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Drug Discovery

Case Number Title Non-Confidential Summary Issued Patent Lead Inventor's Website
BAS_REN.005 Cell Lines which Constitutively Express IGF-1 and IGF-1 R   [US Patent No. 5,262,308]
     
Link
BEN_JEF.003 Compositions And Methods For Modulating The Activity Of G Protein-Kinases   [US Patent No. 6,255,069]
     
Link
BER_WOL.001 CalDAG-GEFI Inhibitors as Anti-Platelet Drugs NCS for BER_WOL.001          
BLO_TIM.002 Glucosidase Inhibitors as a Treatment for Viruses that Bud from the Endoplasmic Reticulum            
CHU_MON.001 Fibulin-2 Null Mutant Mice           Link
CRO_CAR.002 Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene NCS for Croce tumor suppressor techs (CRO 2,4,5,16)          
CRO_CAR.004 The Human FHIT Gene NCS for Croce tumor suppressor techs (CRO 2,4,5,16) [United States Patent: 7220834]
[United States Patent: 6774217]
[United States Patent: 6242212]
[United States Patent: 5928884]
 
CRO_CAR.009 TCL-1 Gene And Protein And Related Methods And Compositions NCS for Croce TCL-1 techs (CRO 9,15)          
CRO_CAR.015 Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression NCS for Croce TCL-1 techs (CRO 9,15)          
CRO_CAR.016 Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same NCS for Croce tumor suppressor techs (CRO 2,4,5,16)          
CRO_CAR.017 Role of microRNA Genes In Human Cancer NCS for Croce miRNA techs (CRO 17, 25)          
CRO_CAR.019 Involvement Of The ALL-1 Gene In A Solid Tumor1   [US Patent No. 5,567,586]
     
 
CRO_CAR.025 microRNA genes in cancer diagnosis and treatment NCS for Croce miRNA techs (CRO 17, 25)          
DAN_REN.001 Inhibition of HIV-1 replication in human peripheral blood monocytes through a clinically used drug           Link
DAN_REN.005 Methods to Measure Frequency of Integration in the Vicinity of Active Genes           Link
HOU_YAM.005 Apoptosis of Cardiomyocytes           Link
HOU_YAM.006 Antibiotics Targeting a Growth-Dependent Bacterial Enzyme           Link
IAC_LOR.001 A Human Model System For In Vitro Development Of The Dopaminergic Phenotype NCS for IAC_LOR.001 [US Patent No. 7,195,910]
     
Link
IOZ_REN.001 A Role For Decorin In Tumor Suppression   [US Patent No. 6,524,573]
     
Link
KHI_JAS.001 Humanized Cartilage in Mouse   [US Patent No. 6,448,470]
     
 
KMI_ERI.005 Methods for Enhancing Gene Conversion or Genetic Repair by Chimeric Oligonucleotides            
KOC_WAL.005 Adrenal Beta-Arrestin 1 is a Critical Regulator of Post-Myocardial Infarction Aldosterone Levels During Progression to Heart Failure           Link
KOP_HIL.006 Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins   [US Patent No. 6,042,832]
[US Patent No. 6,448,070]
   
Link
LIS_MIC.008 Autophagy in the Tumor Stroma: Is Cancer Eating Us Alive?           Link
NEV_MAR.001 Establishment of a New Human Androgen-Dependent Prostate Cancer Cell Line that is Tumorigenic in Nude Mice NCS for NEV_MAR.001         Link
NEV_MAR.005 A Pharmacological Inhibitor of Stat5a/b: IST5           Link
OSH_MIC.001 Chronic Recurring Migraine Headache Model in Rodents           Link
OSH_MIC.002 Inherited Rat Headache Model           Link
PASC_JOH.001 Crystal Structure of the Active Conformation of PARP-1 and Novel Binding Pockets for Inhibitor Design            
PIT_GIO.001 Three Novel Molecular Biomarkers for Colorectal Cancer Diagnosis and Treatment NCS for PIT_GIO.001          
RAB_JOS.001 Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression NCS for RAB_JOS.001         Link
SCH_JAY.008 Treatment of Parkinson's Disease and Parkinson's Disease Treatment-related Complications with RNA Inhibition Therapies NCS for SCH_JAY.001, 002, 004, 008         Link
SHI_YI.008 Prevention and Treatment of Metabolic Disorder-Associated Osteopenia/Osteoporosis and Bone Marrow Abnormalities            
SHI_YI.010 Prevention and Treatment of Vascular Dementia and Alzheimer's Disease            
SYK_YUR.004 Invention of a Novel Serum Free Media for Cultivation of Hybridoma Cells to Achieve Production of Highly Homogenous Monoclonal Antibodies (MAb) in Preparative Scale NCS for SYK_YUR.004         Link
TAR_THE.005 Malaria Drug Resistance is Associated with DNA Mismatch Repair Deficiency NCS for TAR_THE.005          
THO_JEF.001 Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal   [US Patent No. 6,358,536]
     
 
WIC_ERI.002 Peptide Nucleic Acid Conjugates   [US Patent No. 6,180,767]
     
Link
WIL_KEV.001 Human Genomic Clone Encoding Human Chondroitin 6-Sulfotransferase   [US Patent No. 6,399,358]
     
 
ZIT_NIC.001 Long Chain N-Alkyl Compounds and Oxa-Derivatives Thereof            

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