0B68 Knudsen, Karen - Thomas Jefferson University - Thomas Jefferson University

Karen E. Knudsen, PhD

Contact Dr. Knudsen

233 South 10th Street
Suite 1008
Philadelphia, PA 19107

(215) 503-8574

Most Recent Peer-reviewed Publications

  1. Genomic prostate cancer classifier predicts biochemical failure and metastases in patients after postoperative radiation therapy
  2. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
  3. AR function in promoting metastatic prostate cancer
  4. Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells
  5. Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer
  6. AMPed up to treat prostate cancer: Novel AMPK activators emerge for cancer therapy
  7. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  8. Targeting cell cycle and hormone receptor pathways in cancer
  9. A hormone-DNA repair circuit governs the response to genotoxic insult
  10. Targeted radiosensitization of ETS fusion-positive prostate cancer through PARP1 inhibition
  11. IGF2 revs the steroidogenesis engine
  12. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
  13. Ex vivo culture of human prostate tissue and drug development
  14. Molecular pathogenesis and progression of prostate cancer
  15. Aberrant BAF57 signaling facilitates prometastatic phenotypes
  16. The role of tumor suppressor dysregulation in prostate cancer progression
  17. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes
  18. Dual roles of PARP-1 promote cancer growth and progression
  19. Cyclin D1 goes metabolic: Dual functions of cyclin D1 in regulating lipogenesis
  20. Evidence for efficacy of new hsp90 inhibitors revealed by ex vivo culture of human prostate tumors