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Tissue Engineering & Regenerative Medicine

The Tissue Engineering and Regenerative Engineering (TERM) PhD program has merged with the Cell and Developmental Biology (CDB) PhD program, and now constitutes a defined curricular track. Students who graduate from the TERM track will receive a degree in Cell and Developmental Biology with an identified concentration in Tissue Engineering and Regenerative Medicine.”


The concept of Tissue Engineering and Regenerative Medicine (TERM)  is an emerging multidisciplinary field involving biology, medicine and engineering and is focused on restoring maintaining or enhancing tissue and organ function.  The program is directed toward providing the students with formal instruction in both the classroom and laboratory; experience sufficient background to pursue and develop a scholarly scientific research project.

Tissue Engineering and Regenerative Medicine offers a unique environment where instructors, staff and administration work as a team to make your educational and research experience memorable and productive.  The program is organized by internationally recognized scientists who are faculty in a number of basic science and clinical departments within Thomas Jefferson University.  The graduate program provides sufficient flexibility so that graduating students can pursue a career in education research in an academic setting or industry.

We invite you to review program information. This page will provide you with admissions, general requirement and other important information to guide you through the enrollment process of the Cell & Developmental Biology Graduate Program.

Research Interests of Program Faculty in Regenerative Medicine

Key Faculty

George Feldman, PhD, DMD
Mutational analysis of hip dysplasia

Andrzej Fertala, PhD
Use use of "smart collagen" for tissue engineering; skeletal regeneration

Theresa Freeman, Phd
Effects of plasma discharge on cell function and renewal

Noreen J. Hickok, PhD
Bone biomaterial interaction and implant design; tissue engineering of bone and cartilage

Sergio Jimenez, MD
Pathogenesis of osteoarthritis and scleroderma

Javad Parvizi, FRCS, MD
Periprosthetic joint infection; pathophysiology of arthritis;

Makarand V. Risbud, PhD
Tissue-enginering based strategies for intervertebral disc regeneration

Irving M. Shapiro, BDS, PhD
Bone and cartilage formation; mechanisms of biological mineralization; design of implant materials; origin and function of cells of the intervertebral disc

Additional Faculty who have research that involves Tissue Engineering

Sophie Astroff, PhD
Cellular and molecular mechanisms of cardiovascular development, function of tissue microenvironment during development of the vertebrate heart from cardiac progenitors

Paul DiMuzio, MD, FACS
Tissue engineering of vascular grafts

Gerald B. Grunwald, PhD 
Role of cadherin cell adhesion molecules in embryonic development

Jan B. Hoek, PhD
Early signaling responses during liver regeneration

Lorraine Iacovitti, PhD
Mechanisms of neuronal cell differentiation and development of neurotransmitter class; application of immortalized stem cells to treat neurodegenerative diseases such as Parkinson's and Alzheimer's

Renato Iozzo, MD
Biology of proteoglycans and their roles in cancer and angiogenesis.

Steven B. McMahon, PhD
The ubiquitin hydrolase USP22 and cancer stem cells

A. Sue Menko, PhD
Tissue development, wound healing and tissue regeneration

Jay S. Schneider, PhD
Compensatory mechanisms after injury and "neurorestoration" - approaches to get dysfunctional or injured neurons to function more normally

Jouni J. Uitto, MD, PhD
Molecular biology of the cutaneous basement membranes

Rajanikanth Vadigepalli, PhD
Regulatory network dynamics driving the cellular adaptive processes in mammalian pathophysiology

Scott A. Waldman, PhD 
Molecular mechanisms underlying tissue-specific transcriptional regulation