fred.Gorstein@jefferson.edu
Keywords
Pathology
Publications
  • Bruner KL, Matrisian LM, Rodgers WH, Gorstein F, Osteen KG. Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. Journal of Clinical Investigation. 99(12): 2851-7, Jun 1997

  • Osteen KG, Rodgers WH, Gaire M, Hargrove JT, Gorstein F, Matrisian LM. Stromal-epithelial interaction mediates steroidal regulation of metalloproteinase expression in human endometrium. Proceedings of the National Academy of Sciences (USA). 91(21): 10129-33, Oct 1994

  • Rodgers WH, Matrisian LM, Giudice LC, Dsupin B, Cannon P, Svitek C, Gorstein F, Osteen KG. Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones. Journal of Clinical Investigation. 94(3): 946-53, Sep 1994

  • Rodgers WH, Osteen KG, Matrisian LM, Navre M, Giudice LC, Gorstein F. Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle. American Journal of Obstetrics and Gynecology. 168(1 Pt 1): 253-60, Jan 1993

  • Anderson RE, Hill RB, Gorstein F. A model for the autopsy-based quality assessment of medical diagnostics. Archives of Pathology and Laboratory Medicine. 114(11): 1163, Nov 1990

  • Osteen KG, Anderson TL, Hargrove JT, Hill GA, Gorstein F. Epithelial cells from normal human endometrium express a tumor-associated glycoprotein (TAG-72) epitope in vitro. American Journal of Obstetrics and Gynecology. 163(2): 479-84, Aug 1990

  • Anderson TL, Gorstein F, Osteen KG. Stromal-epithelial cell communication, growth factors, and tissue regulation. Laboratory Investigation. 62(5): 519-21, May 1990

  • Osteen KG, Hill GA, Hargrove JT, Gorstein F. Development of a method to isolate and culture highly purified populations of stromal and epithelial cells from human endometrial biopsy specimens. Fertility and Sterility. 52(6): 965-72, Dec 1989

  • Thor A, Muraro R, Gorstein F, Ohuchi N, Viglione M, Szpak CA, Johnston WW, Schlom J. Adjunct to the diagnostic distinction between adenocarcinomas of the ovary and the colon utilizing a monoclonal antibody (COL-4) with restricted carcinoembryonic antigen reactivity. Cancer Research. 47(2): 505-12, Jan 1987

  • Thor A, Viglione MJ, Muraro R, Ohuchi N, Schlom J, Gorstein F. Monoclonal antibody B72.3 reactivity with human endometrium: a study of normal and malignant tissues. International Journal of Gynecological Pathology. 6(3): 235-47, 1987

  • Thor A, Gorstein F, Ohuchi N, Szpak CA, Johnston WW, Schlom J. Tumor-associated glycoprotein (TAG-72) in ovarian carcinomas defined by monoclonal antibody B72.3. Journal of the National Cancer Institute. 76(6): 995-1006, Jun 1986

  • Day CL Jr, Mihm MC Jr, Sober AJ, Harris MN, Kopf AW, Fitzpatrick TB, Lew RA, Harrist TJ, Golomb FM, Postel A, Hennessey P, Gumport SL, Raker JW, Malt RA, Cosimi AB, Wood WC, Roses DF, Gorstein F, Rigel D, Friedman RJ, Mintzis MM. Predictors of late deaths among patients with clinical stage I melanoma who have not had bony or visceral metastases within the first 5 years after diagnosis. Journal of the American Academy of Dermatology. 8(6): 864-8, Jun 1983

  • Day CL Jr, Mihm MC Jr, Lew RA, Harris MN, Kopf AW, Fitzpatrick TB, Harrist TJ, Golomb FM, Postel A, Hennessey P, Gumport SL, Raker JW, Malt RA, Cosimi AB, Wood WC, Roses DF, Gorstein F, Rigel D, Friedman RJ, Mintzis MM, Sober AJ. Prognostic factors for patients with clinical stage I melanoma of intermediate thickness (1.51 - 3.39 mm). A conceptual model for tumor growth and metastasis. Annals of Surgery. 195(1): 35-43, Jan 1982

  • Day CL Jr, Lew RA, Mihm MC Jr, Sober AJ, Harris MN, Kopf AW, Fitzpatrick TB, Harrist TJ, Golomb FM, Postel A, Hennessey P, Gumport SL, Raker JW, Malt RA, Cosimi AB, Wood WC, Roses DF, Gorstein F, Rigel D, Friedman RJ, Mintzis MM, Grier RW. A multivariate analysis of prognostic factors for melanoma patients with lesions greater than or equal to 3.65 mm in thickness. The importance of revealing alternative Cox models. Annals of Surgery. 195(1): 44-9, Jan 1982

  • Day CL Jr, Mihm MC Jr, Sober AJ, Harris MN, Kopf AW, Fitzpatrick TB, Lew RA, Harrist TJ, Golomb FM, Postel A, Hennessey P, Gumport SL, Raker JW, Malt RA, Cosimi AB, Wood WC, Roses DF, Gorstein F, Rigel D, Friedman RJ, Mintzis MM. Prognostic factors for melanoma patients with lesions 0.76 - 1.69 mm in thickness. An appraisal of 'thin' level IV lesions. Annals of Surgery. 195(1): 30-4, Jan 1982

  • Day CL Jr, Harrist TJ, Gorstein F, Sober AJ, Lew RA, Friedman RJ, Pasternack BS, Kopf AW, Fitzpatrick TB, Mihm MC Jr. Malignant melanoma. Prognostic significance of 'microscopic satellites' in the reticular dermis and subcutaneous fat. Annals of Surgery. 194(1): 108-12, Jul 1981

  • Day CL Jr, Sober AJ, Kopf AW, Lew RA, Mihm MC Jr, Golomb FM, Hennessey P, Harris MN, Gumport SL, Raker JW, Malt RA, Cosimi AB, Wood WC, Roses DF, Gorstein F, Fitzpatrick TB, Postel A. A prognostic model for clinical stage I melanoma of the lower extremity. Location on foot as independent risk factor for recurrent disease. Surgery. 89(5): 599-603, May 1981

  • Day CL Jr, Sober AJ, Lew RA, Mihm MC Jr, Fitzpatrick TB, Kopf AW, Harris MN, Gumport SL, Raker JW, Malt RA, Golomb FM, Cosimi AB, Wood WC, Casson P, Lopransi S, Gorstein F, Postel A. Malignant melanoma patients with positive nodes and relatively good prognoses: microstaging retains prognostic significance in clinical stage I melanoma patients with metastases to regional nodes. Cancer. 47(5): 955-62, Mar 1981

  • Roses DF, Harris MN, Gorstein F, Gumport SL. Biopsy for microcalcification detected by mammography. Surgery. 87(3): 248-52, Mar 1980

  • Imparato AM, Riles TS, Gorstein F. The carotid bifurcation plaque: pathologic findings associated with cerebral ischemia. Stroke. 10(3): 238-45, 1979

  • Edwards JH, Kricheff II, Gorstein F, Riles T, Imparato A. Atherosclerotic subintimal hematoma of the carotid artery. Radiology. 133(1): 123-9, Oct 1979

  • Chalon J, Tang CK, Gorstein F, Turndorf H, Katz JS, Klein GS, Patel C. Diagnostic and prognostic significance of tracheobronchial epithelial multinucleation. Acta Cytologica. 22(5): 316-20, 1978

  • Culliford AT, Isom OW, Trehan NK, Doyle E, Gorstein F, Spencer FC. Benign tumors of right atrium necessitating extensive resection and reconstruction. Journal of Thoracic and Cardiovascular Surgery. 76(2): 178-82, Aug 1978

  • Friedman-Mor Z, Chalon J, Gorstein F, Turndorf H, Chuba JV, Orkin LR. Abnormal heme-protein patterns in hemorrhagic shock. Journal of Trauma. 18(2): 104-7, Feb 1978

  • Dancis J, Jansen V, Brown GF, Gorstein F, Balis ME. Treatment of hypoplastic anemia in mice with placental transplants. Blood. 50(4): 663-70, Oct 1977

  • Weiss G, Shenker L, Gorstein F. Suppurating myoma with spontaneous drainage through abdominal wall. New York State Journal of Medicine. 76(4): 572-3, Apr 1976

  • Chalon J, Katz JS, Gorstein F, Turndorf H. Malignant disease and tracheobronchial epithelial multinucleation. Cancer. 37(4): 1874-81, Apr 1976

  • Freidman-Mor Z, Chalon J, Katz JS, Gorstein F, Turndorf H, Orkin LR. Tracheobronchial and pulmonary cytologic changes in shock. Journal of Trauma. 16(1): 58-62, Jan 1976

  • Weiss G, Weick RF, Knobil E, Wolman SR, Gorstein F. An X-O anomaly and ovarian dysgenesis in a rhesus monkey. Folia Primatologica. 19(1): 24-7, 1973

  • Gelfand ML, Kantor T, Gorstein F. Cogan's syndrome with cardiovascular involvement: aortic insufficiency. Bulletin of the New York Academy of Medicine. 48(4): 647-60, May 1972

  • Winkelman J, Gorstein F. Quantitative studies on the accumulation of tetracycline in tumors. Experientia. 27(3): 309-10, Mar 1971

  • Dumont AE, Pugkhem T, Grosfeld J, Gorstein F. Alterations in splenic hilar lymphatics in patients with congestion of the spleen. Proceedings of the Society for Experimental Biology and Medicine. 135(3): 642-7, Dec 1970

  • Lehfeldt H, Tietze C, Gorstein F. Ovarian pregnancy and the intrauterine device. American Journal of Obstetrics and Gynecology. 108(7): 1005-9, Dec 1970

  • Katz J, Levitz M, Gorstein F, Troll W. Influence of trypsin on in vitro RNA synthesis by disrupted nuclei of rat and human uteri in different hormonal states. Endocrinology. 87(2): 294-301, Aug 1970

  • Beller FK, Graeff H, Gorstein F. Disseminated intravascular coagulation during the continuous infusion of endotoxin in rabbits. Morphologic and physiologic studies. American Journal of Obstetrics and Gynecology. 103(4): 544-54, Feb 1969

  • Mufson MA, Kawana R, Bloom HH, Gorstein F, Chanock RM. Pathogenicity of Coxsackie A-21 virus for suckling mice. Proceedings of the Society for Experimental Biology and Medicine. 128(1): 237-46, May 1968

  • Dancis J, Jansen V, Gorstein F, Douglas GW. Hematopoietic cells in mouse placenta. American Journal of Obstetrics and Gynecology. 100(8): 1110-21, Apr 1968

  • Young BK, Gorstein F. Maternal osteogenesis imperfecta. Obstetrics and Gynecology. 31(4): 461-70, Apr 1968

  • Gorstein F, Carroll HJ, Puszkin E. Electrolyte concentrations, potassium flux kinetics, and the metabolic dependence of potassium transport in human platelets. Journal of Laboratory and Clinical Medicine. 70(6): 938-50, Dec 1967

  • Beller FK, Mitchell PS, Gorstein F. Fibrin deposition in the ribbit kidney produced by protease inhibitors. Thrombosis Et Diathesis Haemorrhagica. 17(3-4): 427-39, May 1967

  • Phillips BP, Gorstein F. Effects of different species of bacteria on the pathology of enteric amebiasis in monocontaminated guinea pigs. American Journal of Tropical Medicine and Hygiene. 15(6): 863-8, Nov 1966

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