0B68 Alnemri, Emad - Thomas Jefferson University - Thomas Jefferson University
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Emad Alnemri, PhD

Contact Dr. Alnemri

233 S. 10th Street
904 BLSB
Philadelphia, PA 19107

(215) 503-4632
(215) 923-1098 fax

Most Recent Peer-reviewed Publications

  1. Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
  2. Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4
  3. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
  4. Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function
  5. IKK╬▒ negatively regulates ASC-dependent inflammasome activation
  6. Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome
  7. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
  8. Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death
  9. Ribotoxic stress through p38 mitogen-activated protein kinase activates in Vitro the human pyrin inflammasome
  10. A novel role for the mitochondrial HTRA2/OMI protease in aging
  11. Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
  12. Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis
  13. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
  14. Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
  15. Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
  16. Cutting edge: Mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence
  17. Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes
  18. Sensing cytoplasmic danger signals by the inflammasome
  19. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
  20. Functional consequences of a germline mutation in the leucine-rich repeat domain of NLRP3 Identified in an atypical autoinflammatory disorder
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