0B68 Calabretta, Bruno - Thomas Jefferson University - Thomas Jefferson University
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Bruno Calabretta, MD, PhD

Contact Dr. Calabretta

233 South 10th Street
Philadelphia, PA 19107

(215) 503-4522

Most Recent Peer-reviewed Publications

  1. Leukemia stem cells: Old concepts and new perspectives
  2. Autophagy in Chronic Myeloid Leukaemia: Stem cell survival and implication in therapy
  3. Erratum: Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells (Journal of Clinical Investigation (2009) 119:5 (1109-1123) DOI: 10.1172/JCI35660)
  4. MiRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia
  5. Leukemia stem cells: Old concepts and new perspectives
  6. Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion
  7. Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
  8. The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: Correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform
  9. Expression of p89 c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
  10. Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells
  11. Guidelines for the use and interpretation of assays for monitoring autophagy
  12. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
  13. Suppression of autophagy by BCR/ABL
  14. TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER + breast cancer cells
  15. Regulation of microRNA-145 by growth arrest and differentiation
  16. Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
  17. Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells
  18. The biological effects of C/EBPα in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain
  19. Expression of slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin
  20. Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model
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