Phyllis Flomenberg, MD
Philadelphia, PA 19107
(215) 923-1956 fax
Most Recent Peer-reviewed Publications
- Investigation of a Clostridium difficile cluster by multilocus sequence typing in a bone marrow transplant unit
- Adenovirus infections
- Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation
- A2-step approach to myeloablative haploidentical stem cell transplantation: A phase 1/2 trial performed with optimized T-cell dosing
- Risk factors for surgical site infections following spinal fusion procedures: A case-control study
Research and Clinical Interests
My focus of my research lab is on the analysis of human cellular immune responses to both viral pathogens and tumors and potential immunotherapy applications.
I have had a longstanding interest in adenovirus infections in patients with hematologic malignancies who undergo stem cell transplant recipients. I have an RO1 grant to characterize human T cell responses to adenoviruses in stem cell transplant recipients who develop adenovirus infections in order to develop immunotherapy strategies to help control invasive infections post-transplant, in collaboration with the Bone Marrow Transplant Program. Additionally, in collaboration with the Dept. of Neurosurgery, I have identified tumor-specific T cell responses in newly diagnosed patients with glioblastoma multiforme, suggesting that glioblastomas are immunogenic and may be amenable to immunotherapy.