Thomas Jefferson UniversityJefferson Graduate School of Biomedical Sciences

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Recent Publications

Cdc42 is required in a genetically distinct subset of cardiac cells during Drosophila dorsal vessel closure

Endorepellin evokes autophagy in endothelial cells

Cardiac fibroblast GSK-3β regulates ventricular remodeling and dysfunction in ischemic heart

Sorafenib cardiotoxicity increases mortality after myocardial infarction

Modulation of a voltage-gated Na+ channel by sevoflurane involves multiple sites and distinct mechanisms

CAPER, a novel regulator of human breast cancer progression

CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration

Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells

Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

C-kit+ cells minimally contribute cardiomyocytes to the heart

USP22 regulates oncogenic signaling pathways to drive lethal cancer progression

Matrix Biology Highlights

MICU1 motifs define mitochondrial calcium uniporter binding and activity

Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart

Decorin has an appetite for endothelial cell autophagy

The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)

Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues

Decorin causes autophagy in endothelial cells via Peg3