05B4 OLeary, Michael - Thomas Jefferson University - Thomas Jefferson University

Michael E. O'Leary, PhD

Contact Dr.  O'Leary

900 Walnut Street
Philadelphia, PA 19107

(215) 503-9983

Most Recent Peer-reviewed Publications

  1. Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate
  2. Regulation/modulation of sensory neuron sodium channels.
  3. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons
  4. Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons
  5. Regulatory role of voltage-gated Na+ channel β subunits in sensory neurons
  6. Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits
  7. Single-cell analysis of sodium channel expression in dorsal root ganglion neurons
  8. Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels
  9. Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias
  10. Lidocaine promotes the trafficking and functional expression of Na v1.8 sodium channels in mammalian cells
  11. Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben
  12. State-dependent trapping of flecainide in the cardiac sodium channel
  13. Closing and Inactivation Potentiate the Cocaethylene Inhibition of Cardiac S 05B4 odium Channels by Distinct Mechanisms
  14. Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain
  15. Cocaine binds to a common site on open and inactivated human heart (Nav 1.5) sodium channels
  16. Inhibition of HERG potassium channels by cocaethylene: A metabolite of cocaine and ethanol
  17. Gating properties of Nav1.7 and Nav1.8 peripheral nerve sodium channels
  18. Inhibition of human ether-a-go-go potassium channels by cocaine
  19. Characterization of the isoform-specific differences in the gating of neuronal and muscle sodium channels
  20. A molecular link between activation and inactivation of sodium channels