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Yuri K. Sykulev, MD, PhD

Contact Dr. Sykulev

233 South 10th Street
Bluemle Life Sciences Building 706
Philadelphia, PA 19107

(215) 503-4530
(215) 923-4153 fax

Research and Clinical Interests

The major goal of my research program is to understand molecular mechanisms  regulating various activities of cytotoxic lymphocytes. Understanding of these mechanisms, particularly those that lead to the lymphocyte activation and inactivation, is expected to facilitate the development of novel approaches to manipulate lymphocytes receptor-mediated signaling and their responsiveness and would lead to the development of novel immunotherapeutic interventions to treat viral infections, cancer and other diseases.