27EC Pestell, Richard G. - Thomas Jefferson University - Thomas Jefferson University
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Richard G. Pestell, MD, PhD

Contact Dr. Pestell

233 South 10th Street
Room 1050
Philadelphia, PA 19107

(215) 503-5692
(215) 503-9334 fax

Most Recent Peer-reviewed Publications

  1. Antibiotics for cancer therapy
  2. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion
  3. Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction
  4. Loss of sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays park2 translocation to mitochondria
  5. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration
  6. A community effort to assess and improve drug sensitivity prediction algorithms
  7. A community computational challenge to predict the activity of pairs of compounds
  8. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines
  9. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling
  10. CAPER, a novel regulator of human breast cancer progression
  11. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: Past and present
  12. Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo
  13. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation
  14. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint
  15. MicroRNA-mediated cancer metastasis regulation via heterotypic signals in the microenvironment
  16. Acetylation-defective mutants of PparĪ³ are associated with decreased lipid synthesis in breast cancer cells
  17. The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster
  18. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1
  19. Caveolin-1 regulates the anti-atherogenic properties of macrophages
  20. The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells
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