Philadelphia University + Thomas Jefferson University

Tomlinson, Ryan

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Ryan Tomlinson, PhD

Ryan Tomlinson, PhD

Contact Dr. Tomlinson

1015 Walnut Street
501 Curtis
Philadelphia, PA 19107

(215) 955-5504

Research and Clinical Interests

Sensory Nerves in Bone, Fracture Repair, Skeletal Mechanobiology

Publications

Most Recent Peer-Reviewed Publications

  1. Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function
  2. Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase
  3. NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice
  4. Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation
  5. Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
  6. NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone
  7. The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia
  8. Dysregulated TGF-β signaling alters bone microstructure in a mouse model of Loeys-Dietz syndrome
  9. HIF-1α regulates bone formation after osteogenic mechanical loading
  10. Nitric oxide-mediated vasodilation increases blood flow during the early stages of stress fracture healing
  11. Antagonizing the αvβ3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading
  12. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis
  13. Skeletal Blood Flow in Bone Repair and Maintenance
  14. Reduction in resorption cavity size following anti-resorptive drug treatment
  15. Anti-resorptive agents reduce the size of resorption cavities: A three-dimensional dynamic bone histomorphometry study
  16. Angiogenesis is required for stress fracture healing in rats
  17. Quantification of skeletal blood flow and fluoride metabolism in rats using PET in a pre-clinical stress fracture model
  18. Sub-micron 3D fluorescent imaging and visualization of remodeling cavities in cancellous bone
  19. Three-dimensional surface texture visualization of bone tissue through epifluorescence-based serial block face imaging
  20. Voxel size and measures of individual resorption cavities in three-dimensional images of cancellous bone