jlb104

Jeffrey L. Benovic, PhD

Contact Dr. Benovic

233 South Tenth Street
BLSB, Room 350
Philadelphia, PA 19107

(215) 503-4607
(215) 503-5393 fax

Most Recent Peer-reviewed Publications

  1. G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans
  2. β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction
  3. The αarrestin ARRDC3 regulates the endosomal residence time and intracellular signaling of the β2-adrenergic receptor
  4. From biased signalling to polypharmacology: Unlocking unique intracellular signalling using pepducins
  5. Interdicting Gq activation in airway disease by receptor-dependent and receptor-independent mechanisms
  6. Atomic structure of GRK5 reveals distinct structural features novel for G protein-coupled receptor kinases
  7. Structural biology: Arresting developments in receptor signalling
  8. New frontiers in kinases
  9. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization
  10. Consequence of the tumor-associated conversion to cyclin D1b
  11. Development and characterization of pepducins as Gs-biased allosteric agonists
  12. Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking
  13. Call for papers! a special thematic compilation/special issue crossover with ACS chemical biology, ACS medicinal chemistry letters, and the journal of medicinal chemistry focused on new frontiers in kinases
  14. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors
  15. β-Arrestins and G protein-coupled receptor trafficking
  16. β-Arrestins and G protein-coupled receptor trafficking
  17. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death
  18. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein
  19. G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation
  20. β-Arrestins and G protein-coupled receptor trafficking