282D OLeary, Michael - Thomas Jefferson University - Thomas Jefferson University

Michael E. O'Leary, PhD

Contact Dr.  O'Leary

900 Walnut Street
Philadelphia, PA 19107

(215) 503-9983

Most Recent Peer-reviewed Publications

  1. Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate
  2. Regulation/modulation of sensory neuron sodium channels.
  3. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons
  4. Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons
  5. Regulatory role of voltage-gated Na+ channel β subunits in sensory neurons
  6. Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits
  7. Single-cell analysis of sodium channel expression in dorsal root ganglion neurons
  8. Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels
  9. Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias
  10. Lidocaine promotes the trafficking and functional expression of Na v1.8 sodium channels in mammalian cells
  11. Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben
  12. State-dependent trapping of flecainide in the cardiac sodium channel
  13. Closing and Inactivation Potentiate the Cocaethylene Inhibition of Cardiac Sodium Channels by Distinct Mechanisms
  14. Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain
  15. Cocaine binds to a common site on open and inactivated human heart (Nav 1.5) sodium channels
  16. Inhibition of HERG potassium channels by cocaethylene: A metabolite of cocaine and ethanol
  17. Gating properties of Nav1.7 and Nav1.8 peripheral nerve sodium channels
  18. Inhibition of human ether-a-go-go potassium channels by cocaine
  19. Characterization of the isoform-specific differences in the gating of neuronal and muscle sodium channels
  20. A molecular link between activation and inactivation of sodium channels